ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	32/511	56/7206	5.80007712612e-23
ko04721	Synaptic vesicle cycle	37/511	80/7206	4.23580079483e-22
ko04080	Neuroactive ligand-receptor interaction	88/511	423/7206	1.7502319413e-21
ko04724	Glutamatergic synapse	48/511	152/7206	8.93089691302e-20
ko04723	Retrograde endocannabinoid signaling	45/511	175/7206	7.93479365123e-15
ko04728	Dopaminergic synapse	45/511	185/7206	7.17484657423e-14
ko04727	GABAergic synapse	33/511	110/7206	3.20290547778e-13
ko05032	Morphine addiction	33/511	110/7206	3.20290547778e-13
ko04713	Circadian entrainment	34/511	136/7206	4.09013006742e-11
ko05014	Amyotrophic lateral sclerosis (ALS)	21/511	74/7206	2.13340477494e-08
ko04725	Cholinergic synapse	31/511	160/7206	1.96002173328e-07
ko04911	Insulin secretion	25/511	117/7206	4.47204686523e-07
ko05030	Cocaine addiction	19/511	73/7206	4.51514231556e-07
ko04966	Collecting duct acid secretion	11/511	26/7206	5.95062216778e-07
ko04024	cAMP signaling pathway	42/511	279/7206	2.26674315441e-06
ko04726	Serotonergic synapse	26/511	137/7206	2.88665542991e-06
ko05031	Amphetamine addiction	20/511	91/7206	4.04344315593e-06
ko04010	MAPK signaling pathway	44/511	321/7206	1.7756283593e-05
ko04261	Adrenergic signaling in cardiomyocytes	32/511	205/7206	2.03675761084e-05
ko04060	Cytokine-cytokine receptor interaction	1/511	191/7206	2.04655284954e-05
ko05110	Vibrio cholerae infection	15/511	63/7206	2.37907026393e-05
ko04360	Axon guidance	34/511	233/7206	4.34523711915e-05
ko04742	Taste transduction	14/511	61/7206	6.85961931893e-05
ko04514	Cell adhesion molecules (CAMs)	22/511	130/7206	0.000168209377933
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/511	92/7206	0.000212770109143
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/511	14/7206	0.000226765297337
ko04145	Phagosome	25/511	162/7206	0.00024652225683
ko03040	Spliceosome	1/511	145/7206	0.000456625554772
ko04921	Oxytocin signaling pathway	29/511	209/7206	0.000490280273648
ko04120	Ubiquitin mediated proteolysis	1/511	138/7206	0.00066893954244
ko04964	Proximal tubule bicarbonate reclamation	8/511	29/7206	0.000685510122973
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/511	59/7206	0.000733677843918
ko04970	Salivary secretion	16/511	95/7206	0.000943246173949
ko04730	Long-term depression	14/511	78/7206	0.00102122177143
ko03013	RNA transport	2/511	166/7206	0.00102345563345
ko05203	Viral carcinogenesis	7/511	277/7206	0.00114072311442
ko05323	Rheumatoid arthritis	15/511	89/7206	0.00133888820972
ko05322	Systemic lupus erythematosus	2/511	151/7206	0.0019933079514
ko04720	Long-term potentiation	16/511	99/7206	0.00213795710952
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	13/511	79/7206	0.00341457385882
ko04260	Cardiac muscle contraction	15/511	98/7206	0.00425834331959
ko05168	Herpes simplex infection	4/511	182/7206	0.00510047744182
ko04141	Protein processing in endoplasmic reticulum	4/511	184/7206	0.00515197352213
ko04972	Pancreatic secretion	16/511	111/7206	0.00743458985969
ko01200	Carbon metabolism	2/511	128/7206	0.00830958604259
ko00564	Glycerophospholipid metabolism	1/511	99/7206	0.00958642681385
ko04540	Gap junction	17/511	128/7206	0.0131308843546
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/511	8/7206	0.0151661076025
ko05162	Measles	2/511	120/7206	0.0175478746213
ko04146	Peroxisome	1/511	89/7206	0.0203768744176
ko05205	Proteoglycans in cancer	10/511	271/7206	0.0217990095498
ko04015	Rap1 signaling pathway	30/511	278/7206	0.0225536609403
ko04014	Ras signaling pathway	30/511	279/7206	0.0228148991267
ko04630	Jak-STAT signaling pathway	3/511	132/7206	0.0248687710816
ko04621	NOD-like receptor signaling pathway	4/511	157/7206	0.0257967518522
ko04973	Carbohydrate digestion and absorption	7/511	42/7206	0.0266942300549
ko04071	Sphingolipid signaling pathway	19/511	162/7206	0.0286170958815
ko03018	RNA degradation	1/511	84/7206	0.0297321721041
ko04022	cGMP-PKG signaling pathway	24/511	216/7206	0.0297857418843
ko01230	Biosynthesis of amino acids	1/511	85/7206	0.0301652808184
ko05164	Influenza A	5/511	167/7206	0.0322913164006
ko04915	Estrogen signaling pathway	16/511	131/7206	0.0364039173082
ko04612	Antigen processing and presentation	1/511	77/7206	0.0424924053216
ko04140	Autophagy - animal	5/511	164/7206	0.0435996023522
ko05146	Amoebiasis	2/511	99/7206	0.0466573062112
ko04211	Longevity regulating pathway	3/511	123/7206	0.0482717065415