ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 17/268 79/7206 3.01966644803e-09 ko04510 Focal adhesion 27/268 240/7206 2.14764010677e-07 ko04974 Protein digestion and absorption 16/268 96/7206 3.90476148443e-07 ko04380 Osteoclast differentiation 17/268 134/7206 8.42600287737e-06 ko05410 Hypertrophic cardiomyopathy (HCM) 14/268 100/7206 1.7272895198e-05 ko00020 Citrate cycle (TCA cycle) 8/268 35/7206 3.23625057886e-05 ko05414 Dilated cardiomyopathy 14/268 112/7206 6.29502640782e-05 ko04621 NOD-like receptor signaling pathway 16/268 157/7206 0.000226013950142 ko04060 Cytokine-cytokine receptor interaction 18/268 191/7206 0.000249192263439 ko00620 Pyruvate metabolism 8/268 46/7206 0.000251545423788 ko01200 Carbon metabolism 14/268 128/7206 0.000267488172643 ko05164 Influenza A 16/268 167/7206 0.00045648510888 ko04668 TNF signaling pathway 13/268 120/7206 0.000484666826148 ko05144 Malaria 7/268 45/7206 0.00122819006142 ko04933 AGE-RAGE signaling pathway in diabetic complications 13/268 135/7206 0.00147399234654 ko00010 Glycolysis / Gluconeogenesis 9/268 74/7206 0.00158098388611 ko04672 Intestinal immune network for IgA production 6/268 37/7206 0.00220143915287 ko05146 Amoebiasis 10/268 99/7206 0.00360306864278 ko04270 Vascular smooth muscle contraction 13/268 154/7206 0.00744374512869 ko00643 Styrene degradation 2/268 4/7206 0.00786780896035 ko00760 Nicotinate and nicotinamide metabolism 5/268 34/7206 0.00787592181841 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8/268 79/7206 0.00875395975349 ko05131 Shigellosis 8/268 82/7206 0.010874330063 ko05161 Hepatitis B 13/268 173/7206 0.0134436382098 ko04015 Rap1 signaling pathway 3/268 278/7206 0.0139532350018 ko04141 Protein processing in endoplasmic reticulum 1/268 184/7206 0.0155682545174 ko04728 Dopaminergic synapse 1/268 185/7206 0.0157281038876 ko05321 Inflammatory bowel disease (IBD) 6/268 56/7206 0.0171063846449 ko05323 Rheumatoid arthritis 8/268 89/7206 0.0172700116027 ko00362 Benzoate degradation 2/268 6/7206 0.0187203120122 ko00565 Ether lipid metabolism 5/268 42/7206 0.0189387809153 ko05168 Herpes simplex infection 13/268 182/7206 0.025475431913 ko04932 Non-alcoholic fatty liver disease (NAFLD) 13/268 182/7206 0.025475431913 ko05145 Toxoplasmosis 10/268 126/7206 0.026714743029 ko04610 Complement and coagulation cascades 7/268 79/7206 0.0270216959226 ko04810 Regulation of actin cytoskeleton 17/268 264/7206 0.0287920359223 ko05132 Salmonella infection 8/268 98/7206 0.0289889136399 ko04630 Jak-STAT signaling pathway 10/268 132/7206 0.0313077047747 ko04140 Autophagy - animal 1/268 164/7206 0.0328465696501 ko04550 Signaling pathways regulating pluripotency of stem cells 1/268 165/7206 0.0332216136195 ko00680 Methane metabolism 4/268 34/7206 0.0361303109745 ko00500 Starch and sucrose metabolism 4/268 35/7206 0.0396418400441 ko04218 Cellular senescence 12/268 177/7206 0.0409849685803 ko04022 cGMP-PKG signaling pathway 14/268 216/7206 0.0415919439536 ko03040 Spliceosome 1/268 145/7206 0.0450344178117 ko04142 Lysosome 1/268 151/7206 0.0462087748583 ko04724 Glutamatergic synapse 1/268 152/7206 0.0466013633061 ko04666 Fc gamma R-mediated phagocytosis 9/268 122/7206 0.0469942123378 ko04920 Adipocytokine signaling pathway 7/268 89/7206 0.0471634336082 ko04660 T cell receptor signaling pathway 9/268 124/7206 0.0497544571487