ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	176/990	423/7206	9.72075902638e-49
ko05033	Nicotine addiction	46/990	56/7206	7.90617308588e-31
ko04724	Glutamatergic synapse	78/990	152/7206	5.92440843966e-29
ko05032	Morphine addiction	62/990	110/7206	3.71635735996e-26
ko04727	GABAergic synapse	60/990	110/7206	2.55141341227e-24
ko04713	Circadian entrainment	62/990	136/7206	8.97354956752e-20
ko04728	Dopaminergic synapse	73/990	185/7206	1.1949521591e-18
ko04723	Retrograde endocannabinoid signaling	69/990	175/7206	1.16079532693e-17
ko04721	Synaptic vesicle cycle	43/990	80/7206	1.9659824849e-17
ko04725	Cholinergic synapse	63/990	160/7206	3.46591992108e-16
ko04024	cAMP signaling pathway	89/990	279/7206	1.9824963966e-15
ko04744	Phototransduction	25/990	36/7206	2.83148249622e-14
ko04726	Serotonergic synapse	53/990	137/7206	1.94870390154e-13
ko04742	Taste transduction	32/990	61/7206	6.55682956673e-13
ko04911	Insulin secretion	45/990	117/7206	1.69507146828e-11
ko04020	Calcium signaling pathway	77/990	265/7206	3.26389819556e-11
ko04921	Oxytocin signaling pathway	60/990	209/7206	8.89293898084e-09
ko03040	Spliceosome	1/990	145/7206	1.45351398233e-08
ko04970	Salivary secretion	34/990	95/7206	4.37398602717e-08
ko05203	Viral carcinogenesis	11/990	277/7206	6.03008949493e-08
ko04261	Adrenergic signaling in cardiomyocytes	57/990	205/7206	7.87108272186e-08
ko05030	Cocaine addiction	28/990	73/7206	1.26649590773e-07
ko05031	Amphetamine addiction	32/990	91/7206	1.74898249994e-07
ko05164	Influenza A	4/990	167/7206	5.95765941441e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	27/990	74/7206	6.90284728225e-07
ko04060	Cytokine-cytokine receptor interaction	6/990	191/7206	1.02808778207e-06
ko04720	Long-term potentiation	31/990	99/7206	5.07947484249e-06
ko05322	Systemic lupus erythematosus	4/990	151/7206	6.12511281195e-06
ko04360	Axon guidance	56/990	233/7206	1.66766278508e-05
ko04514	Cell adhesion molecules (CAMs)	36/990	130/7206	2.53245453161e-05
ko04120	Ubiquitin mediated proteolysis	4/990	138/7206	2.64148436749e-05
ko05169	Epstein-Barr virus infection	10/990	206/7206	4.96049872592e-05
ko04972	Pancreatic secretion	31/990	111/7206	7.03921052598e-05
ko03013	RNA transport	7/990	166/7206	8.29649333951e-05
ko04010	MAPK signaling pathway	69/990	321/7206	8.99395512484e-05
ko04971	Gastric acid secretion	28/990	98/7206	9.31929953086e-05
ko04141	Protein processing in endoplasmic reticulum	9/990	184/7206	0.000124283394948
ko05168	Herpes simplex infection	9/990	182/7206	0.00017414969234
ko04621	NOD-like receptor signaling pathway	7/990	157/7206	0.000228563787374
ko05162	Measles	4/990	120/7206	0.00023812642816
ko04022	cGMP-PKG signaling pathway	49/990	216/7206	0.000272126840175
ko04260	Cardiac muscle contraction	27/990	98/7206	0.000286418324296
ko05205	Proteoglycans in cancer	18/990	271/7206	0.000287529511746
ko04966	Collecting duct acid secretion	11/990	26/7206	0.00033325919775
ko04730	Long-term depression	23/990	78/7206	0.000340285836295
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/990	79/7206	0.000373898363335
ko04740	Olfactory transduction	23/990	80/7206	0.000419400155536
ko04072	Phospholipase D signaling pathway	45/990	197/7206	0.000467645898512
ko05110	Vibrio cholerae infection	19/990	63/7206	0.000633251546209
ko05161	Hepatitis B	10/990	173/7206	0.00108474271415
ko04070	Phosphatidylinositol signaling system	28/990	112/7206	0.00125552759145
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/990	14/7206	0.00128519074709
ko03008	Ribosome biogenesis in eukaryotes	2/990	79/7206	0.00144774865185
ko05140	Leishmaniasis	2/990	75/7206	0.00208200603536
ko04612	Antigen processing and presentation	2/990	77/7206	0.00219428009507
ko04925	Aldosterone synthesis and secretion	26/990	105/7206	0.00233246162028
ko04540	Gap junction	30/990	128/7206	0.00262621929248
ko04976	Bile secretion	21/990	80/7206	0.00274149555556
ko05414	Dilated cardiomyopathy	27/990	112/7206	0.00321102971757
ko04014	Ras signaling pathway	56/990	279/7206	0.00325262037159
ko03018	RNA degradation	3/990	84/7206	0.00359981802041
ko04924	Renin secretion	22/990	86/7206	0.00385917926236
ko00480	Glutathione metabolism	1/990	55/7206	0.00503547418415
ko04350	TGF-beta signaling pathway	5/990	103/7206	0.00564846690396
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/990	182/7206	0.00629876825361
ko00590	Arachidonic acid metabolism	1/990	52/7206	0.00748379478489
ko00240	Pyrimidine metabolism	6/990	110/7206	0.00764017751694
ko00290	Valine, leucine and isoleucine biosynthesis	3/990	4/7206	0.00928218920288
ko04640	Hematopoietic cell lineage	2/990	64/7206	0.00942922448883
ko04064	NF-kappa B signaling pathway	5/990	96/7206	0.0106794463209
ko05133	Pertussis	4/990	87/7206	0.011035874429
ko05219	Bladder cancer	1/990	48/7206	0.0110570056218
ko04510	Focal adhesion	20/990	240/7206	0.0127713915436
ko04964	Proximal tubule bicarbonate reclamation	9/990	29/7206	0.0128458951239
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/990	59/7206	0.013342349454
ko04110	Cell cycle	10/990	145/7206	0.0141704791756
ko04915	Estrogen signaling pathway	28/990	131/7206	0.0144828106517
ko04214	Apoptosis - fly	3/990	72/7206	0.0147046550051
ko05166	HTLV-I infection	26/990	292/7206	0.0147338159371
ko04140	Autophagy - animal	12/990	164/7206	0.0153096281452
ko05144	Malaria	1/990	45/7206	0.0163821227762
ko00071	Fatty acid degradation	1/990	45/7206	0.0163821227762
ko03420	Nucleotide excision repair	1/990	46/7206	0.0164547576524
ko05215	Prostate cancer	7/990	111/7206	0.0179037556637
ko05321	Inflammatory bowel disease (IBD)	2/990	56/7206	0.0193017254314
ko04218	Cellular senescence	14/990	177/7206	0.0200261071495
ko04630	Jak-STAT signaling pathway	9/990	132/7206	0.0206221033082
ko04711	Circadian rhythm - fly	5/990	13/7206	0.0240363048508
ko03022	Basal transcription factors	1/990	44/7206	0.024976035189
ko05418	Fluid shear stress and atherosclerosis	14/990	173/7206	0.025462390189
ko04657	IL-17 signaling pathway	5/990	87/7206	0.0272901237003
ko00280	Valine, leucine and isoleucine degradation	2/990	54/7206	0.0276918046045
ko04745	Phototransduction - fly	10/990	38/7206	0.0323943184515
ko05016	Huntington's disease	19/990	215/7206	0.0342472264817
ko04658	Th1 and Th2 cell differentiation	6/990	96/7206	0.035020462534
ko04217	Necroptosis	15/990	178/7206	0.0359438970986
ko00310	Lysine degradation	4/990	73/7206	0.0390422912476
ko04115	p53 signaling pathway	4/990	74/7206	0.039594032621
ko00330	Arginine and proline metabolism	3/990	61/7206	0.040087277102
ko04622	RIG-I-like receptor signaling pathway	3/990	62/7206	0.0401780691744
ko05231	Choline metabolism in cancer	27/990	134/7206	0.0413663099129
ko04923	Regulation of lipolysis in adipocytes	17/990	77/7206	0.04383167254
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/990	15/7206	0.0444062339998
ko04668	TNF signaling pathway	9/990	120/7206	0.0445428204273
ko05206	MicroRNAs in cancer	15/990	177/7206	0.0456063535464