ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 41/390 191/7206 9.07372035417e-15 ko04380 Osteoclast differentiation 29/390 134/7206 7.34798988991e-11 ko04650 Natural killer cell mediated cytotoxicity 24/390 97/7206 1.78328792358e-10 ko05340 Primary immunodeficiency 13/390 30/7206 1.44910265436e-09 ko05321 Inflammatory bowel disease (IBD) 15/390 56/7206 1.61624717698e-07 ko04630 Jak-STAT signaling pathway 23/390 132/7206 4.91788565309e-07 ko05152 Tuberculosis 28/390 187/7206 7.33425888136e-07 ko04610 Complement and coagulation cascades 17/390 79/7206 7.47604416204e-07 ko05162 Measles 21/390 120/7206 1.44695584631e-06 ko05140 Leishmaniasis 16/390 75/7206 1.79536054045e-06 ko05145 Toxoplasmosis 21/390 126/7206 3.27574381913e-06 ko05168 Herpes simplex infection 26/390 182/7206 4.52309308429e-06 ko05164 Influenza A 24/390 167/7206 9.55044416069e-06 ko04621 NOD-like receptor signaling pathway 23/390 157/7206 1.06293144314e-05 ko04659 Th17 cell differentiation 18/390 106/7206 1.26874700788e-05 ko05150 Staphylococcus aureus infection 10/390 36/7206 1.37344315094e-05 ko05330 Allograft rejection 8/390 24/7206 2.34097088521e-05 ko04658 Th1 and Th2 cell differentiation 16/390 96/7206 4.87857689575e-05 ko04064 NF-kappa B signaling pathway 16/390 96/7206 4.87857689575e-05 ko04660 T cell receptor signaling pathway 18/390 124/7206 0.000109688345768 ko05144 Malaria 10/390 45/7206 0.000111228132802 ko04640 Hematopoietic cell lineage 12/390 64/7206 0.000134926385608 ko04612 Antigen processing and presentation 13/390 77/7206 0.000216737595986 ko05332 Graft-versus-host disease 6/390 18/7206 0.000257279227193 ko04217 Necroptosis 22/390 178/7206 0.000268433612488 ko04620 Toll-like receptor signaling pathway 15/390 100/7206 0.000282222567604 ko04145 Phagosome 20/390 162/7206 0.000546059765323 ko04672 Intestinal immune network for IgA production 8/390 37/7206 0.000660845254156 ko05320 Autoimmune thyroid disease 7/390 29/7206 0.000712284025297 ko04310 Wnt signaling pathway 1/390 181/7206 0.00071691775889 ko04662 B cell receptor signaling pathway 13/390 88/7206 0.000824530352251 ko04611 Platelet activation 19/390 163/7206 0.00132578510552 ko05167 Kaposi's sarcoma-associated herpesvirus infection 21/390 191/7206 0.00172015660664 ko05132 Salmonella infection 13/390 98/7206 0.00226061464829 ko04666 Fc gamma R-mediated phagocytosis 15/390 122/7206 0.00337467150999 ko04137 Mitophagy - animal 11/390 82/7206 0.00441498274813 ko03040 Spliceosome 1/390 145/7206 0.00477588397664 ko05034 Alcoholism 4/390 238/7206 0.00531628973234 ko04723 Retrograde endocannabinoid signaling 2/390 175/7206 0.00612535436275 ko04940 Type I diabetes mellitus 6/390 32/7206 0.00660187744693 ko00051 Fructose and mannose metabolism 7/390 42/7206 0.00671460731347 ko04916 Melanogenesis 1/390 142/7206 0.00726532051605 ko05418 Fluid shear stress and atherosclerosis 18/390 173/7206 0.00927011613614 ko03010 Ribosome 1/390 129/7206 0.0100682973325 ko04062 Chemokine signaling pathway 20/390 201/7206 0.0101412111415 ko05310 Asthma 4/390 17/7206 0.0114567916761 ko04390 Hippo signaling pathway 3/390 188/7206 0.0134443190153 ko05161 Hepatitis B 17/390 173/7206 0.0157943930571 ko05142 Chagas disease (American trypanosomiasis) 14/390 130/7206 0.0161328731713 ko00592 alpha-Linolenic acid metabolism 4/390 19/7206 0.0171312109326 ko04728 Dopaminergic synapse 3/390 185/7206 0.0193102880462 ko05202 Transcriptional misregulation in cancer 18/390 188/7206 0.0201891500867 ko00120 Primary bile acid biosynthesis 4/390 20/7206 0.0205218248927 ko04110 Cell cycle 2/390 145/7206 0.024533966743 ko04072 Phospholipase D signaling pathway 18/390 197/7206 0.0249647542561 ko03050 Proteasome 7/390 54/7206 0.0253575358728 ko05224 Breast cancer 3/390 174/7206 0.025872450763 ko05133 Pertussis 10/390 87/7206 0.0261901722176 ko04670 Leukocyte transendothelial migration 15/390 151/7206 0.0262604121673 ko05323 Rheumatoid arthritis 10/390 89/7206 0.0282613985219 ko04012 ErbB signaling pathway 1/390 109/7206 0.0306511293736 ko04972 Pancreatic secretion 1/390 111/7206 0.0312034899443 ko04664 Fc epsilon RI signaling pathway 9/390 77/7206 0.0359564950094 ko05012 Parkinson's disease 3/390 155/7206 0.0483321901211 ko04622 RIG-I-like receptor signaling pathway 7/390 62/7206 0.048902872621