ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 22/215 79/7206 4.19285556956e-16 ko05410 Hypertrophic cardiomyopathy (HCM) 24/215 100/7206 7.5309330511e-16 ko04974 Protein digestion and absorption 21/215 96/7206 3.84114924992e-13 ko05414 Dilated cardiomyopathy 22/215 112/7206 1.063792727e-12 ko04510 Focal adhesion 31/215 240/7206 2.7573168215e-12 ko04260 Cardiac muscle contraction 17/215 98/7206 3.37423262155e-09 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 15/215 79/7206 8.0799859263e-09 ko01200 Carbon metabolism 15/215 128/7206 5.42197296663e-06 ko04261 Adrenergic signaling in cardiomyocytes 19/215 205/7206 1.01931923172e-05 ko05416 Viral myocarditis 9/215 55/7206 3.05518102311e-05 ko04151 PI3K-Akt signaling pathway 27/215 390/7206 3.84246166394e-05 ko00010 Glycolysis / Gluconeogenesis 10/215 74/7206 6.13230226624e-05 ko04020 Calcium signaling pathway 19/215 265/7206 0.000333677636904 ko00680 Methane metabolism 6/215 34/7206 0.000439479345768 ko04921 Oxytocin signaling pathway 15/215 209/7206 0.00140300622365 ko00030 Pentose phosphate pathway 5/215 32/7206 0.00235441800386 ko04810 Regulation of actin cytoskeleton 17/215 264/7206 0.00252305361975 ko05146 Amoebiasis 9/215 99/7206 0.00267724002311 ko00020 Citrate cycle (TCA cycle) 5/215 35/7206 0.00353022530733 ko04022 cGMP-PKG signaling pathway 14/215 216/7206 0.00638480475033 ko00710 Carbon fixation in photosynthetic organisms 4/215 27/7206 0.00788798242941 ko05205 Proteoglycans in cancer 16/215 271/7206 0.00916316564182 ko04964 Proximal tubule bicarbonate reclamation 4/215 29/7206 0.0101914479859 ko00620 Pyruvate metabolism 5/215 46/7206 0.0114447160975 ko01230 Biosynthesis of amino acids 7/215 85/7206 0.0131609839232 ko00051 Fructose and mannose metabolism 4/215 42/7206 0.0356196360779 ko04010 MAPK signaling pathway 16/215 321/7206 0.0417764098949 ko05144 Malaria 4/215 45/7206 0.0442822576992 ko04728 Dopaminergic synapse 1/215 185/7206 0.0457108272856 ko05152 Tuberculosis 1/215 187/7206 0.0461306204017