ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	150/924	423/7206	2.67114502395e-35
ko04724	Glutamatergic synapse	74/924	152/7206	1.36745252878e-27
ko05033	Nicotine addiction	41/924	56/7206	2.89074867363e-25
ko04721	Synaptic vesicle cycle	46/924	80/7206	1.94361794999e-21
ko05032	Morphine addiction	52/924	110/7206	5.8409235454e-19
ko04727	GABAergic synapse	51/924	110/7206	3.69531498874e-18
ko04728	Dopaminergic synapse	69/924	185/7206	8.72407556438e-18
ko04713	Circadian entrainment	55/924	136/7206	3.3508722635e-16
ko04725	Cholinergic synapse	60/924	160/7206	9.82212236144e-16
ko04723	Retrograde endocannabinoid signaling	62/924	175/7206	7.32130259098e-15
ko04024	cAMP signaling pathway	78/924	279/7206	6.20508792424e-12
ko04726	Serotonergic synapse	46/924	137/7206	1.9751858346e-10
ko04742	Taste transduction	27/924	61/7206	1.18753535105e-09
ko04911	Insulin secretion	39/924	117/7206	6.11695361429e-09
ko04921	Oxytocin signaling pathway	56/924	209/7206	3.88784643151e-08
ko04020	Calcium signaling pathway	66/924	265/7206	5.3119175027e-08
ko04744	Phototransduction	18/924	36/7206	7.02586911951e-08
ko03040	Spliceosome	1/924	145/7206	9.45977909797e-08
ko05031	Amphetamine addiction	31/924	91/7206	1.27316986205e-07
ko04720	Long-term potentiation	32/924	99/7206	3.17092886037e-07
ko04261	Adrenergic signaling in cardiomyocytes	53/924	205/7206	3.46776166509e-07
ko04970	Salivary secretion	31/924	95/7206	3.82122978704e-07
ko05203	Viral carcinogenesis	11/924	277/7206	5.31159468838e-07
ko04360	Axon guidance	56/924	233/7206	1.9527578853e-06
ko04120	Ubiquitin mediated proteolysis	2/924	138/7206	2.02524075968e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/924	74/7206	2.50086718176e-06
ko05168	Herpes simplex infection	5/924	182/7206	2.72621322586e-06
ko04010	MAPK signaling pathway	70/924	321/7206	4.77814221152e-06
ko04060	Cytokine-cytokine receptor interaction	6/924	191/7206	4.8080605651e-06
ko05030	Cocaine addiction	24/924	73/7206	6.7937469385e-06
ko04730	Long-term depression	25/924	78/7206	7.32007527722e-06
ko03013	RNA transport	5/924	166/7206	1.69409192686e-05
ko05164	Influenza A	5/924	167/7206	1.73323346136e-05
ko04514	Cell adhesion molecules (CAMs)	34/924	130/7206	3.00788021191e-05
ko04966	Collecting duct acid secretion	12/924	26/7206	3.16590295687e-05
ko04141	Protein processing in endoplasmic reticulum	7/924	184/7206	4.49839793425e-05
ko04621	NOD-like receptor signaling pathway	5/924	157/7206	5.04221631615e-05
ko05322	Systemic lupus erythematosus	5/924	151/7206	0.000103923699913
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/924	14/7206	0.000104309398602
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/924	79/7206	0.000110870236391
ko04014	Ras signaling pathway	58/924	279/7206	0.000157971845473
ko05205	Proteoglycans in cancer	16/924	271/7206	0.000197024860499
ko04540	Gap junction	31/924	128/7206	0.000411355231093
ko05169	Epstein-Barr virus infection	11/924	206/7206	0.000449956492171
ko04924	Renin secretion	23/924	86/7206	0.000466804931739
ko04612	Antigen processing and presentation	1/924	77/7206	0.000479404742256
ko03008	Ribosome biogenesis in eukaryotes	1/924	79/7206	0.000500086089042
ko04971	Gastric acid secretion	25/924	98/7206	0.0006193695318
ko04072	Phospholipase D signaling pathway	42/924	197/7206	0.000725249755253
ko04972	Pancreatic secretion	27/924	111/7206	0.000817182892901
ko04022	cGMP-PKG signaling pathway	45/924	216/7206	0.000849370805075
ko04070	Phosphatidylinositol signaling system	27/924	112/7206	0.000897203067046
ko04740	Olfactory transduction	21/924	80/7206	0.00106488260209
ko04260	Cardiac muscle contraction	24/924	98/7206	0.00126935943416
ko04925	Aldosterone synthesis and secretion	25/924	105/7206	0.00173816881362
ko04064	NF-kappa B signaling pathway	3/924	96/7206	0.00183427139503
ko00240	Pyrimidine metabolism	4/924	110/7206	0.00215607222906
ko05162	Measles	5/924	120/7206	0.00219724940829
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/924	59/7206	0.00268720088724
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/924	182/7206	0.00341856722334
ko05145	Toxoplasmosis	6/924	126/7206	0.00431407414966
ko05140	Leishmaniasis	2/924	75/7206	0.00468733627473
ko04915	Estrogen signaling pathway	28/924	131/7206	0.00530647771896
ko04110	Cell cycle	8/924	145/7206	0.00544605465764
ko05414	Dilated cardiomyopathy	25/924	112/7206	0.00609457636717
ko05110	Vibrio cholerae infection	16/924	63/7206	0.00662964526603
ko03018	RNA degradation	3/924	84/7206	0.00767948618322
ko00480	Glutathione metabolism	1/924	55/7206	0.00773476257832
ko05161	Hepatitis B	11/924	173/7206	0.00779079774258
ko04964	Proximal tubule bicarbonate reclamation	9/924	29/7206	0.00825160132462
ko01200	Carbon metabolism	7/924	128/7206	0.0105033575326
ko04391	Hippo signaling pathway - fly	20/924	90/7206	0.010875221075
ko00590	Arachidonic acid metabolism	1/924	52/7206	0.0114524883847
ko04217	Necroptosis	12/924	178/7206	0.0120765251068
ko04640	Hematopoietic cell lineage	2/924	64/7206	0.0138396939819
ko01524	Platinum drug resistance	3/924	76/7206	0.0150045588892
ko05166	HTLV-I infection	24/924	292/7206	0.0155174918656
ko04146	Peroxisome	4/924	89/7206	0.0155312371905
ko04668	TNF signaling pathway	7/924	120/7206	0.0185102413961
ko00330	Arginine and proline metabolism	2/924	61/7206	0.019886415165
ko04214	Apoptosis - fly	3/924	72/7206	0.0210772150737
ko00310	Lysine degradation	3/924	73/7206	0.0211114256452
ko04745	Phototransduction - fly	10/924	38/7206	0.0239255115238
ko04144	Endocytosis	58/924	342/7206	0.0248462707409
ko05144	Malaria	1/924	45/7206	0.0249309632543
ko00071	Fatty acid degradation	1/924	45/7206	0.0249309632543
ko00620	Pyruvate metabolism	1/924	46/7206	0.0250349092703
ko03420	Nucleotide excision repair	1/924	46/7206	0.0250349092703
ko04015	Rap1 signaling pathway	48/924	278/7206	0.0278945795007
ko04976	Bile secretion	17/924	80/7206	0.0288227800291
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/924	15/7206	0.0341310385546
ko04350	TGF-beta signaling pathway	6/924	103/7206	0.0359940110599
ko05222	Small cell lung cancer	5/924	89/7206	0.0377689290966
ko03022	Basal transcription factors	1/924	44/7206	0.0378924004737
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/924	92/7206	0.0392091437675
ko04371	Apelin signaling pathway	32/924	177/7206	0.0400258850726
ko05321	Inflammatory bowel disease (IBD)	2/924	56/7206	0.0416270838
ko05146	Amoebiasis	6/924	99/7206	0.0473994342646
ko05034	Alcoholism	41/924	238/7206	0.047881954611
ko05410	Hypertrophic cardiomyopathy (HCM)	20/924	100/7206	0.0481835810703
ko05231	Choline metabolism in cancer	25/924	134/7206	0.0495323356594