ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	173/1112	423/7206	3.04098215146e-39
ko04724	Glutamatergic synapse	80/1112	152/7206	4.24836265909e-27
ko05033	Nicotine addiction	40/1112	56/7206	6.28508719635e-21
ko04713	Circadian entrainment	64/1112	136/7206	1.42426296987e-18
ko04728	Dopaminergic synapse	77/1112	185/7206	3.5125718521e-18
ko04721	Synaptic vesicle cycle	46/1112	80/7206	4.32362506808e-18
ko05032	Morphine addiction	55/1112	110/7206	1.26225365432e-17
ko04727	GABAergic synapse	54/1112	110/7206	7.13122394523e-17
ko04020	Calcium signaling pathway	94/1112	265/7206	2.300887927e-16
ko04725	Cholinergic synapse	67/1112	160/7206	4.01612796217e-16
ko04723	Retrograde endocannabinoid signaling	69/1112	175/7206	5.81973290067e-15
ko04024	cAMP signaling pathway	92/1112	279/7206	8.00797079446e-14
ko04921	Oxytocin signaling pathway	75/1112	209/7206	1.44889119081e-13
ko04726	Serotonergic synapse	55/1112	137/7206	1.50786337245e-12
ko04911	Insulin secretion	49/1112	117/7206	4.00209859403e-12
ko05031	Amphetamine addiction	39/1112	91/7206	2.81957346747e-10
ko05322	Systemic lupus erythematosus	2/1112	151/7206	7.55525013744e-09
ko04742	Taste transduction	28/1112	61/7206	1.50378324318e-08
ko03010	Ribosome	1/1112	129/7206	1.80831689385e-08
ko04720	Long-term potentiation	38/1112	99/7206	1.94795861617e-08
ko04744	Phototransduction	20/1112	36/7206	3.05478963916e-08
ko04971	Gastric acid secretion	37/1112	98/7206	4.99379741147e-08
ko04925	Aldosterone synthesis and secretion	39/1112	105/7206	5.64959555808e-08
ko04261	Adrenergic signaling in cardiomyocytes	62/1112	205/7206	6.21263328588e-08
ko04970	Salivary secretion	36/1112	95/7206	6.7807811041e-08
ko03040	Spliceosome	3/1112	145/7206	1.47950486259e-07
ko04022	cGMP-PKG signaling pathway	60/1112	216/7206	2.16988947855e-06
ko04070	Phosphatidylinositol signaling system	37/1112	112/7206	3.77824397142e-06
ko04072	Phospholipase D signaling pathway	55/1112	197/7206	5.17169271977e-06
ko05203	Viral carcinogenesis	18/1112	277/7206	5.72267957809e-06
ko04966	Collecting duct acid secretion	14/1112	26/7206	6.22923184428e-06
ko04730	Long-term depression	28/1112	78/7206	8.61794649605e-06
ko04745	Phototransduction - fly	17/1112	38/7206	1.61174256694e-05
ko05030	Cocaine addiction	26/1112	73/7206	2.11889396308e-05
ko04110	Cell cycle	6/1112	145/7206	2.22496472542e-05
ko03013	RNA transport	8/1112	166/7206	2.76354983389e-05
ko04120	Ubiquitin mediated proteolysis	6/1112	138/7206	6.56848455056e-05
ko04750	Inflammatory mediator regulation of TRP channels	36/1112	122/7206	6.69450872492e-05
ko04710	Circadian rhythm	17/1112	43/7206	0.000109540771577
ko05168	Herpes simplex infection	11/1112	182/7206	0.000153796507107
ko04972	Pancreatic secretion	33/1112	111/7206	0.000153926656745
ko04010	MAPK signaling pathway	74/1112	321/7206	0.000254647157909
ko04141	Protein processing in endoplasmic reticulum	12/1112	184/7206	0.000271430805988
ko04270	Vascular smooth muscle contraction	41/1112	154/7206	0.000273127145998
ko05110	Vibrio cholerae infection	21/1112	63/7206	0.00033423735975
ko03008	Ribosome biogenesis in eukaryotes	2/1112	79/7206	0.000416461223963
ko04014	Ras signaling pathway	65/1112	279/7206	0.000486231263901
ko05014	Amyotrophic lateral sclerosis (ALS)	22/1112	74/7206	0.00171710595434
ko04915	Estrogen signaling pathway	34/1112	131/7206	0.00202007334382
ko04371	Apelin signaling pathway	43/1112	177/7206	0.0020628735589
ko00520	Amino sugar and nucleotide sugar metabolism	1/1112	55/7206	0.00210635029825
ko05166	HTLV-I infection	27/1112	292/7206	0.00212455571026
ko04924	Renin secretion	24/1112	86/7206	0.00250485180944
ko04740	Olfactory transduction	23/1112	80/7206	0.00257659238857
ko05161	Hepatitis B	13/1112	173/7206	0.00264359143255
ko04964	Proximal tubule bicarbonate reclamation	11/1112	29/7206	0.00265697289858
ko04922	Glucagon signaling pathway	33/1112	128/7206	0.00273248823348
ko04360	Axon guidance	53/1112	233/7206	0.00300655320437
ko05169	Epstein-Barr virus infection	17/1112	206/7206	0.00312793009854
ko04626	Plant-pathogen interaction	8/1112	18/7206	0.00322595841546
ko04540	Gap junction	32/1112	128/7206	0.00425046428174
ko05164	Influenza A	13/1112	167/7206	0.00454125136559
ko05219	Bladder cancer	1/1112	48/7206	0.00463248439305
ko04621	NOD-like receptor signaling pathway	12/1112	157/7206	0.00492899457363
ko04514	Cell adhesion molecules (CAMs)	32/1112	130/7206	0.00651430663839
ko03420	Nucleotide excision repair	1/1112	46/7206	0.00691299920212
ko04960	Aldosterone-regulated sodium reabsorption	13/1112	41/7206	0.00782207829264
ko05205	Proteoglycans in cancer	27/1112	271/7206	0.00993032032499
ko04612	Antigen processing and presentation	4/1112	77/7206	0.0101647190432
ko05133	Pertussis	5/1112	87/7206	0.0102116618438
ko03022	Basal transcription factors	1/1112	44/7206	0.0104491428988
ko05144	Malaria	1/1112	45/7206	0.0109045171386
ko00562	Inositol phosphate metabolism	23/1112	89/7206	0.0110868893558
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1112	14/7206	0.0131364933311
ko05200	Pathways in cancer	57/1112	492/7206	0.0139008707836
ko05140	Leishmaniasis	4/1112	75/7206	0.0145433373759
ko05162	Measles	9/1112	120/7206	0.0146861620503
ko04260	Cardiac muscle contraction	24/1112	98/7206	0.0164310987363
ko04330	Notch signaling pathway	3/1112	62/7206	0.0198774908245
ko04622	RIG-I-like receptor signaling pathway	3/1112	62/7206	0.0198774908245
ko04214	Apoptosis - fly	4/1112	72/7206	0.0200667454384
ko05016	Huntington's disease	21/1112	215/7206	0.0209056224839
ko04210	Apoptosis	17/1112	180/7206	0.0215047645779
ko04550	Signaling pathways regulating pluripotency of stem cells	15/1112	165/7206	0.0215947111558
ko04064	NF-kappa B signaling pathway	7/1112	96/7206	0.022623190664
ko03410	Base excision repair	1/1112	38/7206	0.0229227224127
ko05130	Pathogenic Escherichia coli infection	5/1112	77/7206	0.0258307644216
ko05206	MicroRNAs in cancer	17/1112	177/7206	0.0269944318502
ko05231	Choline metabolism in cancer	30/1112	134/7206	0.0294505675225
ko04060	Cytokine-cytokine receptor interaction	19/1112	191/7206	0.0327543435008
ko05145	Toxoplasmosis	11/1112	126/7206	0.0341358769882
ko04923	Regulation of lipolysis in adipocytes	19/1112	77/7206	0.0371851887083
ko04930	Type II diabetes mellitus	14/1112	54/7206	0.0379880949086
ko04711	Circadian rhythm - fly	5/1112	13/7206	0.0379972995999
ko05416	Viral myocarditis	3/1112	55/7206	0.0382685651815
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/1112	79/7206	0.0408214052505
ko04962	Vasopressin-regulated water reabsorption	15/1112	58/7206	0.041877908064
ko04912	GnRH signaling pathway	27/1112	122/7206	0.0432176043766
ko05131	Shigellosis	6/1112	82/7206	0.0441838360854
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/1112	59/7206	0.0443709997782