ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 11/91 134/7206 8.12571460905e-07 ko04933 AGE-RAGE signaling pathway in diabetic complications 10/91 135/7206 6.74920827078e-06 ko04974 Protein digestion and absorption 8/91 96/7206 2.53528705343e-05 ko04931 Insulin resistance 9/91 137/7206 5.21929741308e-05 ko04512 ECM-receptor interaction 7/91 79/7206 5.62192090139e-05 ko05321 Inflammatory bowel disease (IBD) 6/91 56/7206 6.71532259821e-05 ko04668 TNF signaling pathway 8/91 120/7206 0.000125520713907 ko04658 Th1 and Th2 cell differentiation 7/91 96/7206 0.000194310196025 ko04920 Adipocytokine signaling pathway 6/91 89/7206 0.00086130895947 ko05166 HTLV-I infection 11/91 292/7206 0.00105286733428 ko05142 Chagas disease (American trypanosomiasis) 7/91 130/7206 0.00121766003175 ko04932 Non-alcoholic fatty liver disease (NAFLD) 8/91 182/7206 0.00201951324057 ko04510 Focal adhesion 9/91 240/7206 0.00315221289224 ko04930 Type II diabetes mellitus 4/91 54/7206 0.00465054176413 ko04657 IL-17 signaling pathway 5/91 87/7206 0.00470930603478 ko04662 B cell receptor signaling pathway 5/91 88/7206 0.0049441210394 ko05164 Influenza A 7/91 167/7206 0.0050082263035 ko04068 FoxO signaling pathway 7/91 167/7206 0.0050082263035 ko05323 Rheumatoid arthritis 5/91 89/7206 0.00518714556797 ko05161 Hepatitis B 7/91 173/7206 0.00606065959761 ko04218 Cellular senescence 7/91 177/7206 0.00684907438791 ko04064 NF-kappa B signaling pathway 5/91 96/7206 0.00713085867605 ko04210 Apoptosis 7/91 180/7206 0.00748880264798 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 2/91 11/7206 0.00805591244211 ko05146 Amoebiasis 5/91 99/7206 0.00810196071803 ko04620 Toll-like receptor signaling pathway 5/91 100/7206 0.00844513553118 ko04659 Th17 cell differentiation 5/91 106/7206 0.0107184352141 ko05160 Hepatitis C 6/91 153/7206 0.0125886998622 ko00401 Novobiocin biosynthesis 1/91 1/7206 0.0126283652512 ko05134 Legionellosis 4/91 74/7206 0.0139858732745 ko04115 p53 signaling pathway 4/91 74/7206 0.0139858732745 ko04621 NOD-like receptor signaling pathway 6/91 157/7206 0.0141588199231 ko05144 Malaria 3/91 45/7206 0.0188656757215 ko00360 Phenylalanine metabolism 2/91 17/7206 0.0189660113679 ko04660 T cell receptor signaling pathway 5/91 124/7206 0.0199731602282 ko04910 Insulin signaling pathway 6/91 172/7206 0.021266227184 ko05210 Colorectal cancer 4/91 86/7206 0.0230402329089 ko04917 Prolactin signaling pathway 4/91 87/7206 0.0239236510714 ko00254 Aflatoxin biosynthesis 1/91 2/7206 0.0250989854821 ko04630 Jak-STAT signaling pathway 5/91 132/7206 0.0253838843492 ko05222 Small cell lung cancer 4/91 89/7206 0.0257516872812 ko05120 Epithelial cell signaling in Helicobacter pylori infection 4/91 92/7206 0.0286480457137 ko04151 PI3K-Akt signaling pathway 10/91 390/7206 0.0307343456798 ko05211 Renal cell carcinoma 4/91 96/7206 0.0328009219539 ko04060 Cytokine-cytokine receptor interaction 6/91 191/7206 0.0333236226797 ko05167 Kaposi's sarcoma-associated herpesvirus infection 6/91 191/7206 0.0333236226797 ko04350 TGF-beta signaling pathway 4/91 103/7206 0.0408776966118 ko04270 Vascular smooth muscle contraction 5/91 154/7206 0.0448207135681 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 1/91 4/7206 0.0495747623568