ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	147/797	423/7206	2.39666069177e-41
ko05033	Nicotine addiction	40/797	56/7206	1.69372162784e-26
ko04724	Glutamatergic synapse	67/797	152/7206	9.82692344105e-26
ko04728	Dopaminergic synapse	71/797	185/7206	7.42975421966e-23
ko04713	Circadian entrainment	56/797	136/7206	6.2383638965e-20
ko05032	Morphine addiction	48/797	110/7206	1.70147751177e-18
ko04727	GABAergic synapse	45/797	110/7206	4.1523325171e-16
ko04723	Retrograde endocannabinoid signaling	58/797	175/7206	2.07420668113e-15
ko04721	Synaptic vesicle cycle	35/797	80/7206	7.38583441791e-14
ko04725	Cholinergic synapse	51/797	160/7206	6.17382664732e-13
ko05031	Amphetamine addiction	36/797	91/7206	1.30377033467e-12
ko04020	Calcium signaling pathway	69/797	265/7206	3.54350134794e-12
ko04911	Insulin secretion	40/797	117/7206	1.75860478555e-11
ko04742	Taste transduction	27/797	61/7206	3.94844651774e-11
ko04921	Oxytocin signaling pathway	56/797	209/7206	1.26229403631e-10
ko04726	Serotonergic synapse	41/797	137/7206	1.05575010543e-09
ko04720	Long-term potentiation	33/797	99/7206	2.23907255942e-09
ko04024	cAMP signaling pathway	65/797	279/7206	2.3640597453e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	25/797	74/7206	1.49138210551e-07
ko04970	Salivary secretion	29/797	95/7206	1.87762275857e-07
ko04261	Adrenergic signaling in cardiomyocytes	48/797	205/7206	3.33129237356e-07
ko04730	Long-term depression	25/797	78/7206	4.70437532039e-07
ko05030	Cocaine addiction	23/797	73/7206	1.89155613398e-06
ko04514	Cell adhesion molecules (CAMs)	33/797	130/7206	3.19032288721e-06
ko04010	MAPK signaling pathway	61/797	321/7206	1.57871395472e-05
ko04745	Phototransduction - fly	14/797	38/7206	2.77106230107e-05
ko05322	Systemic lupus erythematosus	3/797	151/7206	3.64571534163e-05
ko05164	Influenza A	4/797	167/7206	4.75923182533e-05
ko04971	Gastric acid secretion	25/797	98/7206	5.22762176346e-05
ko04022	cGMP-PKG signaling pathway	44/797	216/7206	5.63547454202e-05
ko05168	Herpes simplex infection	5/797	182/7206	5.82607186385e-05
ko04070	Phosphatidylinositol signaling system	27/797	112/7206	8.9849797218e-05
ko04740	Olfactory transduction	21/797	80/7206	0.00011125405285
ko04360	Axon guidance	45/797	233/7206	0.000168801408217
ko04925	Aldosterone synthesis and secretion	25/797	105/7206	0.000202590415385
ko03013	RNA transport	5/797	166/7206	0.000229652222469
ko05203	Viral carcinogenesis	13/797	277/7206	0.000262416956842
ko04626	Plant-pathogen interaction	8/797	18/7206	0.000342817750621
ko04630	Jak-STAT signaling pathway	3/797	132/7206	0.000351185321803
ko04972	Pancreatic secretion	25/797	111/7206	0.000589226080889
ko04120	Ubiquitin mediated proteolysis	4/797	138/7206	0.000826620712534
ko04014	Ras signaling pathway	49/797	279/7206	0.000867732433287
ko04060	Cytokine-cytokine receptor interaction	8/797	191/7206	0.000965887150323
ko05162	Measles	3/797	120/7206	0.00100953624413
ko03008	Ribosome biogenesis in eukaryotes	1/797	79/7206	0.00175765313533
ko04141	Protein processing in endoplasmic reticulum	8/797	184/7206	0.00178742547088
ko04621	NOD-like receptor signaling pathway	6/797	157/7206	0.0017970019797
ko05169	Epstein-Barr virus infection	10/797	206/7206	0.00222150950063
ko04612	Antigen processing and presentation	1/797	77/7206	0.00271362723657
ko04924	Renin secretion	19/797	86/7206	0.00272372457565
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/797	79/7206	0.00301768026641
ko04146	Peroxisome	2/797	89/7206	0.0034541606449
ko00562	Inositol phosphate metabolism	19/797	89/7206	0.00545523380117
ko05166	HTLV-I infection	18/797	292/7206	0.00547797338728
ko04966	Collecting duct acid secretion	8/797	26/7206	0.00547810342414
ko04260	Cardiac muscle contraction	20/797	98/7206	0.00549408959149
ko04915	Estrogen signaling pathway	25/797	131/7206	0.00679817476072
ko04750	Inflammatory mediator regulation of TRP channels	23/797	122/7206	0.00860827452102
ko04540	Gap junction	24/797	128/7206	0.00959053232049
ko04964	Proximal tubule bicarbonate reclamation	8/797	29/7206	0.0111658090755
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/797	182/7206	0.011754251955
ko00330	Arginine and proline metabolism	1/797	61/7206	0.0123343766431
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/797	14/7206	0.0139402237799
ko04930	Type II diabetes mellitus	12/797	54/7206	0.0149421735012
ko04110	Cell cycle	7/797	145/7206	0.0150591774328
ko04214	Apoptosis - fly	2/797	72/7206	0.0214138967344
ko00310	Lysine degradation	2/797	73/7206	0.0219574552432
ko05110	Vibrio cholerae infection	13/797	63/7206	0.0239616651741
ko05205	Proteoglycans in cancer	19/797	271/7206	0.0294804493511
ko04071	Sphingolipid signaling pathway	27/797	162/7206	0.0300919543759
ko04064	NF-kappa B signaling pathway	4/797	96/7206	0.0312554848561
ko04015	Rap1 signaling pathway	42/797	278/7206	0.0318518658318
ko04922	Glucagon signaling pathway	22/797	128/7206	0.0322224205831
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/797	59/7206	0.0339430611633
ko04072	Phospholipase D signaling pathway	31/797	197/7206	0.0381112783581
ko04217	Necroptosis	11/797	178/7206	0.0385764645419
ko04960	Aldosterone-regulated sodium reabsorption	9/797	41/7206	0.0402130354237
ko00561	Glycerolipid metabolism	2/797	63/7206	0.0424198623745
ko04611	Platelet activation	10/797	163/7206	0.0426216675773
ko01524	Platinum drug resistance	3/797	76/7206	0.0429374414265
ko05130	Pathogenic Escherichia coli infection	3/797	77/7206	0.0430678014847
ko04610	Complement and coagulation cascades	3/797	79/7206	0.0443419443688
ko05034	Alcoholism	36/797	238/7206	0.0458459750793
ko00680	Methane metabolism	8/797	34/7206	0.047239467604
ko05161	Hepatitis B	11/797	173/7206	0.0486999547085