ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 36/315 157/7206 5.5768206504e-17 ko04060 Cytokine-cytokine receptor interaction 39/315 191/7206 1.79771544314e-16 ko04380 Osteoclast differentiation 31/315 134/7206 7.17083390433e-15 ko04650 Natural killer cell mediated cytotoxicity 25/315 97/7206 2.35882693784e-13 ko05340 Primary immunodeficiency 14/315 30/7206 5.40378736309e-12 ko05164 Influenza A 30/315 167/7206 2.15074814323e-11 ko04660 T cell receptor signaling pathway 25/315 124/7206 8.26748527091e-11 ko04064 NF-kappa B signaling pathway 22/315 96/7206 8.44011500182e-11 ko05145 Toxoplasmosis 25/315 126/7206 1.19044619893e-10 ko05140 Leishmaniasis 19/315 75/7206 2.67832280225e-10 ko05152 Tuberculosis 30/315 187/7206 3.96337485957e-10 ko05162 Measles 23/315 120/7206 1.3909404061e-09 ko05330 Allograft rejection 11/315 24/7206 1.40567262145e-09 ko05150 Staphylococcus aureus infection 13/315 36/7206 1.55114014227e-09 ko04620 Toll-like receptor signaling pathway 20/315 100/7206 7.90832542497e-09 ko05321 Inflammatory bowel disease (IBD) 15/315 56/7206 9.32495457442e-09 ko04217 Necroptosis 27/315 178/7206 1.09578545466e-08 ko05168 Herpes simplex infection 27/315 182/7206 1.78623928546e-08 ko04662 B cell receptor signaling pathway 18/315 88/7206 3.12386610923e-08 ko05133 Pertussis 17/315 87/7206 1.54322587289e-07 ko05320 Autoimmune thyroid disease 10/315 29/7206 2.11008551516e-07 ko05144 Malaria 12/315 45/7206 3.09669741629e-07 ko05332 Graft-versus-host disease 8/315 18/7206 3.6408390601e-07 ko04062 Chemokine signaling pathway 26/315 201/7206 5.44622748982e-07 ko04659 Th17 cell differentiation 18/315 106/7206 6.07703697708e-07 ko04658 Th1 and Th2 cell differentiation 17/315 96/7206 6.78983601951e-07 ko05167 Kaposi's sarcoma-associated herpesvirus infection 24/315 191/7206 2.55481235646e-06 ko04630 Jak-STAT signaling pathway 19/315 132/7206 3.94723124493e-06 ko04610 Complement and coagulation cascades 14/315 79/7206 6.60064666059e-06 ko04622 RIG-I-like receptor signaling pathway 12/315 62/7206 1.19003687707e-05 ko04666 Fc gamma R-mediated phagocytosis 17/315 122/7206 1.98504929134e-05 ko04672 Intestinal immune network for IgA production 9/315 37/7206 2.18757065352e-05 ko04612 Antigen processing and presentation 13/315 77/7206 2.43399558189e-05 ko05323 Rheumatoid arthritis 14/315 89/7206 2.72514547689e-05 ko05142 Chagas disease (American trypanosomiasis) 17/315 130/7206 4.58248984943e-05 ko04940 Type I diabetes mellitus 8/315 32/7206 5.11291019475e-05 ko04623 Cytosolic DNA-sensing pathway 9/315 41/7206 5.27821969803e-05 ko05310 Asthma 6/315 17/7206 5.46971551508e-05 ko05161 Hepatitis B 20/315 173/7206 6.04341170035e-05 ko04664 Fc epsilon RI signaling pathway 12/315 77/7206 0.000112285544024 ko04668 TNF signaling pathway 15/315 120/7206 0.000213745888122 ko04670 Leukocyte transendothelial migration 17/315 151/7206 0.000297044460139 ko04640 Hematopoietic cell lineage 10/315 64/7206 0.0004084695805 ko05034 Alcoholism 1/315 238/7206 0.000518530271729 ko05160 Hepatitis C 16/315 153/7206 0.00100616655821 ko05016 Huntington's disease 1/315 215/7206 0.00107994141993 ko05132 Salmonella infection 12/315 98/7206 0.00109114803461 ko04210 Apoptosis 18/315 180/7206 0.00113194437243 ko04514 Cell adhesion molecules (CAMs) 14/315 130/7206 0.00154935605505 ko05143 African trypanosomiasis 6/315 32/7206 0.00229999015281 ko04145 Phagosome 16/315 162/7206 0.0025023811563 ko04611 Platelet activation 16/315 163/7206 0.00259443616971 ko05131 Shigellosis 10/315 82/7206 0.00288020578907 ko04657 IL-17 signaling pathway 10/315 87/7206 0.00444510774645 ko04728 Dopaminergic synapse 1/315 185/7206 0.00513628930086 ko04144 Endocytosis 26/315 342/7206 0.00604959649867 ko05224 Breast cancer 1/315 174/7206 0.00728757940902 ko04723 Retrograde endocannabinoid signaling 1/315 175/7206 0.00737007762386 ko03050 Proteasome 7/315 54/7206 0.00863375743102 ko04137 Mitophagy - animal 9/315 82/7206 0.00919020946916 ko05416 Viral myocarditis 7/315 55/7206 0.00953311221826 ko04550 Signaling pathways regulating pluripotency of stem cells 1/315 165/7206 0.0105788370498 ko05146 Amoebiasis 10/315 99/7206 0.0109354997457 ko05169 Epstein-Barr virus infection 17/315 206/7206 0.0135830122003 ko05134 Legionellosis 8/315 74/7206 0.0149463177259 ko05012 Parkinson's disease 1/315 155/7206 0.0151857841818 ko04390 Hippo signaling pathway 2/315 188/7206 0.0176948559859 ko04110 Cell cycle 1/315 145/7206 0.0217942744554 ko04072 Phospholipase D signaling pathway 15/315 197/7206 0.0323832422277 ko05010 Alzheimer's disease 3/315 202/7206 0.0357768142545 ko05166 HTLV-I infection 20/315 292/7206 0.040392957189 ko00190 Oxidative phosphorylation 1/315 127/7206 0.0452740925313 ko04915 Estrogen signaling pathway 1/315 131/7206 0.0471547940737