ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	119/713	423/7206	2.7041179334e-28
ko04724	Glutamatergic synapse	63/713	152/7206	3.62026560494e-25
ko05033	Nicotine addiction	35/713	56/7206	5.69805206451e-22
ko04728	Dopaminergic synapse	64/713	185/7206	1.60078449699e-20
ko04721	Synaptic vesicle cycle	40/713	80/7206	5.47471713753e-20
ko04713	Circadian entrainment	48/713	136/7206	4.82850599066e-16
ko04727	GABAergic synapse	41/713	110/7206	8.12581734837e-15
ko05032	Morphine addiction	41/713	110/7206	8.12581734837e-15
ko04723	Retrograde endocannabinoid signaling	53/713	175/7206	2.20439896649e-14
ko04024	cAMP signaling pathway	69/713	279/7206	1.83849353523e-13
ko04911	Insulin secretion	39/713	117/7206	2.36871252614e-12
ko04725	Cholinergic synapse	46/713	160/7206	9.49476463521e-12
ko04020	Calcium signaling pathway	62/713	265/7206	6.18767572517e-11
ko04744	Phototransduction	19/713	36/7206	1.10290195576e-10
ko04726	Serotonergic synapse	40/713	137/7206	1.32614735555e-10
ko05031	Amphetamine addiction	30/713	91/7206	1.14874207664e-09
ko04921	Oxytocin signaling pathway	49/713	209/7206	5.0997899044e-09
ko04720	Long-term potentiation	30/713	99/7206	1.08559145652e-08
ko04261	Adrenergic signaling in cardiomyocytes	47/713	205/7206	3.07462962325e-08
ko05203	Viral carcinogenesis	5/713	277/7206	9.08232505292e-08
ko05030	Cocaine addiction	22/713	73/7206	1.11348708568e-06
ko04966	Collecting duct acid secretion	12/713	26/7206	2.09909501128e-06
ko04010	MAPK signaling pathway	58/713	321/7206	5.117741652e-06
ko04060	Cytokine-cytokine receptor interaction	3/713	191/7206	6.20795567382e-06
ko03040	Spliceosome	1/713	145/7206	7.37985229701e-06
ko05169	Epstein-Barr virus infection	4/713	206/7206	8.3638872828e-06
ko05164	Influenza A	2/713	167/7206	8.99011609543e-06
ko04970	Salivary secretion	24/713	95/7206	1.13696658848e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	20/713	74/7206	2.09932977455e-05
ko04730	Long-term depression	20/713	78/7206	4.81910689102e-05
ko04514	Cell adhesion molecules (CAMs)	28/713	130/7206	7.12987260562e-05
ko04070	Phosphatidylinositol signaling system	25/713	112/7206	7.97022422824e-05
ko04925	Aldosterone synthesis and secretion	23/713	105/7206	0.000203450749073
ko04971	Gastric acid secretion	22/713	98/7206	0.000210644566668
ko04072	Phospholipase D signaling pathway	36/713	197/7206	0.000238534000651
ko05322	Systemic lupus erythematosus	3/713	151/7206	0.000258605802655
ko05110	Vibrio cholerae infection	16/713	63/7206	0.000305036023021
ko03013	RNA transport	4/713	166/7206	0.000307015157514
ko05168	Herpes simplex infection	5/713	182/7206	0.000351063560135
ko04022	cGMP-PKG signaling pathway	38/713	216/7206	0.000434906703509
ko04260	Cardiac muscle contraction	21/713	98/7206	0.000516392973052
ko05162	Measles	2/713	120/7206	0.000575967945962
ko04621	NOD-like receptor signaling pathway	4/713	157/7206	0.000609926166321
ko04120	Ubiquitin mediated proteolysis	3/713	138/7206	0.000750157426097
ko04745	Phototransduction - fly	11/713	38/7206	0.000813545846834
ko05166	HTLV-I infection	13/713	292/7206	0.000866475791722
ko04972	Pancreatic secretion	22/713	111/7206	0.0012081250886
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/713	14/7206	0.00137493847578
ko04110	Cell cycle	4/713	145/7206	0.00171636002097
ko04742	Taste transduction	14/713	61/7206	0.00206861155724
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/713	92/7206	0.00213308203494
ko04014	Ras signaling pathway	43/713	279/7206	0.00287200659671
ko04141	Protein processing in endoplasmic reticulum	7/713	184/7206	0.00362098459648
ko04610	Complement and coagulation cascades	1/713	79/7206	0.00402734223528
ko04630	Jak-STAT signaling pathway	4/713	132/7206	0.00466068747276
ko04064	NF-kappa B signaling pathway	2/713	96/7206	0.00525192483753
ko04964	Proximal tubule bicarbonate reclamation	8/713	29/7206	0.00575541566596
ko05215	Prostate cancer	3/713	111/7206	0.00599781643291
ko04612	Antigen processing and presentation	1/713	77/7206	0.0060559828467
ko05161	Hepatitis B	7/713	173/7206	0.0063753602033
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/713	79/7206	0.00648835367077
ko04740	Olfactory transduction	16/713	80/7206	0.00682065171756
ko00310	Lysine degradation	1/713	73/7206	0.00890359324113
ko05222	Small cell lung cancer	2/713	89/7206	0.010982183839
ko05010	Alzheimer's disease	31/713	202/7206	0.0117993072435
ko05205	Proteoglycans in cancer	15/713	271/7206	0.0124386804036
ko04360	Axon guidance	35/713	233/7206	0.0134867273051
ko05034	Alcoholism	35/713	238/7206	0.0149265976918
ko05323	Rheumatoid arthritis	16/713	89/7206	0.0181738907266
ko04550	Signaling pathways regulating pluripotency of stem cells	8/713	165/7206	0.0245462620484
ko04626	Plant-pathogen interaction	5/713	18/7206	0.0268903189413
ko04924	Renin secretion	15/713	86/7206	0.0272447263238
ko00330	Arginine and proline metabolism	1/713	61/7206	0.0280342618771
ko05231	Choline metabolism in cancer	21/713	134/7206	0.0285343426825
ko04668	TNF signaling pathway	5/713	120/7206	0.0302960390683
ko05140	Leishmaniasis	2/713	75/7206	0.030962182708
ko04146	Peroxisome	3/713	89/7206	0.0319659256984
ko04611	Platelet activation	8/713	163/7206	0.0324915325968
ko04140	Autophagy - animal	8/713	164/7206	0.0328737315068
ko05200	Pathways in cancer	35/713	492/7206	0.0343022099162
ko04540	Gap junction	20/713	128/7206	0.0356297275946
ko04510	Focal adhesion	14/713	240/7206	0.0357395594125
ko00480	Glutathione metabolism	1/713	55/7206	0.039683834561
ko05321	Inflammatory bowel disease (IBD)	1/713	56/7206	0.040116471541
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/713	182/7206	0.0436713964384
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/713	59/7206	0.0437535507797
ko04071	Sphingolipid signaling pathway	24/713	162/7206	0.0444576514562
ko04657	IL-17 signaling pathway	3/713	87/7206	0.0446709094466
ko04750	Inflammatory mediator regulation of TRP channels	19/713	122/7206	0.0449854060346
ko00562	Inositol phosphate metabolism	15/713	89/7206	0.0462680269046