ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	61/445	145/7206	1.43162970574e-36
ko03030	DNA replication	30/445	38/7206	6.32664514831e-30
ko04110	Cell cycle	52/445	145/7206	3.41462685184e-27
ko04111	Cell cycle - yeast	37/445	90/7206	5.16574206472e-22
ko03410	Base excision repair	21/445	38/7206	2.75114581363e-16
ko03430	Mismatch repair	16/445	22/7206	1.82657333234e-15
ko04113	Meiosis - yeast	26/445	70/7206	1.56803168345e-14
ko03460	Fanconi anemia pathway	20/445	51/7206	5.56776782015e-12
ko03420	Nucleotide excision repair	19/445	46/7206	6.35077412722e-12
ko00240	Pyrimidine metabolism	28/445	110/7206	5.80770397439e-11
ko03440	Homologous recombination	16/445	41/7206	8.42803904389e-10
ko03013	RNA transport	33/445	166/7206	1.28422088412e-09
ko04144	Endocytosis	1/445	342/7206	1.08048804859e-08
ko03015	mRNA surveillance pathway	21/445	93/7206	1.45877400989e-07
ko04015	Rap1 signaling pathway	2/445	278/7206	5.28118874769e-06
ko04062	Chemokine signaling pathway	1/445	201/7206	7.11169632301e-05
ko05010	Alzheimer's disease	1/445	202/7206	7.27945002001e-05
ko04010	MAPK signaling pathway	5/445	321/7206	7.42336929763e-05
ko04060	Cytokine-cytokine receptor interaction	1/445	191/7206	0.000100966233738
ko04114	Oocyte meiosis	21/445	139/7206	0.000110976743325
ko05166	HTLV-I infection	35/445	292/7206	0.000149773704755
ko04024	cAMP signaling pathway	4/445	279/7206	0.000183698930821
ko04014	Ras signaling pathway	4/445	279/7206	0.000183698930821
ko03008	Ribosome biogenesis in eukaryotes	14/445	79/7206	0.000291621037919
ko04723	Retrograde endocannabinoid signaling	1/445	175/7206	0.000332952360909
ko00230	Purine metabolism	25/445	194/7206	0.000393454287095
ko04120	Ubiquitin mediated proteolysis	20/445	138/7206	0.000424179402286
ko04218	Cellular senescence	23/445	177/7206	0.000662467738232
ko04072	Phospholipase D signaling pathway	2/445	197/7206	0.000736388547639
ko04724	Glutamatergic synapse	1/445	152/7206	0.00102140183709
ko05160	Hepatitis C	1/445	153/7206	0.00102279617452
ko05012	Parkinson's disease	1/445	155/7206	0.00104085516093
ko03050	Proteasome	10/445	54/7206	0.00149318850956
ko04142	Lysosome	1/445	151/7206	0.00159674753585
ko05222	Small cell lung cancer	13/445	89/7206	0.00300605592666
ko04380	Osteoclast differentiation	1/445	134/7206	0.00320415725651
ko04726	Serotonergic synapse	1/445	137/7206	0.00332418190716
ko04022	cGMP-PKG signaling pathway	4/445	216/7206	0.00378087957902
ko04810	Regulation of actin cytoskeleton	6/445	264/7206	0.00397076917241
ko04725	Cholinergic synapse	2/445	160/7206	0.0042106454914
ko04071	Sphingolipid signaling pathway	2/445	162/7206	0.00428636834228
ko04611	Platelet activation	2/445	163/7206	0.00434828197914
ko05145	Toxoplasmosis	1/445	126/7206	0.00465893309695
ko00190	Oxidative phosphorylation	1/445	127/7206	0.00466220063081
ko03010	Ribosome	1/445	129/7206	0.00473219861014
ko05142	Chagas disease (American trypanosomiasis)	1/445	130/7206	0.00479943450206
ko04514	Cell adhesion molecules (CAMs)	1/445	130/7206	0.00479943450206
ko04141	Protein processing in endoplasmic reticulum	3/445	184/7206	0.00485449134807
ko04915	Estrogen signaling pathway	1/445	131/7206	0.00488858114903
ko04921	Oxytocin signaling pathway	4/445	209/7206	0.00523142184593
ko04914	Progesterone-mediated oocyte maturation	14/445	104/7206	0.00579305020819
ko04270	Vascular smooth muscle contraction	2/445	154/7206	0.0060229911377
ko04668	TNF signaling pathway	1/445	120/7206	0.00678185778849
ko04066	HIF-1 signaling pathway	1/445	123/7206	0.00693066909526
ko04261	Adrenergic signaling in cardiomyocytes	4/445	205/7206	0.00732013551049
ko03020	RNA polymerase	6/445	29/7206	0.0075425807608
ko04910	Insulin signaling pathway	3/445	172/7206	0.00952562899259
ko04911	Insulin secretion	1/445	117/7206	0.0101422923117
ko04140	Autophagy - animal	3/445	164/7206	0.0132006179412
ko05164	Influenza A	3/445	167/7206	0.0134218303731
ko04727	GABAergic synapse	1/445	110/7206	0.0146075006813
ko05032	Morphine addiction	1/445	110/7206	0.0146075006813
ko05206	MicroRNAs in cancer	19/445	177/7206	0.0166399965621
ko05231	Choline metabolism in cancer	2/445	134/7206	0.0171509168006
ko04933	AGE-RAGE signaling pathway in diabetic complications	2/445	135/7206	0.0172879513297
ko04713	Circadian entrainment	2/445	136/7206	0.0174802045749
ko03018	RNA degradation	11/445	84/7206	0.0182959208097
ko05152	Tuberculosis	4/445	187/7206	0.0193126825535
ko04925	Aldosterone synthesis and secretion	1/445	105/7206	0.021650148479
ko04371	Apelin signaling pathway	4/445	177/7206	0.0254914629173
ko05169	Epstein-Barr virus infection	21/445	206/7206	0.0258489952766
ko05168	Herpes simplex infection	19/445	182/7206	0.0269344234951
ko05211	Renal cell carcinoma	1/445	96/7206	0.0302560165504
ko00670	One carbon pool by folate	4/445	20/7206	0.0315645548505
ko04750	Inflammatory mediator regulation of TRP channels	2/445	122/7206	0.034338043163
ko04660	T cell receptor signaling pathway	2/445	124/7206	0.0352063088996
ko04917	Prolactin signaling pathway	1/445	87/7206	0.0431888155343
ko04146	Peroxisome	1/445	89/7206	0.0434844050206
ko05323	Rheumatoid arthritis	1/445	89/7206	0.0434844050206
ko04728	Dopaminergic synapse	5/445	185/7206	0.0437544706073
ko04150	mTOR signaling pathway	5/445	184/7206	0.0437644928829
ko04115	p53 signaling pathway	9/445	74/7206	0.0462388381502