ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 43/299 145/7206 6.40043539244e-26 ko04110 Cell cycle 40/299 145/7206 7.81586592847e-23 ko04111 Cell cycle - yeast 30/299 90/7206 5.94810538551e-20 ko03030 DNA replication 19/299 38/7206 5.43564428269e-17 ko03440 Homologous recombination 19/299 41/7206 3.35984047484e-16 ko04113 Meiosis - yeast 21/299 70/7206 2.89804532343e-13 ko00240 Pyrimidine metabolism 23/299 110/7206 7.85135792681e-11 ko03013 RNA transport 28/299 166/7206 1.41668564998e-10 ko03430 Mismatch repair 10/299 22/7206 5.41328846952e-09 ko03460 Fanconi anemia pathway 14/299 51/7206 1.07013365428e-08 ko03008 Ribosome biogenesis in eukaryotes 17/299 79/7206 1.5800018624e-08 ko03410 Base excision repair 12/299 38/7206 2.14815637016e-08 ko03420 Nucleotide excision repair 11/299 46/7206 1.89983195424e-06 ko03022 Basal transcription factors 10/299 44/7206 9.20081744276e-06 ko05166 HTLV-I infection 29/299 292/7206 1.28988222858e-05 ko03018 RNA degradation 13/299 84/7206 3.66235844915e-05 ko04114 Oocyte meiosis 17/299 139/7206 5.63710303838e-05 ko03015 mRNA surveillance pathway 13/299 93/7206 0.000108580603611 ko04151 PI3K-Akt signaling pathway 3/299 390/7206 0.000110969355947 ko00230 Purine metabolism 20/299 194/7206 0.000146384986684 ko04810 Regulation of actin cytoskeleton 1/299 264/7206 0.000233285786134 ko04914 Progesterone-mediated oocyte maturation 13/299 104/7206 0.000339741620434 ko04120 Ubiquitin mediated proteolysis 15/299 138/7206 0.000563998551783 ko03020 RNA polymerase 6/299 29/7206 0.00102702986523 ko04015 Rap1 signaling pathway 2/299 278/7206 0.00105127000925 ko04024 cAMP signaling pathway 2/299 279/7206 0.00105781578603 ko04014 Ras signaling pathway 2/299 279/7206 0.00105781578603 ko04010 MAPK signaling pathway 3/299 321/7206 0.00133858351892 ko05205 Proteoglycans in cancer 2/299 271/7206 0.00154264288956 ko04072 Phospholipase D signaling pathway 1/299 197/7206 0.00337637132028 ko05010 Alzheimer's disease 1/299 202/7206 0.00344556826182 ko04510 Focal adhesion 2/299 240/7206 0.00444800043549 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/299 182/7206 0.00723576928664 ko04152 AMPK signaling pathway 1/299 161/7206 0.0150376613211 ko04071 Sphingolipid signaling pathway 1/299 162/7206 0.0151097574599 ko04611 Platelet activation 1/299 163/7206 0.0152091071297 ko04140 Autophagy - animal 1/299 164/7206 0.0153358065075 ko04062 Chemokine signaling pathway 2/299 201/7206 0.0179738470003 ko04360 Axon guidance 3/299 233/7206 0.0189054345707 ko04142 Lysosome 1/299 151/7206 0.0216907751307 ko05160 Hepatitis C 1/299 153/7206 0.0219080092928 ko05152 Tuberculosis 2/299 187/7206 0.0249184407353 ko04060 Cytokine-cytokine receptor interaction 2/299 191/7206 0.0252591025597 ko04530 Tight junction 3/299 228/7206 0.0264281386632 ko05203 Viral carcinogenesis 19/299 277/7206 0.0298496307919 ko05169 Epstein-Barr virus infection 15/299 206/7206 0.0313792572679 ko04115 p53 signaling pathway 7/299 74/7206 0.0330986196021 ko04630 Jak-STAT signaling pathway 1/299 132/7206 0.0449940548349 ko04380 Osteoclast differentiation 1/299 134/7206 0.0454811513865 ko05231 Choline metabolism in cancer 1/299 134/7206 0.0454811513865 ko04933 AGE-RAGE signaling pathway in diabetic complications 1/299 135/7206 0.0458296872892 ko00670 One carbon pool by folate 3/299 20/7206 0.047801556664