ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	171/1025	423/7206	5.30646759238e-43
ko05033	Nicotine addiction	46/1025	56/7206	3.83805179414e-30
ko04724	Glutamatergic synapse	80/1025	152/7206	1.33618631798e-29
ko05032	Morphine addiction	61/1025	110/7206	2.12555897262e-24
ko04727	GABAergic synapse	58/1025	110/7206	9.00000296834e-22
ko04713	Circadian entrainment	64/1025	136/7206	1.80197396729e-20
ko04728	Dopaminergic synapse	77/1025	185/7206	2.38383850341e-20
ko04721	Synaptic vesicle cycle	46/1025	80/7206	1.50324253273e-19
ko04725	Cholinergic synapse	67/1025	160/7206	5.26045865566e-18
ko04723	Retrograde endocannabinoid signaling	70/1025	175/7206	1.81927730673e-17
ko04024	cAMP signaling pathway	90/1025	279/7206	6.04959293471e-15
ko04020	Calcium signaling pathway	83/1025	265/7206	5.06484009585e-13
ko04742	Taste transduction	32/1025	61/7206	1.73256101526e-12
ko04726	Serotonergic synapse	51/1025	137/7206	1.22545976308e-11
ko04911	Insulin secretion	46/1025	117/7206	1.40079215964e-11
ko04921	Oxytocin signaling pathway	67/1025	209/7206	2.61413238153e-11
ko04261	Adrenergic signaling in cardiomyocytes	64/1025	205/7206	3.1916265394e-10
ko05031	Amphetamine addiction	37/1025	91/7206	4.6288814911e-10
ko04744	Phototransduction	21/1025	36/7206	8.93811622977e-10
ko04360	Axon guidance	67/1025	233/7206	4.87847102475e-09
ko04720	Long-term potentiation	37/1025	99/7206	7.40288346694e-09
ko03040	Spliceosome	1/1025	145/7206	9.30051134402e-09
ko05203	Viral carcinogenesis	12/1025	277/7206	8.97190322431e-08
ko04970	Salivary secretion	34/1025	95/7206	1.04420789734e-07
ko04060	Cytokine-cytokine receptor interaction	6/1025	191/7206	4.70976922603e-07
ko04966	Collecting duct acid secretion	14/1025	26/7206	2.30999857578e-06
ko05322	Systemic lupus erythematosus	4/1025	151/7206	2.6463188655e-06
ko05030	Cocaine addiction	26/1025	73/7206	3.66457064205e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1025	74/7206	4.89782042306e-06
ko05168	Herpes simplex infection	7/1025	182/7206	7.24661845577e-06
ko03013	RNA transport	6/1025	166/7206	8.54178903762e-06
ko05164	Influenza A	6/1025	167/7206	8.63344854806e-06
ko04740	Olfactory transduction	27/1025	80/7206	1.20433648421e-05
ko04971	Gastric acid secretion	31/1025	98/7206	1.23055658309e-05
ko04925	Aldosterone synthesis and secretion	32/1025	105/7206	1.47553467598e-05
ko04745	Phototransduction - fly	16/1025	38/7206	2.54279224315e-05
ko04070	Phosphatidylinositol signaling system	33/1025	112/7206	2.69482357017e-05
ko04022	cGMP-PKG signaling pathway	53/1025	216/7206	4.15351141944e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/1025	79/7206	6.21525192846e-05
ko04141	Protein processing in endoplasmic reticulum	9/1025	184/7206	6.25579769521e-05
ko04120	Ubiquitin mediated proteolysis	5/1025	138/7206	6.30606554811e-05
ko04621	NOD-like receptor signaling pathway	7/1025	157/7206	0.000111038146725
ko04514	Cell adhesion molecules (CAMs)	35/1025	130/7206	0.000115962033778
ko03008	Ribosome biogenesis in eukaryotes	1/1025	79/7206	0.000129382809925
ko04014	Ras signaling pathway	63/1025	279/7206	0.000150623774314
ko04010	MAPK signaling pathway	70/1025	321/7206	0.00015766198141
ko04730	Long-term depression	24/1025	78/7206	0.000214583891191
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/1025	14/7206	0.000220543245971
ko04924	Renin secretion	25/1025	86/7206	0.00028652621608
ko04972	Pancreatic secretion	30/1025	111/7206	0.000319102614758
ko04540	Gap junction	33/1025	128/7206	0.000476158567041
ko05169	Epstein-Barr virus infection	13/1025	206/7206	0.000515825012423
ko05205	Proteoglycans in cancer	20/1025	271/7206	0.000517744182949
ko04064	NF-kappa B signaling pathway	3/1025	96/7206	0.000570716700016
ko04260	Cardiac muscle contraction	27/1025	98/7206	0.000624126809257
ko04072	Phospholipase D signaling pathway	45/1025	197/7206	0.000881060868916
ko05140	Leishmaniasis	2/1025	75/7206	0.00138574174089
ko05161	Hepatitis B	11/1025	173/7206	0.00184937434241
ko04626	Plant-pathogen interaction	8/1025	18/7206	0.00189344505639
ko05414	Dilated cardiomyopathy	28/1025	112/7206	0.00236148954972
ko05110	Vibrio cholerae infection	18/1025	63/7206	0.00296570953894
ko00480	Glutathione metabolism	1/1025	55/7206	0.00328586388054
ko04110	Cell cycle	9/1025	145/7206	0.0036489904246
ko00590	Arachidonic acid metabolism	1/1025	52/7206	0.00490732062962
ko04964	Proximal tubule bicarbonate reclamation	10/1025	29/7206	0.00497688811039
ko04612	Antigen processing and presentation	3/1025	77/7206	0.00498063062585
ko05162	Measles	7/1025	120/7206	0.00533676792626
ko04146	Peroxisome	4/1025	89/7206	0.00539676331478
ko00240	Pyrimidine metabolism	6/1025	110/7206	0.00549787042195
ko04640	Hematopoietic cell lineage	2/1025	64/7206	0.00628395619321
ko04915	Estrogen signaling pathway	30/1025	131/7206	0.00744819641161
ko04750	Inflammatory mediator regulation of TRP channels	28/1025	122/7206	0.00847426279791
ko00330	Arginine and proline metabolism	2/1025	61/7206	0.00910501283014
ko04976	Bile secretion	20/1025	80/7206	0.00928377024994
ko04214	Apoptosis - fly	3/1025	72/7206	0.010116478402
ko05219	Bladder cancer	1/1025	48/7206	0.0110743779515
ko05206	MicroRNAs in cancer	14/1025	177/7206	0.0120708107842
ko05166	HTLV-I infection	27/1025	292/7206	0.0128076652604
ko03022	Basal transcription factors	1/1025	44/7206	0.0160918273091
ko05144	Malaria	1/1025	45/7206	0.0163784763743
ko00071	Fatty acid degradation	1/1025	45/7206	0.0163784763743
ko04668	TNF signaling pathway	8/1025	120/7206	0.016729454857
ko03420	Nucleotide excision repair	1/1025	46/7206	0.0170679152086
ko04140	Autophagy - animal	13/1025	164/7206	0.0172321881223
ko04932	Non-alcoholic fatty liver disease (NAFLD)	15/1025	182/7206	0.017658548561
ko05321	Inflammatory bowel disease (IBD)	2/1025	56/7206	0.0192814689346
ko05410	Hypertrophic cardiomyopathy (HCM)	23/1025	100/7206	0.0197483522961
ko05145	Toxoplasmosis	9/1025	126/7206	0.0199083453036
ko01524	Platinum drug resistance	4/1025	76/7206	0.0202263320112
ko04371	Apelin signaling pathway	36/1025	177/7206	0.0220065212493
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/1025	59/7206	0.0224457239584
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/1025	92/7206	0.0234509603277
ko04510	Focal adhesion	22/1025	240/7206	0.0235770583633
ko00140	Steroid hormone biosynthesis	1/1025	41/7206	0.0238307207689
ko03018	RNA degradation	5/1025	84/7206	0.0268837715095
ko00310	Lysine degradation	4/1025	73/7206	0.0279352592433
ko04622	RIG-I-like receptor signaling pathway	3/1025	62/7206	0.0282710156186
ko00630	Glyoxylate and dicarboxylate metabolism	1/1025	38/7206	0.0352222167778
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1025	40/7206	0.0369141915505
ko05131	Shigellosis	5/1025	82/7206	0.0369567890448
ko04722	Neurotrophin signaling pathway	32/1025	160/7206	0.0391945922948
ko00380	Tryptophan metabolism	2/1025	50/7206	0.0395634095589
ko00910	Nitrogen metabolism	6/1025	19/7206	0.0426835303075