ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	79/592	145/7206	1.48013855395e-48
ko03008	Ribosome biogenesis in eukaryotes	46/592	79/7206	3.27151158688e-30
ko03013	RNA transport	60/592	166/7206	1.23738725406e-24
ko03030	DNA replication	27/592	38/7206	1.43872831588e-21
ko04110	Cell cycle	50/592	145/7206	1.22937410054e-19
ko04111	Cell cycle - yeast	35/592	90/7206	5.99244349125e-16
ko00240	Pyrimidine metabolism	36/592	110/7206	1.19132164091e-13
ko03430	Mismatch repair	14/592	22/7206	9.48797473005e-11
ko03420	Nucleotide excision repair	20/592	46/7206	1.05308678513e-10
ko03020	RNA polymerase	15/592	29/7206	1.15575329275e-09
ko04113	Meiosis - yeast	23/592	70/7206	3.20917941308e-09
ko03410	Base excision repair	16/592	38/7206	1.4190101542e-08
ko03015	mRNA surveillance pathway	26/592	93/7206	1.4327924409e-08
ko04024	cAMP signaling pathway	2/592	279/7206	1.96828800684e-08
ko04022	cGMP-PKG signaling pathway	1/592	216/7206	2.27479802012e-07
ko04144	Endocytosis	6/592	342/7206	2.82386789511e-07
ko00230	Purine metabolism	38/592	194/7206	3.42288377722e-07
ko05322	Systemic lupus erythematosus	31/592	151/7206	1.30648927598e-06
ko04060	Cytokine-cytokine receptor interaction	1/592	191/7206	2.74350705771e-06
ko03018	RNA degradation	20/592	84/7206	1.02080523002e-05
ko03440	Homologous recombination	13/592	41/7206	1.38947618631e-05
ko03460	Fanconi anemia pathway	14/592	51/7206	4.05578744826e-05
ko04270	Vascular smooth muscle contraction	1/592	154/7206	4.10002191528e-05
ko05012	Parkinson's disease	1/592	155/7206	4.14356088131e-05
ko04261	Adrenergic signaling in cardiomyocytes	3/592	205/7206	4.5214734359e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/592	182/7206	4.8247166684e-05
ko04724	Glutamatergic synapse	1/592	152/7206	6.42561874439e-05
ko04062	Chemokine signaling pathway	3/592	201/7206	6.62934437623e-05
ko04723	Retrograde endocannabinoid signaling	2/592	175/7206	6.75120436459e-05
ko03050	Proteasome	14/592	54/7206	8.08128404436e-05
ko05169	Epstein-Barr virus infection	33/592	206/7206	0.000157585433402
ko04380	Osteoclast differentiation	1/592	134/7206	0.000196755950506
ko04713	Circadian entrainment	1/592	136/7206	0.000200181157645
ko04725	Cholinergic synapse	2/592	160/7206	0.000207902033229
ko04810	Regulation of actin cytoskeleton	7/592	264/7206	0.000224417838242
ko04514	Cell adhesion molecules (CAMs)	1/592	130/7206	0.000291374720902
ko04510	Focal adhesion	6/592	240/7206	0.000292898471152
ko05203	Viral carcinogenesis	40/592	277/7206	0.000461068125527
ko04010	MAPK signaling pathway	11/592	321/7206	0.000562045670118
ko04921	Oxytocin signaling pathway	5/592	209/7206	0.000747789693362
ko04611	Platelet activation	3/592	163/7206	0.00079942131851
ko04014	Ras signaling pathway	9/592	279/7206	0.00080011913635
ko04728	Dopaminergic synapse	4/592	185/7206	0.000947409991653
ko04015	Rap1 signaling pathway	9/592	278/7206	0.00109982148721
ko04371	Apelin signaling pathway	4/592	177/7206	0.00130114471647
ko04931	Insulin resistance	2/592	137/7206	0.00135121574995
ko04726	Serotonergic synapse	2/592	137/7206	0.00135121574995
ko04727	GABAergic synapse	1/592	110/7206	0.00136887792282
ko05032	Morphine addiction	1/592	110/7206	0.00136887792282
ko04972	Pancreatic secretion	1/592	111/7206	0.00137729043004
ko04360	Axon guidance	7/592	233/7206	0.00149167423254
ko04621	NOD-like receptor signaling pathway	3/592	157/7206	0.00168032025398
ko04925	Aldosterone synthesis and secretion	1/592	105/7206	0.00201040972615
ko04670	Leukocyte transendothelial migration	3/592	151/7206	0.00233250272818
ko05034	Alcoholism	33/592	238/7206	0.00250242261185
ko05152	Tuberculosis	5/592	187/7206	0.00270466774628
ko04620	Toll-like receptor signaling pathway	1/592	100/7206	0.00294918588793
ko04668	TNF signaling pathway	2/592	120/7206	0.00390777628356
ko04912	GnRH signaling pathway	2/592	122/7206	0.00399505470694
ko04750	Inflammatory mediator regulation of TRP channels	2/592	122/7206	0.00399505470694
ko04650	Natural killer cell mediated cytotoxicity	1/592	97/7206	0.00438241723385
ko05146	Amoebiasis	1/592	99/7206	0.00459085279254
ko04072	Phospholipase D signaling pathway	6/592	197/7206	0.00521012260579
ko05031	Amphetamine addiction	1/592	91/7206	0.00633528712418
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/592	92/7206	0.00639993507422
ko04530	Tight junction	8/592	228/7206	0.0065183379598
ko04142	Lysosome	4/592	151/7206	0.00681229230739
ko04218	Cellular senescence	25/592	177/7206	0.00766592197452
ko04070	Phosphatidylinositol signaling system	2/592	112/7206	0.0081489469592
ko03022	Basal transcription factors	9/592	44/7206	0.00837983486185
ko04540	Gap junction	3/592	128/7206	0.00893697011806
ko03060	Protein export	6/592	23/7206	0.00901004036723
ko05142	Chagas disease (American trypanosomiasis)	3/592	130/7206	0.0090242137187
ko04915	Estrogen signaling pathway	3/592	131/7206	0.00914000134194
ko04918	Thyroid hormone synthesis	1/592	86/7206	0.00924874991341
ko04630	Jak-STAT signaling pathway	3/592	132/7206	0.00930455053233
ko05133	Pertussis	1/592	87/7206	0.00933448024757
ko04662	B cell receptor signaling pathway	1/592	88/7206	0.00949340876619
ko04659	Th17 cell differentiation	2/592	106/7206	0.0114478073018
ko05166	HTLV-I infection	36/592	292/7206	0.0121129713227
ko05145	Toxoplasmosis	3/592	126/7206	0.0127718392202
ko04722	Neurotrophin signaling pathway	5/592	160/7206	0.012872300988
ko04145	Phagosome	5/592	162/7206	0.0129984291806
ko04151	PI3K-Akt signaling pathway	19/592	390/7206	0.0132479002102
ko05100	Bacterial invasion of epithelial cells	2/592	99/7206	0.0161267242714
ko00564	Glycerophospholipid metabolism	2/592	99/7206	0.0161267242714
ko04666	Fc gamma R-mediated phagocytosis	3/592	122/7206	0.0181006035115
ko04115	p53 signaling pathway	12/592	74/7206	0.0183285974265
ko05168	Herpes simplex infection	24/592	182/7206	0.0192354483885
ko05140	Leishmaniasis	1/592	75/7206	0.0196092866428
ko04730	Long-term depression	1/592	78/7206	0.0200673594311
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	1/592	79/7206	0.0205070450201
ko04658	Th1 and Th2 cell differentiation	2/592	96/7206	0.0230260551382
ko05231	Choline metabolism in cancer	4/592	134/7206	0.0245815443997
ko04933	AGE-RAGE signaling pathway in diabetic complications	4/592	135/7206	0.0249143086977
ko00970	Aminoacyl-tRNA biosynthesis	8/592	44/7206	0.0249886932262
ko04139	Mitophagy - yeast	7/592	37/7206	0.0287140074532
ko04071	Sphingolipid signaling pathway	6/592	162/7206	0.0297192549356
ko04146	Peroxisome	2/592	89/7206	0.0322277847548
ko00562	Inositol phosphate metabolism	2/592	89/7206	0.0322277847548
ko04922	Glucagon signaling pathway	4/592	128/7206	0.0331482357585
ko04066	HIF-1 signaling pathway	4/592	123/7206	0.044943658326
ko04660	T cell receptor signaling pathway	4/592	124/7206	0.0453959770337
ko04520	Adherens junction	3/592	103/7206	0.0458909044767
ko04910	Insulin signaling pathway	7/592	172/7206	0.0477212731811