ko pathway ratio_in_study ratio_in_pop p_value ko04010 MAPK signaling pathway 2/2 321/7206 0.00197845769287 ko04341 Hedgehog signaling pathway - fly 1/2 38/7206 0.0105196860585 ko05020 Prion diseases 1/2 40/7206 0.0110718128909 ko04962 Vasopressin-regulated water reabsorption 1/2 58/7206 0.0160340205356 ko04340 Hedgehog signaling pathway 1/2 58/7206 0.0160340205356 ko04961 Endocrine and other factor-regulated calcium reabsorption 1/2 59/7206 0.0163093327851 ko04742 Taste transduction 1/2 61/7206 0.0168598417196 ko04913 Ovarian steroidogenesis 1/2 63/7206 0.017410196569 ko05110 Vibrio cholerae infection 1/2 63/7206 0.017410196569 ko04113 Meiosis - yeast 1/2 70/7206 0.019335225118 ko05030 Cocaine addiction 1/2 73/7206 0.0201596595329 ko04923 Regulation of lipolysis in adipocytes 1/2 77/7206 0.0212583661201 ko04976 Bile secretion 1/2 80/7206 0.0220819915861 ko04740 Olfactory transduction 1/2 80/7206 0.0220819915861 ko04138 Autophagy - yeast 1/2 81/7206 0.0223564563652 ko04213 Longevity regulating pathway - multiple species 1/2 86/7206 0.0237282024407 ko04924 Renin secretion 1/2 86/7206 0.0237282024407 ko04918 Thyroid hormone synthesis 1/2 86/7206 0.0237282024407 ko05031 Amphetamine addiction 1/2 91/7206 0.025098985482 ko04970 Salivary secretion 1/2 95/7206 0.0261949185302 ko04971 Gastric acid secretion 1/2 98/7206 0.0270164638421 ko04720 Long-term potentiation 1/2 99/7206 0.0272902352371 ko05146 Amoebiasis 1/2 99/7206 0.0272902352371 ko04914 Progesterone-mediated oocyte maturation 1/2 104/7206 0.0286585143891 ko04925 Aldosterone synthesis and secretion 1/2 105/7206 0.0289320546551 ko04727 GABAergic synapse 1/2 110/7206 0.030299178166 ko05032 Morphine addiction 1/2 110/7206 0.030299178166 ko05414 Dilated cardiomyopathy 1/2 112/7206 0.0308457579208 ko04911 Insulin secretion 1/2 117/7206 0.0322115331835 ko04912 GnRH signaling pathway 1/2 122/7206 0.0335763454117 ko04750 Inflammatory mediator regulation of TRP channels 1/2 122/7206 0.0335763454117 ko04211 Longevity regulating pathway 1/2 123/7206 0.0338491922942 ko01522 Endocrine resistance 1/2 124/7206 0.0341220006542 ko04922 Glucagon signaling pathway 1/2 128/7206 0.0352128488814 ko04540 Gap junction 1/2 128/7206 0.0352128488814 ko04915 Estrogen signaling pathway 1/2 131/7206 0.0360305805773 ko04713 Circadian entrainment 1/2 136/7206 0.0373926963096 ko04726 Serotonergic synapse 1/2 137/7206 0.0376650038921 ko04114 Oocyte meiosis 1/2 139/7206 0.0382095034926 ko04916 Melanogenesis 1/2 142/7206 0.0390259639833 ko04919 Thyroid hormone signaling pathway 1/2 143/7206 0.0392980404373 ko04724 Glutamatergic synapse 1/2 152/7206 0.0417449950631 ko04270 Vascular smooth muscle contraction 1/2 154/7206 0.0422883390224 ko05012 Parkinson's disease 1/2 155/7206 0.0425599532197 ko04725 Cholinergic synapse 1/2 160/7206 0.0439174463882 ko04611 Platelet activation 1/2 163/7206 0.0447314800321 ko04140 Autophagy - animal 1/2 164/7206 0.0450027475377 ko04910 Insulin signaling pathway 1/2 172/7206 0.0471715008106 ko04723 Retrograde endocannabinoid signaling 1/2 175/7206 0.0479841476847 ko04371 Apelin signaling pathway 1/2 177/7206 0.0485257196617 ko04310 Wnt signaling pathway 1/2 181/7206 0.0496084013579