ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	32/404	56/7206	3.47553730063e-26
ko04724	Glutamatergic synapse	46/404	152/7206	2.18450010034e-22
ko04080	Neuroactive ligand-receptor interaction	72/404	423/7206	2.1227059386e-18
ko04723	Retrograde endocannabinoid signaling	43/404	175/7206	3.5189217929e-17
ko05032	Morphine addiction	34/404	110/7206	4.18075026201e-17
ko04727	GABAergic synapse	33/404	110/7206	3.3674267166e-16
ko04728	Dopaminergic synapse	39/404	185/7206	2.5281252749e-13
ko04713	Circadian entrainment	31/404	136/7206	9.39220968169e-12
ko04020	Calcium signaling pathway	43/404	265/7206	1.46675461717e-10
ko05031	Amphetamine addiction	23/404	91/7206	5.49106096188e-10
ko04024	cAMP signaling pathway	43/404	279/7206	7.8781169274e-10
ko05030	Cocaine addiction	20/404	73/7206	1.61654545895e-09
ko04911	Insulin secretion	25/404	117/7206	4.30805163414e-09
ko04721	Synaptic vesicle cycle	20/404	80/7206	9.2263089401e-09
ko04010	MAPK signaling pathway	44/404	321/7206	2.62838479533e-08
ko04925	Aldosterone synthesis and secretion	21/404	105/7206	2.54176693997e-07
ko04720	Long-term potentiation	20/404	99/7206	4.15187929825e-07
ko04725	Cholinergic synapse	26/404	160/7206	7.24068134644e-07
ko04261	Adrenergic signaling in cardiomyocytes	30/404	205/7206	1.02494398797e-06
ko04921	Oxytocin signaling pathway	30/404	209/7206	1.55297148009e-06
ko04742	Taste transduction	14/404	61/7206	4.82834651037e-06
ko04726	Serotonergic synapse	22/404	137/7206	6.40712373179e-06
ko04022	cGMP-PKG signaling pathway	29/404	216/7206	1.21849734998e-05
ko04072	Phospholipase D signaling pathway	27/404	197/7206	1.25884643325e-05
ko04970	Salivary secretion	17/404	95/7206	1.7115876789e-05
ko04915	Estrogen signaling pathway	20/404	131/7206	3.60955953162e-05
ko04514	Cell adhesion molecules (CAMs)	19/404	130/7206	0.000103472325279
ko04060	Cytokine-cytokine receptor interaction	1/404	191/7206	0.000333622798108
ko04972	Pancreatic secretion	16/404	111/7206	0.000423073457985
ko05231	Choline metabolism in cancer	18/404	134/7206	0.000456372940575
ko05414	Dilated cardiomyopathy	16/404	112/7206	0.000468804154336
ko05203	Viral carcinogenesis	4/404	277/7206	0.000731575760859
ko05014	Amyotrophic lateral sclerosis (ALS)	12/404	74/7206	0.000756227733697
ko04730	Long-term depression	12/404	78/7206	0.00122198109081
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/404	79/7206	0.00136968523879
ko04930	Type II diabetes mellitus	9/404	54/7206	0.00280268577607
ko05168	Herpes simplex infection	2/404	182/7206	0.00298774097636
ko04912	GnRH signaling pathway	15/404	122/7206	0.00406781432884
ko04666	Fc gamma R-mediated phagocytosis	15/404	122/7206	0.00406781432884
ko04740	Olfactory transduction	11/404	80/7206	0.00475338182336
ko04110	Cell cycle	1/404	145/7206	0.00504995325363
ko04540	Gap junction	15/404	128/7206	0.0057054512449
ko04270	Vascular smooth muscle contraction	17/404	154/7206	0.00680901640328
ko04145	Phagosome	2/404	162/7206	0.00867341335531
ko04070	Phosphatidylinositol signaling system	13/404	112/7206	0.0110649963324
ko04260	Cardiac muscle contraction	12/404	98/7206	0.0117005914369
ko04621	NOD-like receptor signaling pathway	2/404	157/7206	0.0125289150889
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/404	182/7206	0.0134186885036
ko04141	Protein processing in endoplasmic reticulum	3/404	184/7206	0.0135976697846
ko04144	Endocytosis	30/404	342/7206	0.0151605410297
ko04670	Leukocyte transendothelial migration	2/404	151/7206	0.017986253497
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	5/404	28/7206	0.0182294637083
ko04360	Axon guidance	22/404	233/7206	0.019106996331
ko05034	Alcoholism	22/404	238/7206	0.0205403370515
ko00512	Mucin type O-glycan biosynthesis	5/404	29/7206	0.021043600781
ko05205	Proteoglycans in cancer	7/404	271/7206	0.0220253297031
ko04971	Gastric acid secretion	11/404	98/7206	0.0240935628827
ko05410	Hypertrophic cardiomyopathy (HCM)	11/404	100/7206	0.0267230841102
ko04350	TGF-beta signaling pathway	1/404	103/7206	0.0303246205148
ko04015	Rap1 signaling pathway	24/404	278/7206	0.0324374642467
ko04014	Ras signaling pathway	24/404	279/7206	0.0329688873995
ko05202	Transcriptional misregulation in cancer	4/404	188/7206	0.0349780896961
ko00604	Glycosphingolipid biosynthesis - ganglio series	3/404	14/7206	0.0401199698776
ko05169	Epstein-Barr virus infection	5/404	206/7206	0.0443183270383
ko04217	Necroptosis	4/404	178/7206	0.0467079607361
ko04750	Inflammatory mediator regulation of TRP channels	12/404	122/7206	0.0471212329334
ko04142	Lysosome	3/404	151/7206	0.0482202346277
ko00515	Mannose type O-glycan biosynthesis	4/404	25/7206	0.0483619858821
ko00190	Oxidative phosphorylation	2/404	127/7206	0.0485515069382
ko01200	Carbon metabolism	2/404	128/7206	0.0490136228431