ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 21/309 79/7206 7.52425505751e-12 ko04974 Protein digestion and absorption 22/309 96/7206 5.79139600961e-11 ko04510 Focal adhesion 34/309 240/7206 4.6998621261e-10 ko05205 Proteoglycans in cancer 34/309 271/7206 1.17846231222e-08 ko05217 Basal cell carcinoma 16/309 68/7206 1.72314676545e-08 ko04390 Hippo signaling pathway 27/309 188/7206 2.40474032779e-08 ko04916 Melanogenesis 23/309 142/7206 2.80227452855e-08 ko05146 Amoebiasis 19/309 99/7206 2.81221500943e-08 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 16/309 79/7206 1.64578257478e-07 ko05200 Pathways in cancer 46/309 492/7206 3.62647858633e-07 ko04550 Signaling pathways regulating pluripotency of stem cells 23/309 165/7206 4.74027691172e-07 ko05224 Breast cancer 22/309 174/7206 4.46991653363e-06 ko04310 Wnt signaling pathway 22/309 181/7206 8.55811819176e-06 ko04151 PI3K-Akt signaling pathway 35/309 390/7206 2.66716329724e-05 ko04810 Regulation of actin cytoskeleton 27/309 264/7206 2.86964048001e-05 ko04670 Leukocyte transendothelial migration 18/309 151/7206 7.40247305758e-05 ko05410 Hypertrophic cardiomyopathy (HCM) 13/309 100/7206 0.000316104372144 ko04514 Cell adhesion molecules (CAMs) 15/309 130/7206 0.000419863414022 ko04666 Fc gamma R-mediated phagocytosis 14/309 122/7206 0.000686963605362 ko05414 Dilated cardiomyopathy 13/309 112/7206 0.000951945301732 ko00512 Mucin type O-glycan biosynthesis 6/309 29/7206 0.00121872931396 ko04933 AGE-RAGE signaling pathway in diabetic complications 14/309 135/7206 0.00185609257386 ko04530 Tight junction 20/309 228/7206 0.00223409147518 ko05034 Alcoholism 2/309 238/7206 0.00307075772517 ko05100 Bacterial invasion of epithelial cells 11/309 99/7206 0.00326959978902 ko00363 Bisphenol degradation 2/309 3/7206 0.00534300007435 ko04060 Cytokine-cytokine receptor interaction 17/309 191/7206 0.00535084971284 ko04640 Hematopoietic cell lineage 8/309 64/7206 0.00569930864627 ko04015 Rap1 signaling pathway 22/309 278/7206 0.00572376518907 ko00590 Arachidonic acid metabolism 7/309 52/7206 0.00633756298912 ko04150 mTOR signaling pathway 16/309 184/7206 0.00812290966569 ko00480 Glutathione metabolism 7/309 55/7206 0.00861945953781 ko04080 Neuroactive ligand-receptor interaction 8/309 423/7206 0.00895739767287 ko04140 Autophagy - animal 1/309 164/7206 0.0103318164472 ko00643 Styrene degradation 2/309 4/7206 0.0103834878705 ko05166 HTLV-I infection 22/309 292/7206 0.0109992533462 ko05418 Fluid shear stress and atherosclerosis 15/309 173/7206 0.0113527373314 ko00350 Tyrosine metabolism 5/309 33/7206 0.0124057570451 ko05222 Small cell lung cancer 9/309 89/7206 0.013631028404 ko05012 Parkinson's disease 1/309 155/7206 0.0149638736017 ko05204 Chemical carcinogenesis 6/309 48/7206 0.0159384202221 ko00982 Drug metabolism - cytochrome P450 5/309 37/7206 0.0198327609738 ko05206 MicroRNAs in cancer 14/309 177/7206 0.0230840268649 ko05131 Shigellosis 8/309 82/7206 0.0237119015011 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/309 182/7206 0.0249161847489 ko00980 Metabolism of xenobiotics by cytochrome P450 5/309 40/7206 0.0269919330258 ko04144 Endocytosis 23/309 342/7206 0.0282087473511 ko04611 Platelet activation 13/309 163/7206 0.0287003741605 ko04120 Ubiquitin mediated proteolysis 1/309 138/7206 0.0313651381119 ko04114 Oocyte meiosis 1/309 139/7206 0.0315673777888 ko05132 Salmonella infection 9/309 98/7206 0.0374360032594 ko05160 Hepatitis C 12/309 153/7206 0.0402114002086 ko04912 GnRH signaling pathway 10/309 122/7206 0.0407212444002 ko04350 TGF-beta signaling pathway 9/309 103/7206 0.0427085316204 ko00540 Lipopolysaccharide biosynthesis 1/309 1/7206 0.0428809325564 ko01200 Carbon metabolism 1/309 128/7206 0.0449563073889 ko04152 AMPK signaling pathway 2/309 161/7206 0.0487032619419