ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 5/20 120/7206 1.49526643049e-05 ko05212 Pancreatic cancer 3/20 83/7206 0.00145830725498 ko04060 Cytokine-cytokine receptor interaction 4/20 191/7206 0.00166073119633 ko05200 Pathways in cancer 6/20 492/7206 0.0016680972608 ko04672 Intestinal immune network for IgA production 2/20 37/7206 0.00459869363023 ko05142 Chagas disease (American trypanosomiasis) 3/20 130/7206 0.00522511985387 ko04380 Osteoclast differentiation 3/20 134/7206 0.00568605440606 ko04933 AGE-RAGE signaling pathway in diabetic complications 3/20 135/7206 0.00580500687732 ko05166 HTLV-I infection 4/20 292/7206 0.00765205706082 ko05160 Hepatitis C 3/20 153/7206 0.00820731532833 ko04725 Cholinergic synapse 3/20 160/7206 0.00927873931685 ko04071 Sphingolipid signaling pathway 3/20 162/7206 0.0095993155007 ko05321 Inflammatory bowel disease (IBD) 2/20 56/7206 0.0103036194612 ko04068 FoxO signaling pathway 3/20 167/7206 0.0104291694394 ko04010 MAPK signaling pathway 4/20 321/7206 0.0106278601635 ko05213 Endometrial cancer 2/20 62/7206 0.0125268875025 ko05221 Acute myeloid leukemia 2/20 63/7206 0.0129161953644 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/20 182/7206 0.0131659372089 ko05168 Herpes simplex infection 3/20 182/7206 0.0131659372089 ko05223 Non-small cell lung cancer 2/20 66/7206 0.0141156959123 ko05152 Tuberculosis 3/20 187/7206 0.0141618238936 ko04072 Phospholipase D signaling pathway 3/20 197/7206 0.0162809006662 ko05214 Glioma 2/20 79/7206 0.0198438873908 ko05230 Central carbon metabolism in cancer 2/20 81/7206 0.0207990935108 ko05131 Shigellosis 2/20 82/7206 0.0212838686561 ko05220 Chronic myeloid leukemia 2/20 85/7206 0.0227665545374 ko05218 Melanoma 2/20 85/7206 0.0227665545374 ko05210 Colorectal cancer 2/20 86/7206 0.0232701461567 ko04924 Renin secretion 2/20 86/7206 0.0232701461567 ko05323 Rheumatoid arthritis 2/20 89/7206 0.0248086327667 ko05211 Renal cell carcinoma 2/20 96/7206 0.0285566737488 ko05100 Bacterial invasion of epithelial cells 2/20 99/7206 0.0302290875644 ko05146 Amoebiasis 2/20 99/7206 0.0302290875644 ko01521 EGFR tyrosine kinase inhibitor resistance 2/20 106/7206 0.0342805354253 ko04810 Regulation of actin cytoskeleton 3/20 264/7206 0.0349492718781 ko04012 ErbB signaling pathway 2/20 109/7206 0.0360791481599 ko05215 Prostate cancer 2/20 111/7206 0.0372984842055 ko05205 Proteoglycans in cancer 3/20 271/7206 0.0373511655587 ko04912 GnRH signaling pathway 2/20 122/7206 0.0442852650598 ko04750 Inflammatory mediator regulation of TRP channels 2/20 122/7206 0.0442852650598 ko04066 HIF-1 signaling pathway 2/20 123/7206 0.0449432880023 ko01522 Endocrine resistance 2/20 124/7206 0.0456050186367 ko05145 Toxoplasmosis 2/20 126/7206 0.0469395097387