ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 13/206 79/7206 2.92176363648e-07 ko04974 Protein digestion and absorption 13/206 96/7206 2.91170462003e-06 ko04610 Complement and coagulation cascades 9/206 79/7206 0.000389105759166 ko04976 Bile secretion 9/206 80/7206 0.000427758015339 ko04260 Cardiac muscle contraction 10/206 98/7206 0.000458005793688 ko04510 Focal adhesion 17/206 240/7206 0.000484262915744 ko01230 Biosynthesis of amino acids 8/206 85/7206 0.00283862750811 ko04144 Endocytosis 2/206 342/7206 0.00435049618613 ko04964 Proximal tubule bicarbonate reclamation 4/206 29/7206 0.00879541948211 ko01200 Carbon metabolism 9/206 128/7206 0.0108542872098 ko00030 Pentose phosphate pathway 4/206 32/7206 0.012460430112 ko00350 Tyrosine metabolism 4/206 33/7206 0.0138690959222 ko00910 Nitrogen metabolism 3/206 19/7206 0.0159132617398 ko00010 Glycolysis / Gluconeogenesis 6/206 74/7206 0.0187485242798 ko00630 Glyoxylate and dicarboxylate metabolism 4/206 38/7206 0.0224079766364 ko04977 Vitamin digestion and absorption 3/206 22/7206 0.0237567329755 ko05410 Hypertrophic cardiomyopathy (HCM) 7/206 100/7206 0.0240189645021 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 6/206 79/7206 0.0250420336441 ko04978 Mineral absorption 4/206 40/7206 0.0265512983989 ko04151 PI3K-Akt signaling pathway 19/206 390/7206 0.0267057268453 ko00220 Arginine biosynthesis 3/206 24/7206 0.029952437483 ko00983 Drug metabolism - other enzymes 4/206 42/7206 0.0311246039837 ko04514 Cell adhesion molecules (CAMs) 8/206 130/7206 0.0324207173923 ko00710 Carbon fixation in photosynthetic organisms 3/206 27/7206 0.0406804164987 ko04670 Leukocyte transendothelial migration 9/206 151/7206 0.0407226034781 ko05414 Dilated cardiomyopathy 7/206 112/7206 0.0409725717023 ko04060 Cytokine-cytokine receptor interaction 1/206 191/7206 0.0454523569434 ko05167 Kaposi's sarcoma-associated herpesvirus infection 1/206 191/7206 0.0454523569434 ko04072 Phospholipase D signaling pathway 1/206 197/7206 0.0466295687413 ko04080 Neuroactive ligand-receptor interaction 19/206 423/7206 0.0486830154582 ko04950 Maturity onset diabetes of the young 3/206 29/7206 0.0487667375858