ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	104/722	423/7206	2.48140164058e-19
ko04724	Glutamatergic synapse	49/722	152/7206	2.40378475643e-14
ko04713	Circadian entrainment	44/722	136/7206	4.59268970861e-13
ko05032	Morphine addiction	38/722	110/7206	1.911198189e-12
ko04727	GABAergic synapse	37/722	110/7206	9.40746386816e-12
ko05033	Nicotine addiction	25/722	56/7206	1.92503288031e-11
ko04721	Synaptic vesicle cycle	30/722	80/7206	4.03722509022e-11
ko04728	Dopaminergic synapse	47/722	185/7206	9.18602365922e-10
ko04020	Calcium signaling pathway	59/722	265/7206	1.92773605274e-09
ko04725	Cholinergic synapse	42/722	160/7206	2.55522979437e-09
ko04921	Oxytocin signaling pathway	50/722	209/7206	2.66271268325e-09
ko04970	Salivary secretion	29/722	95/7206	2.1106663175e-08
ko04726	Serotonergic synapse	36/722	137/7206	3.48699972382e-08
ko04723	Retrograde endocannabinoid signaling	42/722	175/7206	5.15576269396e-08
ko04911	Insulin secretion	32/722	117/7206	7.33518470124e-08
ko04024	cAMP signaling pathway	57/722	279/7206	1.146420397e-07
ko05168	Herpes simplex infection	2/722	182/7206	1.94246013936e-06
ko04261	Adrenergic signaling in cardiomyocytes	43/722	205/7206	2.36866576242e-06
ko04966	Collecting duct acid secretion	12/722	26/7206	2.40023601302e-06
ko05322	Systemic lupus erythematosus	1/722	151/7206	3.25467320395e-06
ko05031	Amphetamine addiction	24/722	91/7206	6.33706990334e-06
ko04742	Taste transduction	18/722	61/7206	1.73388044121e-05
ko05169	Epstein-Barr virus infection	5/722	206/7206	3.03205801063e-05
ko04972	Pancreatic secretion	26/722	111/7206	3.39481286465e-05
ko03010	Ribosome	1/722	129/7206	3.80631682149e-05
ko04022	cGMP-PKG signaling pathway	41/722	216/7206	4.51387168109e-05
ko03040	Spliceosome	2/722	145/7206	6.1189198526e-05
ko04922	Glucagon signaling pathway	28/722	128/7206	6.83286929365e-05
ko05162	Measles	1/722	120/7206	8.1266062373e-05
ko05166	HTLV-I infection	11/722	292/7206	8.73291124e-05
ko05203	Viral carcinogenesis	10/722	277/7206	8.73304144497e-05
ko04925	Aldosterone synthesis and secretion	24/722	105/7206	9.58249606968e-05
ko05110	Vibrio cholerae infection	17/722	63/7206	0.000103525157436
ko04971	Gastric acid secretion	23/722	98/7206	0.000104032047134
ko04720	Long-term potentiation	23/722	99/7206	0.000114529287524
ko04060	Cytokine-cytokine receptor interaction	5/722	191/7206	0.000122746681574
ko04730	Long-term depression	19/722	78/7206	0.000183721302081
ko03013	RNA transport	4/722	166/7206	0.000211141311078
ko05164	Influenza A	4/722	167/7206	0.000211659073078
ko05030	Cocaine addiction	18/722	73/7206	0.00022902962273
ko00010	Glycolysis / Gluconeogenesis	18/722	74/7206	0.000274949130126
ko04070	Phosphatidylinositol signaling system	24/722	112/7206	0.000327489632123
ko01230	Biosynthesis of amino acids	20/722	85/7206	0.000327787540008
ko04120	Ubiquitin mediated proteolysis	3/722	138/7206	0.000509325204259
ko04745	Phototransduction - fly	11/722	38/7206	0.000904216757946
ko04110	Cell cycle	4/722	145/7206	0.00119723274719
ko00680	Methane metabolism	10/722	34/7206	0.00134461767095
ko04514	Cell adhesion molecules (CAMs)	25/722	130/7206	0.00160370866156
ko05161	Hepatitis B	6/722	173/7206	0.00188201758601
ko04744	Phototransduction	10/722	36/7206	0.00216761165314
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/722	92/7206	0.00227848518951
ko05014	Amyotrophic lateral sclerosis (ALS)	16/722	74/7206	0.00265675281587
ko04710	Circadian rhythm	11/722	43/7206	0.00271676218609
ko04510	Focal adhesion	11/722	240/7206	0.00292870631924
ko04371	Apelin signaling pathway	30/722	177/7206	0.003392775254
ko00290	Valine, leucine and isoleucine biosynthesis	3/722	4/7206	0.00370824383795
ko03008	Ribosome biogenesis in eukaryotes	1/722	79/7206	0.00402260095096
ko05224	Breast cancer	7/722	174/7206	0.00469318917498
ko04658	Th1 and Th2 cell differentiation	2/722	96/7206	0.00531936694903
ko04924	Renin secretion	17/722	86/7206	0.00568409358875
ko05140	Leishmaniasis	1/722	75/7206	0.00591720707026
ko04964	Proximal tubule bicarbonate reclamation	8/722	29/7206	0.00620993027259
ko05200	Pathways in cancer	32/722	492/7206	0.00631323588866
ko04626	Plant-pathogen interaction	6/722	18/7206	0.00640413953324
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/722	59/7206	0.00671159747212
ko04659	Th17 cell differentiation	3/722	106/7206	0.00842066662325
ko04214	Apoptosis - fly	1/722	72/7206	0.00884178798126
ko04270	Vascular smooth muscle contraction	26/722	154/7206	0.00913221397607
ko04260	Cardiac muscle contraction	18/722	98/7206	0.0100464523794
ko05206	MicroRNAs in cancer	8/722	177/7206	0.0107408798857
ko01200	Carbon metabolism	22/722	128/7206	0.0107627330963
ko05133	Pertussis	2/722	87/7206	0.0107711196492
ko04217	Necroptosis	8/722	178/7206	0.0108253887686
ko00120	Primary bile acid biosynthesis	6/722	20/7206	0.0112418969786
ko04630	Jak-STAT signaling pathway	5/722	132/7206	0.0122170101773
ko05217	Basal cell carcinoma	1/722	68/7206	0.0129704800488
ko04740	Olfactory transduction	15/722	80/7206	0.0141507625374
ko04621	NOD-like receptor signaling pathway	7/722	157/7206	0.0151165539727
ko04978	Mineral absorption	9/722	40/7206	0.0154099740044
ko04141	Protein processing in endoplasmic reticulum	9/722	184/7206	0.0173588517684
ko04960	Aldosterone-regulated sodium reabsorption	9/722	41/7206	0.0180450698378
ko04622	RIG-I-like receptor signaling pathway	1/722	62/7206	0.0185496622033
ko04610	Complement and coagulation cascades	2/722	79/7206	0.0219411755108
ko04660	T cell receptor signaling pathway	5/722	124/7206	0.022543846886
ko04210	Apoptosis	9/722	180/7206	0.0226992313158
ko00190	Oxidative phosphorylation	21/722	127/7206	0.0236605978554
ko05215	Prostate cancer	4/722	111/7206	0.0238882361954
ko04540	Gap junction	21/722	128/7206	0.0242819976392
ko04550	Signaling pathways regulating pluripotency of stem cells	8/722	165/7206	0.0247268954796
ko05222	Small cell lung cancer	3/722	89/7206	0.0319059077534
ko00051	Fructose and mannose metabolism	9/722	42/7206	0.0327001895445
ko01040	Biosynthesis of unsaturated fatty acids	6/722	25/7206	0.0334195105654
ko00030	Pentose phosphate pathway	7/722	32/7206	0.0358364898145
ko04976	Bile secretion	14/722	80/7206	0.0366674776031
ko00520	Amino sugar and nucleotide sugar metabolism	1/722	55/7206	0.0398156235137
ko05321	Inflammatory bowel disease (IBD)	1/722	56/7206	0.0405291746607
ko04620	Toll-like receptor signaling pathway	4/722	100/7206	0.0428836209398
ko04152	AMPK signaling pathway	24/722	161/7206	0.0453466004268
ko04145	Phagosome	24/722	162/7206	0.046483107943
ko04750	Inflammatory mediator regulation of TRP channels	19/722	122/7206	0.0470802265051
ko00710	Carbon fixation in photosynthetic organisms	6/722	27/7206	0.0471104334688
ko05323	Rheumatoid arthritis	15/722	89/7206	0.0475047721161
ko00562	Inositol phosphate metabolism	15/722	89/7206	0.0475047721161