ko pathway ratio_in_study ratio_in_pop p_value ko04916 Melanogenesis 15/66 142/7206 1.41559178596e-12 ko04310 Wnt signaling pathway 13/66 181/7206 6.5876267318e-09 ko05217 Basal cell carcinoma 8/66 68/7206 1.53501264765e-07 ko04550 Signaling pathways regulating pluripotency of stem cells 11/66 165/7206 2.34991588475e-07 ko05200 Pathways in cancer 16/66 492/7206 6.14135493465e-06 ko04390 Hippo signaling pathway 10/66 188/7206 6.82184390273e-06 ko05224 Breast cancer 9/66 174/7206 2.57184153655e-05 ko05205 Proteoglycans in cancer 11/66 271/7206 2.96091588576e-05 ko04080 Neuroactive ligand-receptor interaction 13/66 423/7206 9.58798742169e-05 ko04360 Axon guidance 9/66 233/7206 0.000245525976323 ko04150 mTOR signaling pathway 8/66 184/7206 0.000251274148045 ko04745 Phototransduction - fly 4/66 38/7206 0.000374943285122 ko05166 HTLV-I infection 9/66 292/7206 0.00126208932164 ko04720 Long-term potentiation 5/66 99/7206 0.00203726223088 ko04020 Calcium signaling pathway 8/66 265/7206 0.0027190341101 ko04022 cGMP-PKG signaling pathway 7/66 216/7206 0.00342365569173 ko04015 Rap1 signaling pathway 8/66 278/7206 0.00364975670606 ko04922 Glucagon signaling pathway 5/66 128/7206 0.00615094877296 ko00830 Retinol metabolism 3/66 42/7206 0.00653022148216 ko04915 Estrogen signaling pathway 5/66 131/7206 0.00677548685544 ko04924 Renin secretion 4/66 86/7206 0.0077697974386 ko04114 Oocyte meiosis 5/66 139/7206 0.00865669096582 ko04151 PI3K-Akt signaling pathway 9/66 390/7206 0.00867168892058 ko05031 Amphetamine addiction 4/66 91/7206 0.00945225993163 ko04970 Salivary secretion 4/66 95/7206 0.0109574337736 ko04626 Plant-pathogen interaction 2/66 18/7206 0.0115012281325 ko04014 Ras signaling pathway 7/66 279/7206 0.0133719397951 ko04016 MAPK signaling pathway - plant 2/66 20/7206 0.0141156959123 ko04722 Neurotrophin signaling pathway 5/66 160/7206 0.0152588761086 ko04925 Aldosterone synthesis and secretion 4/66 105/7206 0.0153749591521 ko05215 Prostate cancer 4/66 111/7206 0.0184966934913 ko04013 MAPK signaling pathway - fly 4/66 115/7206 0.0207821851607 ko04371 Apelin signaling pathway 5/66 177/7206 0.0226025414644 ko04912 GnRH signaling pathway 4/66 122/7206 0.0251857758377 ko04750 Inflammatory mediator regulation of TRP channels 4/66 122/7206 0.0251857758377 ko04728 Dopaminergic synapse 5/66 185/7206 0.0267388783067 ko05014 Amyotrophic lateral sclerosis (ALS) 3/66 74/7206 0.0299933829018 ko04370 VEGF signaling pathway 3/66 77/7206 0.0332011036537 ko04730 Long-term depression 3/66 78/7206 0.0343087032928 ko05214 Glioma 3/66 79/7206 0.0354354032848 ko04713 Circadian entrainment 4/66 136/7206 0.0355795584457 ko04726 Serotonergic synapse 4/66 137/7206 0.0364043276497 ko05010 Alzheimer's disease 5/66 202/7206 0.037066057524 ko05216 Thyroid cancer 2/66 34/7206 0.0384039610667 ko04024 cAMP signaling pathway 6/66 279/7206 0.0416700000088 ko04921 Oxytocin signaling pathway 5/66 209/7206 0.0419466132041 ko05220 Chronic myeloid leukemia 3/66 85/7206 0.0425934335107 ko04744 Phototransduction 2/66 36/7206 0.0426289945628 ko05210 Colorectal cancer 3/66 86/7206 0.0438521191517 ko04662 B cell receptor signaling pathway 3/66 88/7206 0.0464251069239 ko04391 Hippo signaling pathway - fly 3/66 90/7206 0.0490716851739