ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 17/78 191/7206 1.17549242388e-11 ko05340 Primary immunodeficiency 9/78 30/7206 1.51395668275e-11 ko05168 Herpes simplex infection 15/78 182/7206 6.63403107385e-10 ko05152 Tuberculosis 15/78 187/7206 9.70959705495e-10 ko05162 Measles 12/78 120/7206 4.48966167175e-09 ko04612 Antigen processing and presentation 10/78 77/7206 7.48240327565e-09 ko04621 NOD-like receptor signaling pathway 13/78 157/7206 9.83739044488e-09 ko04064 NF-kappa B signaling pathway 10/78 96/7206 6.52640949685e-08 ko05145 Toxoplasmosis 11/78 126/7206 8.68661226781e-08 ko05321 Inflammatory bowel disease (IBD) 8/78 56/7206 1.22219054478e-07 ko04630 Jak-STAT signaling pathway 11/78 132/7206 1.40507180383e-07 ko05164 Influenza A 12/78 167/7206 1.86428579149e-07 ko04217 Necroptosis 12/78 178/7206 3.74070430379e-07 ko04620 Toll-like receptor signaling pathway 9/78 100/7206 1.09616746295e-06 ko05140 Leishmaniasis 8/78 75/7206 1.23072203074e-06 ko05330 Allograft rejection 5/78 24/7206 4.72421032565e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/78 191/7206 5.61825280947e-06 ko05144 Malaria 6/78 45/7206 7.70939207708e-06 ko04650 Natural killer cell mediated cytotoxicity 8/78 97/7206 8.70849983126e-06 ko05320 Autoimmune thyroid disease 5/78 29/7206 1.26525932224e-05 ko04210 Apoptosis 10/78 180/7206 2.1288210634e-05 ko05160 Hepatitis C 9/78 153/7206 3.62066319429e-05 ko04668 TNF signaling pathway 8/78 120/7206 4.1462908111e-05 ko04660 T cell receptor signaling pathway 8/78 124/7206 5.2469111004e-05 ko04145 Phagosome 9/78 162/7206 5.67655255016e-05 ko05142 Chagas disease (American trypanosomiasis) 8/78 130/7206 7.34780242187e-05 ko04380 Osteoclast differentiation 8/78 134/7206 9.10467479655e-05 ko05161 Hepatitis B 9/78 173/7206 9.45473353814e-05 ko04659 Th17 cell differentiation 7/78 106/7206 0.00013690078296 ko05133 Pertussis 6/78 87/7206 0.000333460938153 ko05169 Epstein-Barr virus infection 9/78 206/7206 0.000353380150981 ko05323 Rheumatoid arthritis 6/78 89/7206 0.000377219666957 ko04514 Cell adhesion molecules (CAMs) 7/78 130/7206 0.0004823242133 ko04672 Intestinal immune network for IgA production 4/78 37/7206 0.000639800572323 ko05146 Amoebiasis 6/78 99/7206 0.000667768071752 ko05310 Asthma 3/78 17/7206 0.000743821227648 ko05332 Graft-versus-host disease 3/78 18/7206 0.000885656198253 ko05166 HTLV-I infection 10/78 292/7206 0.00111843519022 ko05134 Legionellosis 5/78 74/7206 0.00117448396673 ko05416 Viral myocarditis 4/78 55/7206 0.00285212505824 ko04658 Th1 and Th2 cell differentiation 5/78 96/7206 0.00370587065052 ko04622 RIG-I-like receptor signaling pathway 4/78 62/7206 0.00440663834149 ko04940 Type I diabetes mellitus 3/78 32/7206 0.00482867519532 ko04062 Chemokine signaling pathway 7/78 201/7206 0.005861363969 ko01524 Platinum drug resistance 4/78 76/7206 0.00904605353974 ko04664 Fc epsilon RI signaling pathway 4/78 77/7206 0.00946475806795 ko05203 Viral carcinogenesis 8/78 277/7206 0.00981942692908 ko04666 Fc gamma R-mediated phagocytosis 5/78 122/7206 0.0101156204657 ko04932 Non-alcoholic fatty liver disease (NAFLD) 6/78 182/7206 0.0136610794596 ko04917 Prolactin signaling pathway 4/78 87/7206 0.0143585663224 ko04933 AGE-RAGE signaling pathway in diabetic complications 5/78 135/7206 0.015185270602 ko05132 Salmonella infection 4/78 98/7206 0.0213247273873 ko04670 Leukocyte transendothelial migration 5/78 151/7206 0.0234698965846 ko04071 Sphingolipid signaling pathway 5/78 162/7206 0.0305987322863 ko04066 HIF-1 signaling pathway 4/78 123/7206 0.0438651706367 ko05143 African trypanosomiasis 2/78 32/7206 0.0465423059572