ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	34/712	56/7206	8.2979625424e-21
ko04080	Neuroactive ligand-receptor interaction	97/712	423/7206	2.89615741215e-16
ko04721	Synaptic vesicle cycle	35/712	80/7206	2.30912612119e-15
ko04724	Glutamatergic synapse	48/712	152/7206	6.33152057939e-14
ko04728	Dopaminergic synapse	54/712	185/7206	6.46837867792e-14
ko04360	Axon guidance	58/712	233/7206	1.24415222584e-11
ko05032	Morphine addiction	36/712	110/7206	2.9656659324e-11
ko04727	GABAergic synapse	35/712	110/7206	1.36524563132e-10
ko04713	Circadian entrainment	39/712	136/7206	3.92874359445e-10
ko04024	cAMP signaling pathway	60/712	279/7206	3.78315688412e-09
ko04723	Retrograde endocannabinoid signaling	42/712	175/7206	3.92448883e-08
ko05030	Cocaine addiction	23/712	73/7206	2.53469496299e-07
ko04725	Cholinergic synapse	37/712	160/7206	5.88598548933e-07
ko04514	Cell adhesion molecules (CAMs)	32/712	130/7206	7.32048731953e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	21/712	74/7206	5.5527538573e-06
ko03040	Spliceosome	1/712	145/7206	7.36471692774e-06
ko05031	Amphetamine addiction	23/712	91/7206	1.67403104669e-05
ko04911	Insulin secretion	27/712	117/7206	2.39759555442e-05
ko05203	Viral carcinogenesis	9/712	277/7206	3.24593493403e-05
ko01200	Carbon metabolism	1/712	128/7206	3.62075773416e-05
ko04742	Taste transduction	17/712	61/7206	5.56820273178e-05
ko03013	RNA transport	3/712	166/7206	5.79487334615e-05
ko04726	Serotonergic synapse	29/712	137/7206	6.29259773836e-05
ko04261	Adrenergic signaling in cardiomyocytes	38/712	205/7206	0.000115743526031
ko04010	MAPK signaling pathway	53/712	321/7206	0.00016396160455
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/712	14/7206	0.000164560362898
ko04391	Hippo signaling pathway - fly	20/712	90/7206	0.000469449858652
ko04060	Cytokine-cytokine receptor interaction	6/712	191/7206	0.000519398638854
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/712	79/7206	0.000802669135842
ko04964	Proximal tubule bicarbonate reclamation	9/712	29/7206	0.00138697240097
ko04260	Cardiac muscle contraction	20/712	98/7206	0.00163625907912
ko00240	Pyrimidine metabolism	2/712	110/7206	0.00180226011545
ko04921	Oxytocin signaling pathway	35/712	209/7206	0.00198083964146
ko04621	NOD-like receptor signaling pathway	5/712	157/7206	0.00257546610795
ko04970	Salivary secretion	19/712	95/7206	0.00260640009601
ko04966	Collecting duct acid secretion	8/712	26/7206	0.00271025878034
ko03018	RNA degradation	1/712	84/7206	0.00274495275652
ko01230	Biosynthesis of amino acids	1/712	85/7206	0.0027854148952
ko04120	Ubiquitin mediated proteolysis	4/712	138/7206	0.00344562448345
ko05322	Systemic lupus erythematosus	5/712	151/7206	0.00348333650309
ko05168	Herpes simplex infection	7/712	182/7206	0.00351052788652
ko05164	Influenza A	6/712	167/7206	0.00355246285541
ko04141	Protein processing in endoplasmic reticulum	7/712	184/7206	0.00360477217809
ko03008	Ribosome biogenesis in eukaryotes	1/712	79/7206	0.00403084724062
ko04950	Maturity onset diabetes of the young	8/712	29/7206	0.00570655760389
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/712	59/7206	0.00635535300422
ko05205	Proteoglycans in cancer	14/712	271/7206	0.00663697946846
ko04744	Phototransduction	9/712	36/7206	0.00695645579851
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/712	182/7206	0.00811320688259
ko04974	Protein digestion and absorption	18/712	96/7206	0.00839886598155
ko04214	Apoptosis - fly	1/712	72/7206	0.00873864616881
ko04211	Longevity regulating pathway	4/712	123/7206	0.00891582227407
ko04972	Pancreatic secretion	20/712	111/7206	0.0090967683334
ko00010	Glycolysis / Gluconeogenesis	1/712	74/7206	0.00914010615323
ko04720	Long-term potentiation	18/712	99/7206	0.00986177155004
ko04146	Peroxisome	2/712	89/7206	0.0109602874913
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	7/712	26/7206	0.0109982979623
ko04730	Long-term depression	15/712	78/7206	0.0112465015007
ko04140	Autophagy - animal	7/712	164/7206	0.0114090256931
ko04512	ECM-receptor interaction	15/712	79/7206	0.0120639199933
ko05169	Epstein-Barr virus infection	10/712	206/7206	0.0122766947198
ko05162	Measles	4/712	120/7206	0.0124835738399
ko04550	Signaling pathways regulating pluripotency of stem cells	26/712	165/7206	0.0165505204864
ko04913	Ovarian steroidogenesis	1/712	63/7206	0.0186349297815
ko00561	Glycerolipid metabolism	1/712	63/7206	0.0186349297815
ko05217	Basal cell carcinoma	13/712	68/7206	0.0214097694624
ko04138	Autophagy - yeast	2/712	81/7206	0.0223798839868
ko04064	NF-kappa B signaling pathway	3/712	96/7206	0.0234217890829
ko04014	Ras signaling pathway	39/712	279/7206	0.0239881413145
ko04390	Hippo signaling pathway	28/712	188/7206	0.0252003796796
ko05410	Hypertrophic cardiomyopathy (HCM)	17/712	100/7206	0.0261277712418
ko00330	Arginine and proline metabolism	1/712	61/7206	0.0279871308499
ko04217	Necroptosis	9/712	178/7206	0.0295358251989
ko04912	GnRH signaling pathway	5/712	122/7206	0.030660162967
ko05140	Leishmaniasis	2/712	75/7206	0.0309513854338
ko04066	HIF-1 signaling pathway	5/712	123/7206	0.0310686654847
ko00515	Mannose type O-glycan biosynthesis	6/712	25/7206	0.0314632890235
ko04612	Antigen processing and presentation	2/712	77/7206	0.0318416470304
ko05016	Huntington's disease	12/712	215/7206	0.0356602728008
ko05414	Dilated cardiomyopathy	18/712	112/7206	0.0363343765091
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/712	8/7206	0.0368295107702
ko00480	Glutathione metabolism	1/712	55/7206	0.0396807109589
ko05321	Inflammatory bowel disease (IBD)	1/712	56/7206	0.0400824916383
ko04071	Sphingolipid signaling pathway	24/712	162/7206	0.0442700109296
ko05133	Pertussis	3/712	87/7206	0.0446230678702