ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	148/757	423/7206	5.7188410808e-45
ko05033	Nicotine addiction	43/757	56/7206	1.39403554544e-31
ko04724	Glutamatergic synapse	66/757	152/7206	3.24454030212e-26
ko04727	GABAergic synapse	48/757	110/7206	1.93846080827e-19
ko05032	Morphine addiction	48/757	110/7206	1.93846080827e-19
ko04721	Synaptic vesicle cycle	37/757	80/7206	2.84753726265e-16
ko04723	Retrograde endocannabinoid signaling	57/757	175/7206	8.55780200346e-16
ko04728	Dopaminergic synapse	58/757	185/7206	3.31605033266e-15
ko04713	Circadian entrainment	46/757	136/7206	1.20364186888e-13
ko04024	cAMP signaling pathway	71/757	279/7206	3.76270070122e-13
ko04725	Cholinergic synapse	49/757	160/7206	1.35845726546e-12
ko04742	Taste transduction	26/757	61/7206	8.04466779344e-11
ko04911	Insulin secretion	37/757	117/7206	2.92819479522e-10
ko04726	Serotonergic synapse	39/757	137/7206	2.99569327898e-09
ko04020	Calcium signaling pathway	60/757	265/7206	4.55953903797e-09
ko05030	Cocaine addiction	25/757	73/7206	3.95489964634e-08
ko04261	Adrenergic signaling in cardiomyocytes	47/757	205/7206	1.6836514891e-07
ko04514	Cell adhesion molecules (CAMs)	34/757	130/7206	2.99726065008e-07
ko04010	MAPK signaling pathway	64/757	321/7206	3.13822023677e-07
ko05031	Amphetamine addiction	27/757	91/7206	3.31361238781e-07
ko04921	Oxytocin signaling pathway	47/757	209/7206	4.30910681853e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	23/757	74/7206	9.9954466226e-07
ko04970	Salivary secretion	26/757	95/7206	2.99065304922e-06
ko03040	Spliceosome	1/757	145/7206	3.1715177111e-06
ko05203	Viral carcinogenesis	9/757	277/7206	8.37246156871e-06
ko04972	Pancreatic secretion	28/757	111/7206	1.11593278414e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/757	79/7206	1.26795493654e-05
ko05164	Influenza A	3/757	167/7206	1.80195412506e-05
ko05168	Herpes simplex infection	4/757	182/7206	2.38208111875e-05
ko05205	Proteoglycans in cancer	10/757	271/7206	4.44217539409e-05
ko04120	Ubiquitin mediated proteolysis	2/757	138/7206	5.83741618957e-05
ko04720	Long-term potentiation	24/757	99/7206	7.94826619536e-05
ko05322	Systemic lupus erythematosus	3/757	151/7206	7.9950709647e-05
ko04730	Long-term depression	20/757	78/7206	0.000112258799005
ko04360	Axon guidance	44/757	233/7206	0.000115877803005
ko04260	Cardiac muscle contraction	23/757	98/7206	0.000170585739571
ko04744	Phototransduction	12/757	36/7206	0.000190625941783
ko04060	Cytokine-cytokine receptor interaction	6/757	191/7206	0.000270016800407
ko04621	NOD-like receptor signaling pathway	4/757	157/7206	0.000299573937956
ko03013	RNA transport	5/757	166/7206	0.000466394544561
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/757	182/7206	0.00135313068443
ko04141	Protein processing in endoplasmic reticulum	7/757	184/7206	0.00136831489277
ko05162	Measles	3/757	120/7206	0.00144644742887
ko05414	Dilated cardiomyopathy	23/757	112/7206	0.00153083792782
ko04217	Necroptosis	7/757	178/7206	0.00184597822574
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/757	14/7206	0.00188467327127
ko04540	Gap junction	25/757	128/7206	0.00195800940253
ko04964	Proximal tubule bicarbonate reclamation	9/757	29/7206	0.00213993387996
ko05169	Epstein-Barr virus infection	9/757	206/7206	0.00246167255238
ko03008	Ribosome biogenesis in eukaryotes	1/757	79/7206	0.00266355904043
ko04072	Phospholipase D signaling pathway	34/757	197/7206	0.0030704667873
ko04971	Gastric acid secretion	20/757	98/7206	0.00396356659039
ko00240	Pyrimidine metabolism	3/757	110/7206	0.00420287878366
ko04214	Apoptosis - fly	1/757	72/7206	0.00583608984011
ko04140	Autophagy - animal	7/757	164/7206	0.00630342932986
ko04146	Peroxisome	2/757	89/7206	0.00777194506521
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/757	59/7206	0.00853060723538
ko04110	Cell cycle	6/757	145/7206	0.00871379314705
ko04022	cGMP-PKG signaling pathway	35/757	216/7206	0.00906815297038
ko04925	Aldosterone synthesis and secretion	20/757	105/7206	0.00908833409247
ko04014	Ras signaling pathway	43/757	279/7206	0.00931104684973
ko04137	Mitophagy - animal	2/757	82/7206	0.0104997991539
ko03018	RNA degradation	2/757	84/7206	0.0107819278947
ko05166	HTLV-I infection	18/757	292/7206	0.0111254103061
ko04930	Type II diabetes mellitus	12/757	54/7206	0.0113582845299
ko04064	NF-kappa B signaling pathway	3/757	96/7206	0.0115846557389
ko05215	Prostate cancer	4/757	111/7206	0.01201454823
ko05410	Hypertrophic cardiomyopathy (HCM)	19/757	100/7206	0.0122812475239
ko04915	Estrogen signaling pathway	23/757	131/7206	0.0134472501581
ko04966	Collecting duct acid secretion	7/757	26/7206	0.0151554731
ko05161	Hepatitis B	9/757	173/7206	0.0169875925197
ko04218	Cellular senescence	9/757	177/7206	0.0174361895043
ko04150	mTOR signaling pathway	10/757	184/7206	0.0202238855064
ko05140	Leishmaniasis	2/757	75/7206	0.0215201536634
ko04612	Antigen processing and presentation	2/757	77/7206	0.0224310556172
ko04350	TGF-beta signaling pathway	4/757	103/7206	0.0227277576214
ko04976	Bile secretion	15/757	80/7206	0.0253714594242
ko00480	Glutathione metabolism	1/757	55/7206	0.026721110156
ko05321	Inflammatory bowel disease (IBD)	1/757	56/7206	0.0268243254404
ko01200	Carbon metabolism	6/757	128/7206	0.0281977997464
ko05016	Huntington's disease	13/757	215/7206	0.0311221272277
ko04510	Focal adhesion	15/757	240/7206	0.0313930983425
ko00310	Lysine degradation	2/757	73/7206	0.0317701380143
ko05110	Vibrio cholerae infection	12/757	63/7206	0.0365643470484
ko04973	Carbohydrate digestion and absorption	9/757	42/7206	0.0369942574496
ko04924	Renin secretion	15/757	86/7206	0.0487836187858
ko04962	Vasopressin-regulated water reabsorption	11/757	58/7206	0.0489991262965