ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 32/296 191/7206 5.7368135851e-12 ko05340 Primary immunodeficiency 11/296 30/7206 1.27011557158e-08 ko05150 Staphylococcus aureus infection 11/296 36/7206 1.11972310931e-07 ko04380 Osteoclast differentiation 20/296 134/7206 4.54725216839e-07 ko00120 Primary bile acid biosynthesis 8/296 20/7206 6.03866660213e-07 ko05140 Leishmaniasis 14/296 75/7206 1.67100550799e-06 ko04650 Natural killer cell mediated cytotoxicity 16/296 97/7206 1.70710973213e-06 ko05321 Inflammatory bowel disease (IBD) 12/296 56/7206 2.03418424293e-06 ko04064 NF-kappa B signaling pathway 15/296 96/7206 7.23519691445e-06 ko04672 Intestinal immune network for IgA production 9/296 37/7206 1.32815634468e-05 ko04610 Complement and coagulation cascades 13/296 79/7206 1.67178160088e-05 ko04659 Th17 cell differentiation 15/296 106/7206 2.47315902852e-05 ko04630 Jak-STAT signaling pathway 17/296 132/7206 2.53017039296e-05 ko04660 T cell receptor signaling pathway 16/296 124/7206 4.28170837926e-05 ko04640 Hematopoietic cell lineage 11/296 64/7206 4.95334035555e-05 ko04621 NOD-like receptor signaling pathway 18/296 157/7206 7.09498857489e-05 ko00592 alpha-Linolenic acid metabolism 6/296 19/7206 7.874909754e-05 ko05320 Autoimmune thyroid disease 7/296 29/7206 0.000131480278524 ko05145 Toxoplasmosis 15/296 126/7206 0.000186912424577 ko05152 Tuberculosis 19/296 187/7206 0.000227447637133 ko04662 B cell receptor signaling pathway 12/296 88/7206 0.000230344639151 ko04612 Antigen processing and presentation 11/296 77/7206 0.000276653387779 ko05330 Allograft rejection 6/296 24/7206 0.000328303894038 ko05144 Malaria 8/296 45/7206 0.000421369836645 ko05168 Herpes simplex infection 18/296 182/7206 0.000461521096498 ko05310 Asthma 5/296 17/7206 0.000465338366451 ko04658 Th1 and Th2 cell differentiation 12/296 96/7206 0.000522507313444 ko05034 Alcoholism 1/296 238/7206 0.000740322376296 ko04145 Phagosome 16/296 162/7206 0.000961847092253 ko04611 Platelet activation 16/296 163/7206 0.0010277659823 ko00590 Arachidonic acid metabolism 8/296 52/7206 0.00114641314719 ko05162 Measles 13/296 120/7206 0.00122498996054 ko03320 PPAR signaling pathway 9/296 69/7206 0.00190873324468 ko05133 Pertussis 10/296 87/7206 0.00284936516481 ko04666 Fc gamma R-mediated phagocytosis 12/296 122/7206 0.00420156864809 ko05332 Graft-versus-host disease 4/296 18/7206 0.00540642014277 ko05132 Salmonella infection 10/296 98/7206 0.00671623288162 ko04310 Wnt signaling pathway 1/296 181/7206 0.0071480958485 ko04620 Toll-like receptor signaling pathway 10/296 100/7206 0.00772640029514 ko05164 Influenza A 14/296 167/7206 0.00943783511963 ko04910 Insulin signaling pathway 1/296 172/7206 0.0103842681569 ko04146 Peroxisome 9/296 89/7206 0.0104911810812 ko05323 Rheumatoid arthritis 9/296 89/7206 0.0104911810812 ko04670 Leukocyte transendothelial migration 13/296 151/7206 0.0106753416957 ko04622 RIG-I-like receptor signaling pathway 7/296 62/7206 0.0130478494812 ko04664 Fc epsilon RI signaling pathway 8/296 77/7206 0.0132553936289 ko04152 AMPK signaling pathway 1/296 161/7206 0.0149886117826 ko04550 Signaling pathways regulating pluripotency of stem cells 1/296 165/7206 0.0152597527042 ko00220 Arginine biosynthesis 4/296 24/7206 0.0154742213326 ko01040 Biosynthesis of unsaturated fatty acids 4/296 25/7206 0.017840746879 ko05131 Shigellosis 8/296 82/7206 0.0188466106222 ko04514 Cell adhesion molecules (CAMs) 11/296 130/7206 0.0217167963775 ko05416 Viral myocarditis 6/296 55/7206 0.0244327453045 ko04390 Hippo signaling pathway 2/296 188/7206 0.0249275687225 ko04360 Axon guidance 3/296 233/7206 0.0269175623699 ko04062 Chemokine signaling pathway 15/296 201/7206 0.0275661416083 ko04110 Cell cycle 1/296 145/7206 0.031630413463 ko04940 Type I diabetes mellitus 4/296 32/7206 0.0405834698207 ko00561 Glycerolipid metabolism 6/296 63/7206 0.0437418592349 ko05224 Breast cancer 2/296 174/7206 0.0497917954937