ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	150/865	423/7206	7.01822398874e-39
ko05033	Nicotine addiction	43/865	56/7206	4.0639936162e-29
ko04724	Glutamatergic synapse	71/865	152/7206	6.53798887605e-27
ko05032	Morphine addiction	56/865	110/7206	9.10991208051e-24
ko04727	GABAergic synapse	55/865	110/7206	7.23731667591e-23
ko04713	Circadian entrainment	60/865	136/7206	2.70767730793e-21
ko04728	Dopaminergic synapse	66/865	185/7206	2.07260690614e-17
ko04725	Cholinergic synapse	60/865	160/7206	4.10207863947e-17
ko04723	Retrograde endocannabinoid signaling	62/865	175/7206	2.99496432954e-16
ko04020	Calcium signaling pathway	77/865	265/7206	2.18683998175e-14
ko04726	Serotonergic synapse	48/865	137/7206	1.22492082968e-12
ko04911	Insulin secretion	42/865	117/7206	1.30439445565e-11
ko04744	Phototransduction	21/865	36/7206	3.49876788249e-11
ko04742	Taste transduction	28/865	61/7206	4.20497763191e-11
ko04024	cAMP signaling pathway	72/865	279/7206	9.79367173748e-11
ko04721	Synaptic vesicle cycle	32/865	80/7206	1.46704858497e-10
ko04921	Oxytocin signaling pathway	58/865	209/7206	3.48503633283e-10
ko04740	Olfactory transduction	31/865	80/7206	7.32079544645e-10
ko05031	Amphetamine addiction	33/865	91/7206	1.55942856128e-09
ko04970	Salivary secretion	33/865	95/7206	5.51997357886e-09
ko04720	Long-term potentiation	31/865	99/7206	2.427572926e-07
ko04261	Adrenergic signaling in cardiomyocytes	50/865	205/7206	5.53849898442e-07
ko04971	Gastric acid secretion	30/865	98/7206	6.55237616552e-07
ko05030	Cocaine addiction	24/865	73/7206	2.10460291591e-06
ko05203	Viral carcinogenesis	11/865	277/7206	3.07584657109e-06
ko04730	Long-term depression	24/865	78/7206	7.77210441892e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	23/865	74/7206	9.94637274764e-06
ko05322	Systemic lupus erythematosus	3/865	151/7206	1.09399590057e-05
ko04514	Cell adhesion molecules (CAMs)	33/865	130/7206	2.67202230315e-05
ko04972	Pancreatic secretion	29/865	111/7206	4.13062881581e-05
ko04120	Ubiquitin mediated proteolysis	3/865	138/7206	5.02882226945e-05
ko03013	RNA transport	5/865	166/7206	5.2751383659e-05
ko04745	Phototransduction - fly	14/865	38/7206	6.96578206137e-05
ko04022	cGMP-PKG signaling pathway	46/865	216/7206	7.31029538508e-05
ko04010	MAPK signaling pathway	62/865	321/7206	0.000101473886265
ko04924	Renin secretion	23/865	86/7206	0.000153975138009
ko04925	Aldosterone synthesis and secretion	26/865	105/7206	0.000226725336209
ko05164	Influenza A	6/865	167/7206	0.000243434069391
ko04964	Proximal tubule bicarbonate reclamation	11/865	29/7206	0.000311349564108
ko05162	Measles	3/865	120/7206	0.000314996655238
ko04110	Cell cycle	5/865	145/7206	0.00042562077021
ko04750	Inflammatory mediator regulation of TRP channels	28/865	122/7206	0.000602783775201
ko04014	Ras signaling pathway	53/865	279/7206	0.000650872435297
ko03008	Ribosome biogenesis in eukaryotes	1/865	79/7206	0.000752786767894
ko04070	Phosphatidylinositol signaling system	26/865	112/7206	0.00100610972064
ko04141	Protein processing in endoplasmic reticulum	9/865	184/7206	0.00122965670099
ko04976	Bile secretion	20/865	80/7206	0.0013590889979
ko04540	Gap junction	28/865	128/7206	0.00137765035588
ko04260	Cardiac muscle contraction	23/865	98/7206	0.00139846982797
ko05169	Epstein-Barr virus infection	11/865	206/7206	0.00151600314764
ko05168	Herpes simplex infection	9/865	182/7206	0.00166196548254
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/865	59/7206	0.00170137338777
ko04974	Protein digestion and absorption	22/865	96/7206	0.00229293969972
ko04960	Aldosterone-regulated sodium reabsorption	12/865	41/7206	0.00237569504657
ko04711	Circadian rhythm - fly	6/865	13/7206	0.00238936299738
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/865	79/7206	0.00251861042833
ko04072	Phospholipase D signaling pathway	38/865	197/7206	0.00254893056382
ko05161	Hepatitis B	9/865	173/7206	0.00411391252018
ko05166	HTLV-I infection	20/865	292/7206	0.00423834336734
ko04630	Jak-STAT signaling pathway	6/865	132/7206	0.00623020604339
ko04218	Cellular senescence	10/865	177/7206	0.00666511544738
ko05130	Pathogenic Escherichia coli infection	2/865	77/7206	0.00708450273823
ko04612	Antigen processing and presentation	2/865	77/7206	0.00708450273823
ko04360	Axon guidance	41/865	233/7206	0.0102222233605
ko03018	RNA degradation	3/865	84/7206	0.0109800681688
ko05220	Chronic myeloid leukemia	3/865	85/7206	0.0110001755239
ko05215	Prostate cancer	5/865	111/7206	0.0115030157698
ko00520	Amino sugar and nucleotide sugar metabolism	1/865	55/7206	0.0118056549563
ko04270	Vascular smooth muscle contraction	29/865	154/7206	0.0118548524609
ko04060	Cytokine-cytokine receptor interaction	12/865	191/7206	0.0124948492784
ko04217	Necroptosis	11/865	178/7206	0.0136624039969
ko04710	Circadian rhythm	11/865	43/7206	0.0147487333908
ko04626	Plant-pathogen interaction	6/865	18/7206	0.015264350779
ko05211	Renal cell carcinoma	4/865	96/7206	0.0162824108923
ko05016	Huntington's disease	15/865	215/7206	0.0188349048287
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/865	14/7206	0.0194731813317
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/865	182/7206	0.0204904173995
ko04142	Lysosome	9/865	151/7206	0.0217138625199
ko04610	Complement and coagulation cascades	3/865	79/7206	0.0219568671751
ko04978	Mineral absorption	10/865	40/7206	0.0231613642807
ko04621	NOD-like receptor signaling pathway	10/865	157/7206	0.0251178855504
ko00260	Glycine, serine and threonine metabolism	1/865	48/7206	0.0255737465685
ko05219	Bladder cancer	1/865	48/7206	0.0255737465685
ko00330	Arginine and proline metabolism	2/865	61/7206	0.0290932623512
ko05140	Leishmaniasis	3/865	75/7206	0.0304154901128
ko04146	Peroxisome	4/865	89/7206	0.0308044100237
ko04145	Phagosome	11/865	162/7206	0.0373256910253
ko00071	Fatty acid degradation	1/865	45/7206	0.0374836741999
ko00620	Pyruvate metabolism	1/865	46/7206	0.0378347409461
ko03420	Nucleotide excision repair	1/865	46/7206	0.0378347409461
ko05414	Dilated cardiomyopathy	21/865	112/7206	0.0384512213008
ko01200	Carbon metabolism	8/865	128/7206	0.0397244843259
ko05212	Pancreatic cancer	4/865	83/7206	0.0407496066276
ko04113	Meiosis - yeast	3/865	70/7206	0.0419339943177
ko04214	Apoptosis - fly	3/865	72/7206	0.0426093005649
ko01212	Fatty acid metabolism	2/865	60/7206	0.0427301213949
ko00310	Lysine degradation	3/865	73/7206	0.0435405182739
ko05205	Proteoglycans in cancer	22/865	271/7206	0.0451602869851
ko04371	Apelin signaling pathway	30/865	177/7206	0.0461353665364
ko04916	Melanogenesis	25/865	142/7206	0.0490660008132