ko pathway ratio_in_study ratio_in_pop p_value ko04070 Phosphatidylinositol signaling system 11/105 112/7206 5.71196783876e-07 ko04720 Long-term potentiation 8/105 99/7206 8.89289472222e-05 ko04911 Insulin secretion 8/105 117/7206 0.000285435354549 ko04725 Cholinergic synapse 9/105 160/7206 0.000509366032917 ko04068 FoxO signaling pathway 9/105 167/7206 0.000695095593535 ko04925 Aldosterone synthesis and secretion 7/105 105/7206 0.000805973264182 ko04137 Mitophagy - animal 6/105 82/7206 0.00118525556163 ko00562 Inositol phosphate metabolism 6/105 89/7206 0.00181218691888 ko04912 GnRH signaling pathway 7/105 122/7206 0.00193885746319 ko04626 Plant-pathogen interaction 3/105 18/7206 0.00209214470491 ko04745 Phototransduction - fly 4/105 38/7206 0.00214694728865 ko04970 Salivary secretion 6/105 95/7206 0.00252666463868 ko04971 Gastric acid secretion 6/105 98/7206 0.0029547585087 ko04921 Oxytocin signaling pathway 9/105 209/7206 0.00330399591446 ko04713 Circadian entrainment 7/105 136/7206 0.00357939570315 ko04726 Serotonergic synapse 7/105 137/7206 0.00372780196251 ko04371 Apelin signaling pathway 8/105 177/7206 0.00415688066091 ko04919 Thyroid hormone signaling pathway 7/105 143/7206 0.00471905812106 ko04727 GABAergic synapse 6/105 110/7206 0.00522687132439 ko04750 Inflammatory mediator regulation of TRP channels 6/105 122/7206 0.00857861978244 ko05010 Alzheimer's disease 8/105 202/7206 0.00906263885485 ko00680 Methane metabolism 3/105 34/7206 0.0129644354548 ko04022 cGMP-PKG signaling pathway 8/105 216/7206 0.0132387693528 ko04723 Retrograde endocannabinoid signaling 7/105 175/7206 0.0136788518369 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/105 1/7206 0.0145711906745 ko04711 Circadian rhythm - fly 2/105 13/7206 0.0147737191083 ko04020 Calcium signaling pathway 9/105 265/7206 0.0148527506552 ko04744 Phototransduction 3/105 36/7206 0.0151486174059 ko04114 Oocyte meiosis 6/105 139/7206 0.0156472056722 ko04916 Melanogenesis 6/105 142/7206 0.017219443226 ko04728 Dopaminergic synapse 7/105 185/7206 0.018067366875 ko00010 Glycolysis / Gluconeogenesis 4/105 74/7206 0.0224815625651 ko05134 Legionellosis 4/105 74/7206 0.0224815625651 ko00051 Fructose and mannose metabolism 3/105 42/7206 0.0228786525699 ko04724 Glutamatergic synapse 6/105 152/7206 0.0232420511621 ko04270 Vascular smooth muscle contraction 6/105 154/7206 0.0245973519875 ko04721 Synaptic vesicle cycle 4/105 80/7206 0.0289375801372 ko04740 Olfactory transduction 4/105 80/7206 0.0289375801372 ko04722 Neurotrophin signaling pathway 6/105 160/7206 0.028978889845 ko04261 Adrenergic signaling in cardiomyocytes 7/105 205/7206 0.0296634059002 ko04071 Sphingolipid signaling pathway 6/105 162/7206 0.0305469587509 ko04140 Autophagy - animal 6/105 164/7206 0.0321698950224 ko04924 Renin secretion 4/105 86/7206 0.0363912219605 ko04918 Thyroid hormone synthesis 4/105 86/7206 0.0363912219605 ko00190 Oxidative phosphorylation 5/105 127/7206 0.0375201719269 ko04922 Glucagon signaling pathway 5/105 128/7206 0.0386089660811 ko04915 Estrogen signaling pathway 5/105 131/7206 0.0419910281379