ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 9/233 30/7206 2.61870428154e-07 ko04650 Natural killer cell mediated cytotoxicity 14/233 97/7206 2.3753879026e-06 ko04630 Jak-STAT signaling pathway 16/233 132/7206 4.75707660197e-06 ko05162 Measles 15/233 120/7206 6.47805981564e-06 ko04621 NOD-like receptor signaling pathway 17/233 157/7206 1.11784547343e-05 ko04064 NF-kappa B signaling pathway 13/233 96/7206 1.12540297242e-05 ko05150 Staphylococcus aureus infection 8/233 36/7206 1.46421054083e-05 ko05168 Herpes simplex infection 18/233 182/7206 2.16128854165e-05 ko04622 RIG-I-like receptor signaling pathway 10/233 62/7206 2.52732073555e-05 ko05164 Influenza A 17/233 167/7206 2.53015868713e-05 ko00120 Primary bile acid biosynthesis 6/233 20/7206 2.83807963629e-05 ko04060 Cytokine-cytokine receptor interaction 18/233 191/7206 4.14532369249e-05 ko05145 Toxoplasmosis 14/233 126/7206 5.08455882736e-05 ko04217 Necroptosis 17/233 178/7206 5.74990184431e-05 ko04380 Osteoclast differentiation 14/233 134/7206 0.000100205531868 ko04612 Antigen processing and presentation 10/233 77/7206 0.000168614657862 ko04658 Th1 and Th2 cell differentiation 11/233 96/7206 0.000249126747286 ko05152 Tuberculosis 16/233 187/7206 0.000341917200728 ko05133 Pertussis 10/233 87/7206 0.000463614894384 ko04146 Peroxisome 10/233 89/7206 0.000556936353924 ko04659 Th17 cell differentiation 11/233 106/7206 0.000591307795972 ko05140 Leishmaniasis 9/233 75/7206 0.000647313241161 ko04080 Neuroactive ligand-receptor interaction 3/233 423/7206 0.00090791294893 ko00140 Steroid hormone biosynthesis 6/233 41/7206 0.00186505194319 ko04660 T cell receptor signaling pathway 11/233 124/7206 0.0021613740066 ko05132 Salmonella infection 9/233 98/7206 0.00426874167027 ko04620 Toll-like receptor signaling pathway 9/233 100/7206 0.00488099468175 ko04666 Fc gamma R-mediated phagocytosis 10/233 122/7206 0.00597413718107 ko04672 Intestinal immune network for IgA production 5/233 37/7206 0.00633915823739 ko04062 Chemokine signaling pathway 14/233 201/7206 0.0066969257789 ko05321 Inflammatory bowel disease (IBD) 6/233 56/7206 0.00901278958278 ko04623 Cytosolic DNA-sensing pathway 5/233 41/7206 0.00981901344 ko05161 Hepatitis B 12/233 173/7206 0.0132814398331 ko05320 Autoimmune thyroid disease 4/233 29/7206 0.0134022490244 ko04610 Complement and coagulation cascades 7/233 79/7206 0.0135769517644 ko05332 Graft-versus-host disease 3/233 18/7206 0.0190147091257 ko05034 Alcoholism 2/233 238/7206 0.0250721823626 ko00100 Steroid biosynthesis 3/233 21/7206 0.0288726714368 ko03050 Proteasome 5/233 54/7206 0.0295997978188 ko04310 Wnt signaling pathway 1/233 181/7206 0.0315497467597 ko04728 Dopaminergic synapse 1/233 185/7206 0.0320700796424 ko04390 Hippo signaling pathway 1/233 188/7206 0.0327902020218 ko04360 Axon guidance 2/233 233/7206 0.0357023399336 ko04664 Fc epsilon RI signaling pathway 6/233 77/7206 0.0377643003857 ko05020 Prion diseases 4/233 40/7206 0.0392026703271 ko00980 Metabolism of xenobiotics by cytochrome P450 4/233 40/7206 0.0392026703271 ko00920 Sulfur metabolism 2/233 10/7206 0.0394780901144 ko05330 Allograft rejection 3/233 24/7206 0.0409490358382 ko01212 Fatty acid metabolism 5/233 60/7206 0.0438264512349 ko00051 Fructose and mannose metabolism 4/233 42/7206 0.0456971358054 ko00983 Drug metabolism - other enzymes 4/233 42/7206 0.0456971358054 ko05224 Breast cancer 1/233 174/7206 0.04650623657 ko05131 Shigellosis 6/233 82/7206 0.0489270470572