ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	169/996	423/7206	1.91892889629e-43
ko04724	Glutamatergic synapse	81/996	152/7206	2.25532634585e-31
ko05033	Nicotine addiction	46/996	56/7206	1.04089545978e-30
ko05032	Morphine addiction	65/996	110/7206	7.07795668078e-29
ko04727	GABAergic synapse	62/996	110/7206	5.22678216438e-26
ko04728	Dopaminergic synapse	81/996	185/7206	6.34992295782e-24
ko04713	Circadian entrainment	67/996	136/7206	1.60745121497e-23
ko04723	Retrograde endocannabinoid signaling	75/996	175/7206	1.58303625325e-21
ko04721	Synaptic vesicle cycle	47/996	80/7206	5.02927524637e-21
ko04725	Cholinergic synapse	70/996	160/7206	8.96899400709e-21
ko04024	cAMP signaling pathway	93/996	279/7206	1.87584155664e-17
ko04742	Taste transduction	34/996	61/7206	1.33942952276e-14
ko04911	Insulin secretion	49/996	117/7206	5.57277481695e-14
ko04726	Serotonergic synapse	53/996	137/7206	2.50098360272e-13
ko04744	Phototransduction	24/996	36/7206	4.38104728081e-13
ko04921	Oxytocin signaling pathway	69/996	209/7206	5.69988054878e-13
ko04261	Adrenergic signaling in cardiomyocytes	67/996	205/7206	3.30545088438e-12
ko04020	Calcium signaling pathway	78/996	265/7206	1.80951795365e-11
ko05031	Amphetamine addiction	38/996	91/7206	4.38150602145e-11
ko04720	Long-term potentiation	39/996	99/7206	2.00496053886e-10
ko03040	Spliceosome	1/996	145/7206	1.43991447568e-08
ko05030	Cocaine addiction	29/996	73/7206	3.45450168278e-08
ko04925	Aldosterone synthesis and secretion	36/996	105/7206	7.37322704068e-08
ko04970	Salivary secretion	33/996	95/7206	1.8144049919e-07
ko04060	Cytokine-cytokine receptor interaction	6/996	191/7206	1.05626258337e-06
ko04010	MAPK signaling pathway	76/996	321/7206	1.2119433188e-06
ko05203	Viral carcinogenesis	14/996	277/7206	2.03901555291e-06
ko05168	Herpes simplex infection	6/996	182/7206	3.16178173856e-06
ko04360	Axon guidance	58/996	233/7206	4.31725074456e-06
ko04971	Gastric acid secretion	31/996	98/7206	4.61746476137e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/996	74/7206	9.80224094457e-06
ko03013	RNA transport	6/996	166/7206	1.84511241024e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/996	79/7206	1.85438277867e-05
ko04022	cGMP-PKG signaling pathway	53/996	216/7206	2.02242231982e-05
ko04740	Olfactory transduction	26/996	80/7206	2.07648829588e-05
ko05322	Systemic lupus erythematosus	5/996	151/7206	2.21544009274e-05
ko04120	Ubiquitin mediated proteolysis	4/996	138/7206	2.69317030098e-05
ko04141	Protein processing in endoplasmic reticulum	8/996	184/7206	3.15277660743e-05
ko04260	Cardiac muscle contraction	29/996	98/7206	4.23497314177e-05
ko04621	NOD-like receptor signaling pathway	6/996	157/7206	5.32311159591e-05
ko05164	Influenza A	7/996	167/7206	5.76897699251e-05
ko04966	Collecting duct acid secretion	12/996	26/7206	6.77115713805e-05
ko04972	Pancreatic secretion	31/996	111/7206	7.65908662334e-05
ko04514	Cell adhesion molecules (CAMs)	35/996	130/7206	8.55842815586e-05
ko04730	Long-term depression	24/996	78/7206	9.13673311988e-05
ko04072	Phospholipase D signaling pathway	47/996	197/7206	0.000136077546985
ko05414	Dilated cardiomyopathy	30/996	112/7206	0.000255109594374
ko04070	Phosphatidylinositol signaling system	30/996	112/7206	0.000255109594374
ko05110	Vibrio cholerae infection	20/996	63/7206	0.000280410162773
ko04745	Phototransduction - fly	14/996	38/7206	0.000322664647498
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/996	59/7206	0.000380267715441
ko05205	Proteoglycans in cancer	19/996	271/7206	0.000444930984054
ko04915	Estrogen signaling pathway	33/996	131/7206	0.000462274825321
ko04064	NF-kappa B signaling pathway	3/996	96/7206	0.000851552465285
ko05161	Hepatitis B	10/996	173/7206	0.00109332687075
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/996	14/7206	0.0013332503073
ko04612	Antigen processing and presentation	2/996	77/7206	0.00141976502125
ko03008	Ribosome biogenesis in eukaryotes	2/996	79/7206	0.00146271564214
ko04640	Hematopoietic cell lineage	1/996	64/7206	0.00153001438694
ko04014	Ras signaling pathway	57/996	279/7206	0.00187071693858
ko05140	Leishmaniasis	2/996	75/7206	0.00208147233748
ko04110	Cell cycle	8/996	145/7206	0.00213717112062
ko04540	Gap junction	30/996	128/7206	0.00276133308158
ko05162	Measles	6/996	120/7206	0.00299330177205
ko04750	Inflammatory mediator regulation of TRP channels	29/996	122/7206	0.00318980405718
ko05169	Epstein-Barr virus infection	15/996	206/7206	0.00400887531389
ko00480	Glutathione metabolism	1/996	55/7206	0.00505184347772
ko05410	Hypertrophic cardiomyopathy (HCM)	24/996	100/7206	0.00522041584984
ko04371	Apelin signaling pathway	38/996	177/7206	0.00545984971482
ko04630	Jak-STAT signaling pathway	8/996	132/7206	0.00704830968701
ko04924	Renin secretion	21/996	86/7206	0.00708314401602
ko00240	Pyrimidine metabolism	6/996	110/7206	0.00764450486855
ko04146	Peroxisome	4/996	89/7206	0.0077711751495
ko04976	Bile secretion	20/996	80/7206	0.0080157342535
ko00260	Glycine, serine and threonine metabolism	1/996	48/7206	0.0110083851152
ko04964	Proximal tubule bicarbonate reclamation	9/996	29/7206	0.0133447969891
ko00330	Arginine and proline metabolism	2/996	61/7206	0.0137223050618
ko04350	TGF-beta signaling pathway	6/996	103/7206	0.0140685077281
ko04210	Apoptosis	14/996	180/7206	0.0156997828717
ko04930	Type II diabetes mellitus	14/996	54/7206	0.0159657117504
ko00071	Fatty acid degradation	1/996	45/7206	0.016316572394
ko03420	Nucleotide excision repair	1/996	46/7206	0.0164914637111
ko04670	Leukocyte transendothelial migration	11/996	151/7206	0.0166664760079
ko05215	Prostate cancer	7/996	111/7206	0.017875706795
ko05321	Inflammatory bowel disease (IBD)	2/996	56/7206	0.0192063512524
ko04217	Necroptosis	14/996	178/7206	0.0202364667071
ko03320	PPAR signaling pathway	3/996	69/7206	0.0208838788865
ko03022	Basal transcription factors	1/996	44/7206	0.0251682928708
ko04658	Th1 and Th2 cell differentiation	6/996	96/7206	0.0256138709523
ko05145	Toxoplasmosis	9/996	126/7206	0.0263274979225
ko04657	IL-17 signaling pathway	5/996	87/7206	0.0273721704389
ko05034	Alcoholism	45/996	238/7206	0.0274617781742
ko00280	Valine, leucine and isoleucine degradation	2/996	54/7206	0.0277272169263
ko01524	Platinum drug resistance	4/996	76/7206	0.0284648205921
ko04140	Autophagy - animal	13/996	164/7206	0.0287985369497
ko04932	Non-alcoholic fatty liver disease (NAFLD)	15/996	182/7206	0.0288234293648
ko04626	Plant-pathogen interaction	6/996	18/7206	0.029106379385
ko05166	HTLV-I infection	28/996	292/7206	0.0304678939174
ko04114	Oocyte meiosis	28/996	139/7206	0.0345411524747
ko04510	Focal adhesion	22/996	240/7206	0.0358019629003
ko00980	Metabolism of xenobiotics by cytochrome P450	1/996	40/7206	0.035986942008
ko00140	Steroid hormone biosynthesis	1/996	41/7206	0.0370905384221
ko03018	RNA degradation	5/996	84/7206	0.0371395713038
ko04062	Chemokine signaling pathway	38/996	201/7206	0.0381197339154
ko04214	Apoptosis - fly	4/996	72/7206	0.0388329932033
ko00310	Lysine degradation	4/996	73/7206	0.0391446660802
ko04115	p53 signaling pathway	4/996	74/7206	0.0398912968033
ko04622	RIG-I-like receptor signaling pathway	3/996	62/7206	0.0402540540916
ko04923	Regulation of lipolysis in adipocytes	17/996	77/7206	0.0447463886276
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/996	15/7206	0.0454281289867
ko04912	GnRH signaling pathway	25/996	122/7206	0.0456781176901