ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	154/917	423/7206	2.71590949011e-38
ko05033	Nicotine addiction	48/917	56/7206	1.82495609125e-35
ko04724	Glutamatergic synapse	82/917	152/7206	5.85158198777e-35
ko04727	GABAergic synapse	64/917	110/7206	4.95236611131e-30
ko05032	Morphine addiction	63/917	110/7206	4.9503480535e-29
ko04713	Circadian entrainment	65/917	136/7206	5.86935168797e-24
ko04723	Retrograde endocannabinoid signaling	73/917	175/7206	2.55875781056e-22
ko04728	Dopaminergic synapse	75/917	185/7206	5.36444541214e-22
ko04725	Cholinergic synapse	65/917	160/7206	3.01802397336e-19
ko04744	Phototransduction	27/917	36/7206	1.43150577136e-17
ko04024	cAMP signaling pathway	86/917	279/7206	4.06451064987e-16
ko04721	Synaptic vesicle cycle	40/917	80/7206	4.78286780686e-16
ko04742	Taste transduction	34/917	61/7206	1.06709833563e-15
ko04911	Insulin secretion	48/917	117/7206	1.03833489847e-14
ko04726	Serotonergic synapse	52/917	137/7206	3.53405365929e-14
ko04020	Calcium signaling pathway	78/917	265/7206	2.5095286969e-13
ko04921	Oxytocin signaling pathway	63/917	209/7206	1.29339411733e-11
ko05031	Amphetamine addiction	36/917	91/7206	8.27231755606e-11
ko04261	Adrenergic signaling in cardiomyocytes	59/917	205/7206	6.99978162263e-10
ko04720	Long-term potentiation	36/917	99/7206	1.31959243039e-09
ko05030	Cocaine addiction	29/917	73/7206	5.16303663821e-09
ko04740	Olfactory transduction	29/917	80/7206	5.82188269113e-08
ko04970	Salivary secretion	32/917	95/7206	9.00299098452e-08
ko03040	Spliceosome	1/917	145/7206	9.10597228919e-08
ko05203	Viral carcinogenesis	10/917	277/7206	1.74298008456e-07
ko04925	Aldosterone synthesis and secretion	33/917	105/7206	3.62414381155e-07
ko04010	MAPK signaling pathway	71/917	321/7206	1.84419954011e-06
ko04514	Cell adhesion molecules (CAMs)	36/917	130/7206	3.57606417246e-06
ko04972	Pancreatic secretion	32/917	111/7206	4.70181846823e-06
ko04060	Cytokine-cytokine receptor interaction	6/917	191/7206	7.28045422846e-06
ko03013	RNA transport	5/917	166/7206	1.70190819649e-05
ko05164	Influenza A	5/917	167/7206	1.70396963155e-05
ko04072	Phospholipase D signaling pathway	47/917	197/7206	1.70820484254e-05
ko05322	Systemic lupus erythematosus	4/917	151/7206	1.97405464845e-05
ko04971	Gastric acid secretion	28/917	98/7206	2.24926725459e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/917	74/7206	2.60984535879e-05
ko04022	cGMP-PKG signaling pathway	49/917	216/7206	4.15877239325e-05
ko04621	NOD-like receptor signaling pathway	5/917	157/7206	4.98523185023e-05
ko04260	Cardiac muscle contraction	27/917	98/7206	8.21265407956e-05
ko04120	Ubiquitin mediated proteolysis	4/917	138/7206	8.5429367825e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/917	79/7206	0.000102230037916
ko04745	Phototransduction - fly	14/917	38/7206	0.000132562948858
ko04070	Phosphatidylinositol signaling system	29/917	112/7206	0.000142136027194
ko04110	Cell cycle	5/917	145/7206	0.000207406793058
ko04730	Long-term depression	22/917	78/7206	0.000217489236997
ko05168	Herpes simplex infection	8/917	182/7206	0.000258668318149
ko05205	Proteoglycans in cancer	16/917	271/7206	0.000262829986783
ko04141	Protein processing in endoplasmic reticulum	9/917	184/7206	0.000471611114523
ko04610	Complement and coagulation cascades	1/917	79/7206	0.000492098116227
ko03008	Ribosome biogenesis in eukaryotes	1/917	79/7206	0.000492098116227
ko05169	Epstein-Barr virus infection	11/917	206/7206	0.000613870203461
ko05162	Measles	4/917	120/7206	0.000748089808
ko04612	Antigen processing and presentation	1/917	77/7206	0.00077344877019
ko04630	Jak-STAT signaling pathway	5/917	132/7206	0.00082365293149
ko05414	Dilated cardiomyopathy	27/917	112/7206	0.000833788707903
ko05161	Hepatitis B	9/917	173/7206	0.00163214011866
ko04064	NF-kappa B signaling pathway	3/917	96/7206	0.00183876893421
ko04964	Proximal tubule bicarbonate reclamation	10/917	29/7206	0.00216711973719
ko04924	Renin secretion	21/917	86/7206	0.00280980402744
ko04930	Type II diabetes mellitus	15/917	54/7206	0.0029485723082
ko04540	Gap junction	28/917	128/7206	0.00310944513693
ko04966	Collecting duct acid secretion	9/917	26/7206	0.00348285878048
ko05140	Leishmaniasis	2/917	75/7206	0.00465562358668
ko04915	Estrogen signaling pathway	28/917	131/7206	0.00503043919846
ko04976	Bile secretion	19/917	80/7206	0.00607884275459
ko04014	Ras signaling pathway	51/917	279/7206	0.00757957473513
ko00480	Glutathione metabolism	1/917	55/7206	0.00777406464454
ko04750	Inflammatory mediator regulation of TRP channels	26/917	122/7206	0.00843711599373
ko04710	Circadian rhythm	12/917	43/7206	0.00876005037917
ko05016	Huntington's disease	15/917	215/7206	0.00900977603546
ko05034	Alcoholism	44/917	238/7206	0.00977839004165
ko04062	Chemokine signaling pathway	38/917	201/7206	0.0129815471691
ko04640	Hematopoietic cell lineage	2/917	64/7206	0.0138934444371
ko04146	Peroxisome	4/917	89/7206	0.0154436788292
ko04360	Axon guidance	42/917	233/7206	0.0164207924962
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/917	59/7206	0.0171995902315
ko04140	Autophagy - animal	11/917	164/7206	0.0172600316874
ko04711	Circadian rhythm - fly	5/917	13/7206	0.0176276379125
ko05215	Prostate cancer	6/917	111/7206	0.0203276322217
ko05410	Hypertrophic cardiomyopathy (HCM)	21/917	100/7206	0.0218399223236
ko04371	Apelin signaling pathway	33/917	177/7206	0.0218413784768
ko04210	Apoptosis	13/917	180/7206	0.023062935232
ko00562	Inositol phosphate metabolism	19/917	89/7206	0.0232634176198
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/917	182/7206	0.0234342213512
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/917	14/7206	0.024608746211
ko00620	Pyruvate metabolism	1/917	46/7206	0.0250222994525
ko03420	Nucleotide excision repair	1/917	46/7206	0.0250222994525
ko05231	Choline metabolism in cancer	26/917	134/7206	0.0253610559507
ko00270	Cysteine and methionine metabolism	1/917	47/7206	0.0254254456461
ko03320	PPAR signaling pathway	3/917	69/7206	0.0295999499995
ko04217	Necroptosis	13/917	178/7206	0.0296197060268
ko05145	Toxoplasmosis	8/917	126/7206	0.029981528007
ko05166	HTLV-I infection	25/917	292/7206	0.0309374250126
ko04150	mTOR signaling pathway	14/917	184/7206	0.0330164821783
ko05110	Vibrio cholerae infection	14/917	63/7206	0.0341560722582
ko03022	Basal transcription factors	1/917	44/7206	0.0376072891401
ko04510	Focal adhesion	20/917	240/7206	0.0381770128577
ko05144	Malaria	1/917	45/7206	0.0389730075919
ko00071	Fatty acid degradation	1/917	45/7206	0.0389730075919
ko04923	Regulation of lipolysis in adipocytes	16/917	77/7206	0.0390495144546
ko00280	Valine, leucine and isoleucine degradation	2/917	54/7206	0.0406135442196
ko05321	Inflammatory bowel disease (IBD)	2/917	56/7206	0.0413095933084
ko00240	Pyrimidine metabolism	7/917	110/7206	0.0429409615404
ko00230	Purine metabolism	34/917	194/7206	0.0487545351666