ko pathway ratio_in_study ratio_in_pop p_value ko05100 Bacterial invasion of epithelial cells 21/293 99/7206 2.78640745835e-10 ko04810 Regulation of actin cytoskeleton 33/293 264/7206 5.68277236696e-09 ko04670 Leukocyte transendothelial migration 24/293 151/7206 7.11700090162e-09 ko04510 Focal adhesion 28/293 240/7206 3.80209280875e-07 ko04666 Fc gamma R-mediated phagocytosis 19/293 122/7206 3.86366074274e-07 ko04530 Tight junction 27/293 228/7206 4.59565932538e-07 ko05131 Shigellosis 15/293 82/7206 8.15143277954e-07 ko05132 Salmonella infection 16/293 98/7206 1.71886589348e-06 ko05130 Pathogenic Escherichia coli infection 14/293 77/7206 2.06023356706e-06 ko04144 Endocytosis 32/293 342/7206 7.94905139679e-06 ko04611 Platelet activation 20/293 163/7206 8.77073706949e-06 ko05205 Proteoglycans in cancer 27/293 271/7206 1.29620686805e-05 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 13/293 79/7206 1.49917895839e-05 ko04514 Cell adhesion molecules (CAMs) 16/293 130/7206 6.7843657556e-05 ko05146 Amoebiasis 13/293 99/7206 0.00016926903159 ko05160 Hepatitis C 16/293 153/7206 0.000458880993974 ko05200 Pathways in cancer 36/293 492/7206 0.000515571354374 ko05418 Fluid shear stress and atherosclerosis 17/293 173/7206 0.000634390816906 ko04668 TNF signaling pathway 13/293 120/7206 0.00111609185034 ko04933 AGE-RAGE signaling pathway in diabetic complications 14/293 135/7206 0.00111962047382 ko04210 Apoptosis 17/293 180/7206 0.00151140985905 ko04390 Hippo signaling pathway 17/293 188/7206 0.00197495387669 ko05410 Hypertrophic cardiomyopathy (HCM) 11/293 100/7206 0.00234441748936 ko04015 Rap1 signaling pathway 22/293 278/7206 0.00271067569235 ko04217 Necroptosis 16/293 178/7206 0.00288937464843 ko00590 Arachidonic acid metabolism 7/293 52/7206 0.00475279400148 ko00363 Bisphenol degradation 2/293 3/7206 0.00481047317729 ko00512 Mucin type O-glycan biosynthesis 5/293 29/7206 0.00571117050607 ko04060 Cytokine-cytokine receptor interaction 16/293 191/7206 0.00770713680575 ko05133 Pertussis 9/293 87/7206 0.00852881183688 ko04520 Adherens junction 10/293 103/7206 0.00883428399193 ko04215 Apoptosis - multiple species 6/293 47/7206 0.0113276977327 ko04722 Neurotrophin signaling pathway 13/293 160/7206 0.0143672679387 ko04512 ECM-receptor interaction 8/293 79/7206 0.0144844054404 ko04912 GnRH signaling pathway 11/293 122/7206 0.0166209535266 ko05034 Alcoholism 3/293 238/7206 0.0189153552101 ko04011 MAPK signaling pathway - yeast 6/293 53/7206 0.0197939625121 ko05012 Parkinson's disease 1/293 155/7206 0.0217965417176 ko05210 Colorectal cancer 8/293 86/7206 0.0231231792005 ko00520 Amino sugar and nucleotide sugar metabolism 6/293 55/7206 0.0233750010696 ko00480 Glutathione metabolism 6/293 55/7206 0.0233750010696 ko04071 Sphingolipid signaling pathway 13/293 162/7206 0.0234036036559 ko04657 IL-17 signaling pathway 8/293 87/7206 0.0246010898196 ko05224 Breast cancer 13/293 174/7206 0.0304047837807 ko05120 Epithelial cell signaling in Helicobacter pylori infection 8/293 92/7206 0.0329895411276 ko05322 Systemic lupus erythematosus 1/293 151/7206 0.0331154240396 ko01524 Platinum drug resistance 7/293 76/7206 0.0341663491257 ko04660 T cell receptor signaling pathway 10/293 124/7206 0.0346894051081 ko04370 VEGF signaling pathway 7/293 77/7206 0.0363307975597 ko00540 Lipopolysaccharide biosynthesis 1/293 1/7206 0.0406605606441 ko05142 Chagas disease (American trypanosomiasis) 10/293 130/7206 0.0428539616192 ko04012 ErbB signaling pathway 9/293 109/7206 0.0433167199446 ko04120 Ubiquitin mediated proteolysis 1/293 138/7206 0.045971121215 ko04114 Oocyte meiosis 1/293 139/7206 0.04639598459 ko04068 FoxO signaling pathway 12/293 167/7206 0.0465321640793 ko05414 Dilated cardiomyopathy 9/293 112/7206 0.047371494668 ko00627 Aminobenzoate degradation 2/293 9/7206 0.0491010050131