ko pathway ratio_in_study ratio_in_pop p_value ko04360 Axon guidance 24/211 233/7206 6.26521225387e-08 ko04930 Type II diabetes mellitus 9/211 54/7206 2.2583272133e-05 ko04010 MAPK signaling pathway 23/211 321/7206 5.85227790019e-05 ko05206 MicroRNAs in cancer 15/211 177/7206 0.000199448519958 ko05033 Nicotine addiction 8/211 56/7206 0.000200467939846 ko04728 Dopaminergic synapse 15/211 185/7206 0.000323404915928 ko04144 Endocytosis 22/211 342/7206 0.000430720392923 ko00515 Mannose type O-glycan biosynthesis 5/211 25/7206 0.000675761847116 ko04520 Adherens junction 10/211 103/7206 0.000820919363657 ko04550 Signaling pathways regulating pluripotency of stem cells 13/211 165/7206 0.00105669897591 ko04068 FoxO signaling pathway 13/211 167/7206 0.00118099974552 ko04724 Glutamatergic synapse 12/211 152/7206 0.0016097532072 ko04723 Retrograde endocannabinoid signaling 13/211 175/7206 0.0018070783704 ko04931 Insulin resistance 11/211 137/7206 0.00218800583885 ko05210 Colorectal cancer 8/211 86/7206 0.00353845663298 ko04391 Hippo signaling pathway - fly 8/211 90/7206 0.00468022027434 ko04727 GABAergic synapse 9/211 110/7206 0.00479844874532 ko05032 Morphine addiction 9/211 110/7206 0.00479844874532 ko04664 Fc epsilon RI signaling pathway 7/211 77/7206 0.00708424433187 ko04071 Sphingolipid signaling pathway 11/211 162/7206 0.00782317436313 ko04668 TNF signaling pathway 9/211 120/7206 0.00841427084549 ko04014 Ras signaling pathway 16/211 279/7206 0.00968290252155 ko04211 Longevity regulating pathway 9/211 123/7206 0.00982511493231 ko04914 Progesterone-mediated oocyte maturation 8/211 104/7206 0.0109950764569 ko04213 Longevity regulating pathway - multiple species 7/211 86/7206 0.0127050773856 ko04624 Toll and Imd signaling pathway 5/211 49/7206 0.0137545139247 ko04713 Circadian entrainment 9/211 136/7206 0.0180787721894 ko00310 Lysine degradation 6/211 73/7206 0.0196123389036 ko05211 Renal cell carcinoma 7/211 96/7206 0.0221007797774 ko04024 cAMP signaling pathway 15/211 279/7206 0.0268084064755 ko04152 AMPK signaling pathway 10/211 161/7206 0.0274538552969 ko04350 TGF-beta signaling pathway 7/211 103/7206 0.0310126543036 ko05212 Pancreatic cancer 6/211 83/7206 0.0342755676012 ko05213 Endometrial cancer 5/211 62/7206 0.0344789378908 ko04330 Notch signaling pathway 5/211 62/7206 0.0344789378908 ko04910 Insulin signaling pathway 10/211 172/7206 0.0349509970284 ko01521 EGFR tyrosine kinase inhibitor resistance 7/211 106/7206 0.0354800458945 ko05161 Hepatitis B 10/211 173/7206 0.0358125088333 ko04917 Prolactin signaling pathway 6/211 87/7206 0.0417111849854 ko04212 Longevity regulating pathway - worm 6/211 87/7206 0.0417111849854 ko04015 Rap1 signaling pathway 14/211 278/7206 0.0436752936374 ko05215 Prostate cancer 7/211 111/7206 0.0438371001287 ko04920 Adipocytokine signaling pathway 6/211 89/7206 0.0457826033843