ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	32/657	56/7206	1.35231199123e-19
ko04724	Glutamatergic synapse	48/657	152/7206	2.74392146198e-15
ko04080	Neuroactive ligand-receptor interaction	90/657	423/7206	3.82361892889e-15
ko04727	GABAergic synapse	39/657	110/7206	1.68548413769e-14
ko05032	Morphine addiction	38/657	110/7206	9.63508051379e-14
ko04360	Axon guidance	59/657	233/7206	1.13336280681e-13
ko04721	Synaptic vesicle cycle	30/657	80/7206	3.61928037796e-12
ko04728	Dopaminergic synapse	47/657	185/7206	3.59037456291e-11
ko04723	Retrograde endocannabinoid signaling	45/657	175/7206	6.15673728428e-11
ko04024	cAMP signaling pathway	58/657	279/7206	1.67819896822e-09
ko04725	Cholinergic synapse	39/657	160/7206	6.33767992292e-09
ko04744	Phototransduction	15/657	36/7206	1.92786467393e-07
ko04713	Circadian entrainment	32/657	136/7206	3.54764615997e-07
ko04010	MAPK signaling pathway	55/657	321/7206	3.55121353103e-06
ko04514	Cell adhesion molecules (CAMs)	29/657	130/7206	3.98568739408e-06
ko05030	Cocaine addiction	20/657	73/7206	4.91187203383e-06
ko04261	Adrenergic signaling in cardiomyocytes	39/657	205/7206	1.0266373857e-05
ko05203	Viral carcinogenesis	7/657	277/7206	1.53504477949e-05
ko03040	Spliceosome	1/657	145/7206	2.65980359073e-05
ko03013	RNA transport	2/657	166/7206	2.95060541739e-05
ko04020	Calcium signaling pathway	45/657	265/7206	4.39074407132e-05
ko04060	Cytokine-cytokine receptor interaction	4/657	191/7206	0.000110345522191
ko04726	Serotonergic synapse	27/657	137/7206	0.000115246305468
ko04911	Insulin secretion	24/657	117/7206	0.000124957779969
ko01200	Carbon metabolism	1/657	128/7206	0.0001309570117
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/657	79/7206	0.000202719122518
ko00515	Mannose type O-glycan biosynthesis	9/657	25/7206	0.00022077823679
ko04921	Oxytocin signaling pathway	35/657	209/7206	0.000345233486669
ko04621	NOD-like receptor signaling pathway	3/657	157/7206	0.00037484675365
ko05322	Systemic lupus erythematosus	3/657	151/7206	0.000807500292687
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/657	14/7206	0.000889604660706
ko04742	Taste transduction	14/657	61/7206	0.000937643264961
ko04120	Ubiquitin mediated proteolysis	3/657	138/7206	0.00154845824519
ko05014	Amyotrophic lateral sclerosis (ALS)	15/657	74/7206	0.00319662464271
ko04260	Cardiac muscle contraction	18/657	98/7206	0.00380465414949
ko00240	Pyrimidine metabolism	2/657	110/7206	0.00385230708076
ko04146	Peroxisome	1/657	89/7206	0.00438599437516
ko05031	Amphetamine addiction	17/657	91/7206	0.00476293936204
ko05205	Proteoglycans in cancer	12/657	271/7206	0.00484479302885
ko04217	Necroptosis	6/657	178/7206	0.00509029489502
ko03018	RNA degradation	1/657	84/7206	0.00631926042301
ko01230	Biosynthesis of amino acids	1/657	85/7206	0.00651584547053
ko05414	Dilated cardiomyopathy	19/657	112/7206	0.00724148342169
ko05146	Amoebiasis	2/657	99/7206	0.00772525909864
ko05016	Huntington's disease	9/657	215/7206	0.00781508631567
ko04930	Type II diabetes mellitus	11/657	54/7206	0.00840028877073
ko04391	Hippo signaling pathway - fly	16/657	90/7206	0.00853093215141
ko05168	Herpes simplex infection	7/657	182/7206	0.00873534804175
ko04141	Protein processing in endoplasmic reticulum	7/657	184/7206	0.00884290853419
ko04630	Jak-STAT signaling pathway	4/657	132/7206	0.00911983171815
ko05164	Influenza A	6/657	167/7206	0.00912747539259
ko04064	NF-kappa B signaling pathway	2/657	96/7206	0.0111768782639
ko04720	Long-term potentiation	17/657	99/7206	0.0120606587425
ko05169	Epstein-Barr virus infection	9/657	206/7206	0.0135229494054
ko05012	Parkinson's disease	6/657	155/7206	0.0163793631965
ko04066	HIF-1 signaling pathway	4/657	123/7206	0.0172588169067
ko04970	Salivary secretion	16/657	95/7206	0.0174376067478
ko05410	Hypertrophic cardiomyopathy (HCM)	16/657	100/7206	0.0222365051495
ko05162	Measles	4/657	120/7206	0.0238150596683
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/657	182/7206	0.0254438707359
ko04144	Endocytosis	43/657	342/7206	0.02670347086
ko04611	Platelet activation	7/657	163/7206	0.0271150825458
ko04140	Autophagy - animal	7/657	164/7206	0.0272121636327
ko04972	Pancreatic secretion	17/657	111/7206	0.0296285862191
ko04022	cGMP-PKG signaling pathway	29/657	216/7206	0.0304563369026
ko05210	Colorectal cancer	14/657	86/7206	0.0348264364188
ko04110	Cell cycle	6/657	145/7206	0.039478309315
ko05145	Toxoplasmosis	5/657	126/7206	0.0414182414879
ko02024	Quorum sensing	4/657	15/7206	0.0414437689936
ko04964	Proximal tubule bicarbonate reclamation	6/657	29/7206	0.0434600034685
ko01524	Platinum drug resistance	2/657	76/7206	0.0444179254043
ko04612	Antigen processing and presentation	2/657	77/7206	0.0446222247748