ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	194/1214	423/7206	3.02718683207e-47
ko04724	Glutamatergic synapse	86/1214	152/7206	2.8779628608e-29
ko05033	Nicotine addiction	46/1214	56/7206	8.00900829623e-27
ko05032	Morphine addiction	66/1214	110/7206	1.08909151849e-24
ko04727	GABAergic synapse	64/1214	110/7206	6.11230741713e-23
ko04713	Circadian entrainment	71/1214	136/7206	1.49244648051e-21
ko04728	Dopaminergic synapse	84/1214	185/7206	3.60984062184e-20
ko04725	Cholinergic synapse	76/1214	160/7206	8.74969131327e-20
ko04723	Retrograde endocannabinoid signaling	77/1214	175/7206	1.36078302568e-17
ko04024	cAMP signaling pathway	105/1214	279/7206	2.34085103122e-17
ko04726	Serotonergic synapse	63/1214	137/7206	9.82502480621e-16
ko04020	Calcium signaling pathway	96/1214	265/7206	8.23068478653e-15
ko04911	Insulin secretion	54/1214	117/7206	9.57964814762e-14
ko04742	Taste transduction	36/1214	61/7206	1.04440833793e-13
ko04721	Synaptic vesicle cycle	42/1214	80/7206	2.33599478343e-13
ko04921	Oxytocin signaling pathway	76/1214	209/7206	5.84015061204e-12
ko05031	Amphetamine addiction	41/1214	91/7206	2.40773222876e-10
ko04744	Phototransduction	23/1214	36/7206	3.32972409257e-10
ko04720	Long-term potentiation	42/1214	99/7206	1.43672024675e-09
ko03010	Ribosome	1/1214	129/7206	1.54051222428e-09
ko03040	Spliceosome	2/1214	145/7206	1.55573860843e-09
ko04261	Adrenergic signaling in cardiomyocytes	67/1214	205/7206	2.01877487734e-08
ko05322	Systemic lupus erythematosus	4/1214	151/7206	5.80800389912e-08
ko04970	Salivary secretion	38/1214	95/7206	8.10360770838e-08
ko04360	Axon guidance	72/1214	233/7206	9.31073281367e-08
ko04925	Aldosterone synthesis and secretion	40/1214	105/7206	2.05743850818e-07
ko05030	Cocaine addiction	30/1214	73/7206	7.40413145757e-07
ko04971	Gastric acid secretion	37/1214	98/7206	7.62397600277e-07
ko03013	RNA transport	8/1214	166/7206	2.89211045118e-06
ko04070	Phosphatidylinositol signaling system	39/1214	112/7206	2.94140692276e-06
ko05168	Herpes simplex infection	10/1214	182/7206	4.85256247132e-06
ko05203	Viral carcinogenesis	21/1214	277/7206	8.04860767154e-06
ko04621	NOD-like receptor signaling pathway	8/1214	157/7206	1.19362472353e-05
ko04730	Long-term depression	29/1214	78/7206	1.26115586706e-05
ko04010	MAPK signaling pathway	83/1214	321/7206	3.33036308143e-05
ko05164	Influenza A	10/1214	167/7206	3.6713410854e-05
ko04141	Protein processing in endoplasmic reticulum	12/1214	184/7206	3.73893238271e-05
ko04022	cGMP-PKG signaling pathway	60/1214	216/7206	4.19321811569e-05
ko04745	Phototransduction - fly	17/1214	38/7206	5.22210520767e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1214	74/7206	5.31508852636e-05
ko04014	Ras signaling pathway	73/1214	279/7206	5.77145335023e-05
ko04514	Cell adhesion molecules (CAMs)	40/1214	130/7206	7.45562589132e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1214	79/7206	0.000110056467541
ko04072	Phospholipase D signaling pathway	54/1214	197/7206	0.000149830890266
ko04972	Pancreatic secretion	35/1214	111/7206	0.000158786367076
ko04612	Antigen processing and presentation	2/1214	77/7206	0.000166311100226
ko04110	Cell cycle	9/1214	145/7206	0.000187033312487
ko04750	Inflammatory mediator regulation of TRP channels	37/1214	122/7206	0.0002035993561
ko04740	Olfactory transduction	27/1214	80/7206	0.000219440091329
ko04710	Circadian rhythm	17/1214	43/7206	0.000328944083952
ko04924	Renin secretion	28/1214	86/7206	0.000375348677101
ko04540	Gap junction	37/1214	128/7206	0.000724007121003
ko04976	Bile secretion	26/1214	80/7206	0.000734062519179
ko04060	Cytokine-cytokine receptor interaction	16/1214	191/7206	0.000820552459561
ko04915	Estrogen signaling pathway	37/1214	131/7206	0.000898624857088
ko05162	Measles	8/1214	120/7206	0.00130298585947
ko04964	Proximal tubule bicarbonate reclamation	12/1214	29/7206	0.0015444308758
ko04966	Collecting duct acid secretion	11/1214	26/7206	0.00195024092696
ko05169	Epstein-Barr virus infection	19/1214	206/7206	0.00235973655188
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/1214	79/7206	0.00350624622387
ko04120	Ubiquitin mediated proteolysis	11/1214	138/7206	0.00379605902634
ko03022	Basal transcription factors	1/1214	44/7206	0.00432242903848
ko05144	Malaria	1/1214	45/7206	0.0043270706018
ko03420	Nucleotide excision repair	1/1214	46/7206	0.00450926895424
ko05140	Leishmaniasis	4/1214	75/7206	0.00474233774496
ko05161	Hepatitis B	16/1214	173/7206	0.00531530863454
ko04626	Plant-pathogen interaction	8/1214	18/7206	0.00565186142393
ko04260	Cardiac muscle contraction	27/1214	98/7206	0.00645467033259
ko04217	Necroptosis	17/1214	178/7206	0.00801171222122
ko04064	NF-kappa B signaling pathway	7/1214	96/7206	0.00877284619734
ko04930	Type II diabetes mellitus	17/1214	54/7206	0.0090940818029
ko04657	IL-17 signaling pathway	6/1214	87/7206	0.00917382204214
ko04622	RIG-I-like receptor signaling pathway	3/1214	62/7206	0.00936430927738
ko04610	Complement and coagulation cascades	5/1214	79/7206	0.00947139333821
ko05231	Choline metabolism in cancer	34/1214	134/7206	0.0102553244793
ko04371	Apelin signaling pathway	43/1214	177/7206	0.0106451337089
ko04711	Circadian rhythm - fly	6/1214	13/7206	0.0132629382437
ko04672	Intestinal immune network for IgA production	1/1214	37/7206	0.0145781486127
ko03410	Base excision repair	1/1214	38/7206	0.0148121564933
ko05414	Dilated cardiomyopathy	29/1214	112/7206	0.0148943161085
ko04922	Glucagon signaling pathway	32/1214	128/7206	0.0168070046047
ko05131	Shigellosis	6/1214	82/7206	0.0171144287315
ko04015	Rap1 signaling pathway	62/1214	278/7206	0.0174680774902
ko04960	Aldosterone-regulated sodium reabsorption	13/1214	41/7206	0.0188601296834
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1214	14/7206	0.0199591456044
ko04923	Regulation of lipolysis in adipocytes	21/1214	77/7206	0.0205317422184
ko04142	Lysosome	15/1214	151/7206	0.0206186496038
ko04973	Carbohydrate digestion and absorption	13/1214	42/7206	0.0214033851352
ko04270	Vascular smooth muscle contraction	37/1214	154/7206	0.0216867995594
ko00500	Starch and sucrose metabolism	1/1214	35/7206	0.0218793281721
ko00071	Fatty acid degradation	2/1214	45/7206	0.025596579678
ko05016	Huntington's disease	24/1214	215/7206	0.0258890732865
ko00280	Valine, leucine and isoleucine degradation	3/1214	54/7206	0.0265305135858
ko04658	Th1 and Th2 cell differentiation	8/1214	96/7206	0.0268595685686
ko05133	Pertussis	7/1214	87/7206	0.0293283430138
ko05145	Toxoplasmosis	12/1214	126/7206	0.0297010203454
ko04916	Melanogenesis	34/1214	142/7206	0.0305879184353
ko00562	Inositol phosphate metabolism	23/1214	89/7206	0.0312783169478
ko00860	Porphyrin and chlorophyll metabolism	1/1214	34/7206	0.0345630484155
ko04932	Non-alcoholic fatty liver disease (NAFLD)	20/1214	182/7206	0.0345804550781
ko05166	HTLV-I infection	36/1214	292/7206	0.0375983222788
ko00590	Arachidonic acid metabolism	3/1214	52/7206	0.0381073281611
ko05205	Proteoglycans in cancer	33/1214	271/7206	0.0382667394633
ko03018	RNA degradation	7/1214	84/7206	0.0387874241063
ko05110	Vibrio cholerae infection	17/1214	63/7206	0.0408370469616
ko04115	p53 signaling pathway	6/1214	74/7206	0.0421654970087
ko04510	Focal adhesion	29/1214	240/7206	0.0437689918526
ko04146	Peroxisome	8/1214	89/7206	0.0458091975364
ko05321	Inflammatory bowel disease (IBD)	4/1214	56/7206	0.0491748646248
ko05214	Glioma	20/1214	79/7206	0.0492358494237
ko04912	GnRH signaling pathway	29/1214	122/7206	0.0498615994805