ko pathway ratio_in_study ratio_in_pop p_value ko04744 Phototransduction 16/345 36/7206 1.64968315197e-12 ko04740 Olfactory transduction 18/345 80/7206 2.63036020296e-08 ko04727 GABAergic synapse 21/345 110/7206 3.95996964673e-08 ko04713 Circadian entrainment 23/345 136/7206 9.4322547109e-08 ko04724 Glutamatergic synapse 24/345 152/7206 1.8932997933e-07 ko05032 Morphine addiction 20/345 110/7206 1.95359468801e-07 ko04725 Cholinergic synapse 21/345 160/7206 2.22900377807e-05 ko05033 Nicotine addiction 11/345 56/7206 5.5194651946e-05 ko04080 Neuroactive ligand-receptor interaction 39/345 423/7206 8.10447770655e-05 ko04020 Calcium signaling pathway 28/345 265/7206 8.66370643527e-05 ko04710 Circadian rhythm 9/345 43/7206 0.000158033160468 ko04728 Dopaminergic synapse 21/345 185/7206 0.000291068117636 ko04921 Oxytocin signaling pathway 22/345 209/7206 0.000425987507907 ko04911 Insulin secretion 15/345 117/7206 0.000430285460395 ko04024 cAMP signaling pathway 27/345 279/7206 0.000458546518156 ko04742 Taste transduction 10/345 61/7206 0.000563750132341 ko04726 Serotonergic synapse 16/345 137/7206 0.000799509839093 ko04723 Retrograde endocannabinoid signaling 19/345 175/7206 0.000835671400587 ko05203 Viral carcinogenesis 3/345 277/7206 0.00131439106708 ko05031 Amphetamine addiction 11/345 91/7206 0.00392502957719 ko00680 Methane metabolism 6/345 34/7206 0.00496711022433 ko04971 Gastric acid secretion 11/345 98/7206 0.00690440874418 ko04720 Long-term potentiation 11/345 99/7206 0.00744526674192 ko00010 Glycolysis / Gluconeogenesis 9/345 74/7206 0.00841081409322 ko04745 Phototransduction - fly 6/345 38/7206 0.0086843208034 ko04022 cGMP-PKG signaling pathway 19/345 216/7206 0.00898932189594 ko04062 Chemokine signaling pathway 18/345 201/7206 0.0104950713793 ko04070 Phosphatidylinositol signaling system 12/345 112/7206 0.0110007008331 ko04964 Proximal tubule bicarbonate reclamation 5/345 29/7206 0.0112300943174 ko04960 Aldosterone-regulated sodium reabsorption 6/345 41/7206 0.0125460363736 ko04721 Synaptic vesicle cycle 9/345 80/7206 0.0137479919004 ko04120 Ubiquitin mediated proteolysis 1/345 138/7206 0.0147978759844 ko03040 Spliceosome 1/345 145/7206 0.0157657000416 ko00030 Pentose phosphate pathway 5/345 32/7206 0.0169439479149 ko04925 Aldosterone synthesis and secretion 11/345 105/7206 0.016990254448 ko04270 Vascular smooth muscle contraction 14/345 154/7206 0.019705227917 ko04711 Circadian rhythm - fly 3/345 13/7206 0.0217470047011 ko05166 HTLV-I infection 6/345 292/7206 0.0239491591647 ko05014 Amyotrophic lateral sclerosis (ALS) 8/345 74/7206 0.0244258783426 ko03013 RNA transport 2/345 166/7206 0.0251247190934 ko05164 Influenza A 2/345 167/7206 0.0253440224339 ko04371 Apelin signaling pathway 15/345 177/7206 0.0300274642219 ko00230 Purine metabolism 16/345 194/7206 0.0378477211221 ko00562 Inositol phosphate metabolism 9/345 89/7206 0.0383091784038 ko04978 Mineral absorption 5/345 40/7206 0.040647665029 ko04014 Ras signaling pathway 21/345 279/7206 0.0431928205389 ko04972 Pancreatic secretion 10/345 111/7206 0.0435048337935 ko04261 Adrenergic signaling in cardiomyocytes 16/345 205/7206 0.0461410734464 ko04970 Salivary secretion 9/345 95/7206 0.0466409630336 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/345 1/7206 0.047876769359 ko04110 Cell cycle 2/345 145/7206 0.048410452964 ko00830 Retinol metabolism 5/345 42/7206 0.0486703879458