ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	171/1200	423/7206	1.81471162179e-33
ko04724	Glutamatergic synapse	73/1200	152/7206	1.08242900507e-19
ko04020	Calcium signaling pathway	99/1200	265/7206	1.2258901436e-16
ko05033	Nicotine addiction	36/1200	56/7206	1.52528963036e-15
ko04713	Circadian entrainment	60/1200	136/7206	2.88877210738e-14
ko04727	GABAergic synapse	51/1200	110/7206	2.36525996751e-13
ko05032	Morphine addiction	51/1200	110/7206	2.36525996751e-13
ko04921	Oxytocin signaling pathway	75/1200	209/7206	9.4293232942e-12
ko04024	cAMP signaling pathway	91/1200	279/7206	2.22767035032e-11
ko04728	Dopaminergic synapse	68/1200	185/7206	3.38699681307e-11
ko04725	Cholinergic synapse	59/1200	160/7206	4.66507184837e-10
ko04721	Synaptic vesicle cycle	37/1200	80/7206	5.21200701147e-10
ko04911	Insulin secretion	47/1200	117/7206	1.37458966692e-09
ko03010	Ribosome	1/1200	129/7206	2.51801364905e-09
ko04723	Retrograde endocannabinoid signaling	61/1200	175/7206	3.23027368565e-09
ko04726	Serotonergic synapse	51/1200	137/7206	4.43829110211e-09
ko04970	Salivary secretion	39/1200	95/7206	1.21366466163e-08
ko04022	cGMP-PKG signaling pathway	69/1200	216/7206	2.3433739608e-08
ko05031	Amphetamine addiction	37/1200	91/7206	3.90073311294e-08
ko04742	Taste transduction	28/1200	61/7206	8.23726951873e-08
ko04720	Long-term potentiation	38/1200	99/7206	1.69821005516e-07
ko03040	Spliceosome	4/1200	145/7206	1.93948003386e-07
ko04261	Adrenergic signaling in cardiomyocytes	63/1200	205/7206	4.82982652188e-07
ko03013	RNA transport	7/1200	166/7206	1.30617058352e-06
ko05203	Viral carcinogenesis	19/1200	277/7206	1.42748314974e-06
ko05322	Systemic lupus erythematosus	6/1200	151/7206	2.2287879847e-06
ko04971	Gastric acid secretion	35/1200	98/7206	3.7702343442e-06
ko04110	Cell cycle	6/1200	145/7206	4.57794139639e-06
ko04972	Pancreatic secretion	38/1200	111/7206	7.29085513941e-06
ko04925	Aldosterone synthesis and secretion	36/1200	105/7206	8.41985196241e-06
ko03008	Ribosome biogenesis in eukaryotes	1/1200	79/7206	1.28647808671e-05
ko04070	Phosphatidylinositol signaling system	37/1200	112/7206	1.70637484316e-05
ko04072	Phospholipase D signaling pathway	56/1200	197/7206	2.54844198733e-05
ko04730	Long-term depression	28/1200	78/7206	3.94211784242e-05
ko05030	Cocaine addiction	26/1200	73/7206	8.93051427622e-05
ko04514	Cell adhesion molecules (CAMs)	39/1200	130/7206	0.000121830632645
ko04120	Ubiquitin mediated proteolysis	8/1200	138/7206	0.00018700619714
ko04371	Apelin signaling pathway	49/1200	177/7206	0.000201265417657
ko04922	Glucagon signaling pathway	38/1200	128/7206	0.000265929949389
ko04710	Circadian rhythm	17/1200	43/7206	0.000285135626062
ko04010	MAPK signaling pathway	78/1200	321/7206	0.000303461236625
ko04966	Collecting duct acid secretion	12/1200	26/7206	0.00042130002668
ko00120	Primary bile acid biosynthesis	10/1200	20/7206	0.000582558490742
ko04745	Phototransduction - fly	15/1200	38/7206	0.000657266625773
ko04924	Renin secretion	27/1200	86/7206	0.00065802396791
ko04014	Ras signaling pathway	68/1200	279/7206	0.000739192582852
ko04750	Inflammatory mediator regulation of TRP channels	35/1200	122/7206	0.000808393589367
ko04270	Vascular smooth muscle contraction	42/1200	154/7206	0.000917718442708
ko04976	Bile secretion	25/1200	80/7206	0.00123588617813
ko03050	Proteasome	1/1200	54/7206	0.00133693381229
ko04964	Proximal tubule bicarbonate reclamation	12/1200	29/7206	0.00139106191965
ko05110	Vibrio cholerae infection	20/1200	63/7206	0.00318382536559
ko05168	Herpes simplex infection	16/1200	182/7206	0.00325518355648
ko05014	Amyotrophic lateral sclerosis (ALS)	22/1200	74/7206	0.00438606563883
ko03420	Nucleotide excision repair	1/1200	46/7206	0.00443521374016
ko04350	TGF-beta signaling pathway	7/1200	103/7206	0.00478175292273
ko04015	Rap1 signaling pathway	64/1200	278/7206	0.00511809833075
ko04744	Phototransduction	13/1200	36/7206	0.00517085422355
ko04626	Plant-pathogen interaction	8/1200	18/7206	0.00525252822027
ko04960	Aldosterone-regulated sodium reabsorption	14/1200	41/7206	0.00538746658145
ko00520	Amino sugar and nucleotide sugar metabolism	2/1200	55/7206	0.00563489226841
ko04260	Cardiac muscle contraction	27/1200	98/7206	0.00591936599116
ko04550	Signaling pathways regulating pluripotency of stem cells	15/1200	165/7206	0.00782495248607
ko04540	Gap junction	33/1200	128/7206	0.00802624799019
ko04141	Protein processing in endoplasmic reticulum	18/1200	184/7206	0.00905690319434
ko04214	Apoptosis - fly	4/1200	72/7206	0.00986318399755
ko05169	Epstein-Barr virus infection	21/1200	206/7206	0.0101823443055
ko04711	Circadian rhythm - fly	6/1200	13/7206	0.0125346494165
ko05323	Rheumatoid arthritis	24/1200	89/7206	0.0139652735426
ko05414	Dilated cardiomyopathy	29/1200	112/7206	0.0143068823089
ko03410	Base excision repair	1/1200	38/7206	0.0147558210834
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1200	100/7206	0.0148785454787
ko04930	Type II diabetes mellitus	16/1200	54/7206	0.0159177177032
ko05219	Bladder cancer	2/1200	48/7206	0.0177487583631
ko04923	Regulation of lipolysis in adipocytes	21/1200	77/7206	0.0196441302675
ko05224	Breast cancer	18/1200	174/7206	0.0230552195481
ko04011	MAPK signaling pathway - yeast	3/1200	53/7206	0.0261848743627
ko00562	Inositol phosphate metabolism	23/1200	89/7206	0.0302659515485
ko04360	Axon guidance	51/1200	233/7206	0.0320001149531
ko04915	Estrogen signaling pathway	31/1200	131/7206	0.0333031115318
ko04113	Meiosis - yeast	5/1200	70/7206	0.0344205781433
ko03015	mRNA surveillance pathway	8/1200	93/7206	0.0350627682714
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/1200	59/7206	0.0356093608336
ko04666	Fc gamma R-mediated phagocytosis	29/1200	122/7206	0.0373128067139
ko05220	Chronic myeloid leukemia	7/1200	85/7206	0.0390138458773
ko00010	Glycolysis / Gluconeogenesis	19/1200	74/7206	0.0415721781526
ko05205	Proteoglycans in cancer	33/1200	271/7206	0.0457874646537
ko04111	Cell cycle - yeast	8/1200	90/7206	0.0460456118912
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/1200	79/7206	0.0471310427185
ko05161	Hepatitis B	19/1200	173/7206	0.0488899305841
ko04740	Olfactory transduction	20/1200	80/7206	0.0497003199558