ko pathway ratio_in_study ratio_in_pop p_value ko04744 Phototransduction 16/198 36/7206 2.59822544923e-16 ko04727 GABAergic synapse 20/198 110/7206 1.16505840093e-11 ko04724 Glutamatergic synapse 23/198 152/7206 1.62810513652e-11 ko04713 Circadian entrainment 20/198 136/7206 6.28898122593e-10 ko05033 Nicotine addiction 13/198 56/7206 2.2991877976e-09 ko05030 Cocaine addiction 14/198 73/7206 7.85499874022e-09 ko04024 cAMP signaling pathway 27/198 279/7206 8.33486376127e-09 ko04740 Olfactory transduction 14/198 80/7206 2.70512669898e-08 ko05032 Morphine addiction 16/198 110/7206 4.15142047945e-08 ko04728 Dopaminergic synapse 20/198 185/7206 1.36063464262e-07 ko04721 Synaptic vesicle cycle 13/198 80/7206 2.14682124117e-07 ko04911 Insulin secretion 15/198 117/7206 6.06880784017e-07 ko05031 Amphetamine addiction 13/198 91/7206 1.00140719141e-06 ko04723 Retrograde endocannabinoid signaling 18/198 175/7206 1.24725941819e-06 ko05014 Amyotrophic lateral sclerosis (ALS) 11/198 74/7206 4.69628084563e-06 ko04725 Cholinergic synapse 15/198 160/7206 3.04288616949e-05 ko04080 Neuroactive ligand-receptor interaction 27/198 423/7206 3.68317975721e-05 ko04720 Long-term potentiation 11/198 99/7206 7.77522385057e-05 ko05034 Alcoholism 18/198 238/7206 8.78939958664e-05 ko04261 Adrenergic signaling in cardiomyocytes 16/198 205/7206 0.000152201525984 ko04726 Serotonergic synapse 12/198 137/7206 0.000363899039778 ko04745 Phototransduction - fly 5/198 38/7206 0.00357493694735 ko04978 Mineral absorption 5/198 40/7206 0.00448352018991 ko05166 HTLV-I infection 1/198 292/7206 0.00506903078714 ko04966 Collecting duct acid secretion 4/198 26/7206 0.00514454955744 ko04971 Gastric acid secretion 8/198 98/7206 0.00536135147871 ko05110 Vibrio cholerae infection 6/198 63/7206 0.0073787784803 ko04964 Proximal tubule bicarbonate reclamation 4/198 29/7206 0.00766602029352 ko04626 Plant-pathogen interaction 3/198 18/7206 0.0122963351518 ko04062 Chemokine signaling pathway 12/198 201/7206 0.012626225447 ko04970 Salivary secretion 7/198 95/7206 0.0153252739378 ko04976 Bile secretion 6/198 80/7206 0.0222852901984 ko04961 Endocrine and other factor-regulated calcium reabsorption 5/198 59/7206 0.0224697591963 ko04014 Ras signaling pathway 14/198 279/7206 0.0245284113638 ko04960 Aldosterone-regulated sodium reabsorption 4/198 41/7206 0.0253456635577 ko04973 Carbohydrate digestion and absorption 4/198 42/7206 0.0274298825947 ko00830 Retinol metabolism 4/198 42/7206 0.0274298825947 ko04972 Pancreatic secretion 7/198 111/7206 0.0327620992723 ko05203 Viral carcinogenesis 2/198 277/7206 0.0361070006998 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/198 92/7206 0.0404925725627 ko00230 Purine metabolism 10/198 194/7206 0.0450270674355