ko pathway ratio_in_study ratio_in_pop p_value ko04722 Neurotrophin signaling pathway 3/5 160/7206 0.000103983151076 ko04910 Insulin signaling pathway 3/5 172/7206 0.000129020722064 ko05219 Bladder cancer 2/5 48/7206 0.000428997909452 ko04024 cAMP signaling pathway 3/5 279/7206 0.000541905459895 ko05213 Endometrial cancer 2/5 62/7206 0.000716379624781 ko05221 Acute myeloid leukemia 2/5 63/7206 0.000739661220067 ko05223 Non-small cell lung cancer 2/5 66/7206 0.000811698198538 ko04370 VEGF signaling pathway 2/5 77/7206 0.00110384675404 ko04664 Fc epsilon RI signaling pathway 2/5 77/7206 0.00110384675404 ko05214 Glioma 2/5 79/7206 0.00116167253297 ko05230 Central carbon metabolism in cancer 2/5 81/7206 0.00122094066455 ko05220 Chronic myeloid leukemia 2/5 85/7206 0.00134379405434 ko05218 Melanoma 2/5 85/7206 0.00134379405434 ko04917 Prolactin signaling pathway 2/5 87/7206 0.00140737435216 ko04662 B cell receptor signaling pathway 2/5 88/7206 0.00143970181776 ko05211 Renal cell carcinoma 2/5 96/7206 0.00171117632411 ko04650 Natural killer cell mediated cytotoxicity 2/5 97/7206 0.00174671285251 ko04620 Toll-like receptor signaling pathway 2/5 100/7206 0.00185545132249 ko01521 EGFR tyrosine kinase inhibitor resistance 2/5 106/7206 0.00208248054027 ko04012 ErbB signaling pathway 2/5 109/7206 0.00220075468867 ko05215 Prostate cancer 2/5 111/7206 0.00228136128615 ko04668 TNF signaling pathway 2/5 120/7206 0.00266141615899 ko04066 HIF-1 signaling pathway 2/5 123/7206 0.00279437550263 ko04660 T cell receptor signaling pathway 2/5 124/7206 0.00283938979246 ko01522 Endocrine resistance 2/5 124/7206 0.00283938979246 ko04915 Estrogen signaling pathway 2/5 131/7206 0.00316418167125 ko05231 Choline metabolism in cancer 2/5 134/7206 0.00330855352632 ko04919 Thyroid hormone signaling pathway 2/5 143/7206 0.00376019651171 ko04071 Sphingolipid signaling pathway 2/5 162/7206 0.00480409898792 ko04140 Autophagy - animal 2/5 164/7206 0.00492105973716 ko04550 Signaling pathways regulating pluripotency of stem cells 2/5 165/7206 0.00498004225846 ko05164 Influenza A 2/5 167/7206 0.00509901009769 ko04068 FoxO signaling pathway 2/5 167/7206 0.00509901009769 ko05161 Hepatitis B 2/5 173/7206 0.00546391445768 ko05224 Breast cancer 2/5 174/7206 0.00552589550426 ko05206 MicroRNAs in cancer 2/5 177/7206 0.00571382751175 ko04218 Cellular senescence 2/5 177/7206 0.00571382751175 ko04210 Apoptosis 2/5 180/7206 0.00590473656517 ko04150 mTOR signaling pathway 2/5 184/7206 0.00616389904539 ko05167 Kaposi's sarcoma-associated herpesvirus infection 2/5 191/7206 0.00663007698521 ko04072 Phospholipase D signaling pathway 2/5 197/7206 0.00704240038732 ko04810 Regulation of actin cytoskeleton 2/5 264/7206 0.0124265374597 ko05205 Proteoglycans in cancer 2/5 271/7206 0.0130696443863 ko04015 Rap1 signaling pathway 2/5 278/7206 0.0137276160314 ko04014 Ras signaling pathway 2/5 279/7206 0.0138228197179 ko04010 MAPK signaling pathway 2/5 321/7206 0.0180897521671 ko05216 Thyroid cancer 1/5 34/7206 0.0233763045377 ko04151 PI3K-Akt signaling pathway 2/5 390/7206 0.0261978477966 ko05020 Prion diseases 1/5 40/7206 0.0274557630477 ko04960 Aldosterone-regulated sodium reabsorption 1/5 41/7206 0.0281343454065 ko04973 Carbohydrate digestion and absorption 1/5 42/7206 0.0288125489337 ko04930 Type II diabetes mellitus 1/5 54/7206 0.0369215000856 ko05200 Pathways in cancer 2/5 492/7206 0.0405153581773