ko pathway ratio_in_study ratio_in_pop p_value ko05164 Influenza A 22/190 167/7206 3.27555121501e-10 ko04621 NOD-like receptor signaling pathway 20/190 157/7206 4.00778546798e-09 ko04380 Osteoclast differentiation 18/190 134/7206 1.07293249732e-08 ko04060 Cytokine-cytokine receptor interaction 21/190 191/7206 2.32547252194e-08 ko05145 Toxoplasmosis 17/190 126/7206 2.62463674513e-08 ko05152 Tuberculosis 20/190 187/7206 8.1841842144e-08 ko04217 Necroptosis 19/190 178/7206 1.81760432782e-07 ko05140 Leishmaniasis 12/190 75/7206 4.87512171347e-07 ko05162 Measles 15/190 120/7206 4.97413008704e-07 ko05321 Inflammatory bowel disease (IBD) 10/190 56/7206 1.59040937881e-06 ko05168 Herpes simplex infection 17/190 182/7206 5.33668962381e-06 ko04064 NF-kappa B signaling pathway 12/190 96/7206 7.1834490212e-06 ko04650 Natural killer cell mediated cytotoxicity 12/190 97/7206 8.01085881574e-06 ko04630 Jak-STAT signaling pathway 14/190 132/7206 8.70468177827e-06 ko04623 Cytosolic DNA-sensing pathway 8/190 41/7206 9.13410164085e-06 ko05340 Primary immunodeficiency 7/190 30/7206 9.65600122882e-06 ko04620 Toll-like receptor signaling pathway 12/190 100/7206 1.10159829673e-05 ko04660 T cell receptor signaling pathway 13/190 124/7206 2.08721331501e-05 ko04622 RIG-I-like receptor signaling pathway 9/190 62/7206 3.09116834705e-05 ko04658 Th1 and Th2 cell differentiation 11/190 96/7206 4.00487207488e-05 ko04668 TNF signaling pathway 12/190 120/7206 6.97677145156e-05 ko05133 Pertussis 10/190 87/7206 8.79378544948e-05 ko04662 B cell receptor signaling pathway 10/190 88/7206 9.69728797485e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 15/190 191/7206 0.000145358970083 ko04612 Antigen processing and presentation 9/190 77/7206 0.00017487006667 ko05161 Hepatitis B 14/190 173/7206 0.000177217620626 ko04062 Chemokine signaling pathway 15/190 201/7206 0.000255257329931 ko05150 Staphylococcus aureus infection 6/190 36/7206 0.000312727725413 ko04672 Intestinal immune network for IgA production 6/190 37/7206 0.000365172507249 ko04659 Th17 cell differentiation 10/190 106/7206 0.000454018688085 ko05160 Hepatitis C 12/190 153/7206 0.000684191285914 ko04611 Platelet activation 12/190 163/7206 0.0011957603809 ko00590 Arachidonic acid metabolism 6/190 52/7206 0.00230534429338 ko04664 Fc epsilon RI signaling pathway 7/190 77/7206 0.00401793222474 ko05132 Salmonella infection 8/190 98/7206 0.00418595281652 ko05166 HTLV-I infection 16/190 292/7206 0.00466173634662 ko04080 Neuroactive ligand-receptor interaction 3/190 423/7206 0.00698347023836 ko05142 Chagas disease (American trypanosomiasis) 9/190 130/7206 0.00722438961172 ko04210 Apoptosis 11/190 180/7206 0.00786775035752 ko05323 Rheumatoid arthritis 7/190 89/7206 0.00884436441533 ko05310 Asthma 3/190 17/7206 0.00934111566596 ko05134 Legionellosis 6/190 74/7206 0.0130353865014 ko04666 Fc gamma R-mediated phagocytosis 8/190 122/7206 0.0150393350822 ko04610 Complement and coagulation cascades 6/190 79/7206 0.0175678239214 ko04670 Leukocyte transendothelial migration 9/190 151/7206 0.0181045022793 ko05131 Shigellosis 6/190 82/7206 0.0207530760519 ko05034 Alcoholism 1/190 238/7206 0.0219214597423 ko05169 Epstein-Barr virus infection 11/190 206/7206 0.0238101007369 ko00051 Fructose and mannose metabolism 4/190 42/7206 0.0240145953164 ko05330 Allograft rejection 3/190 24/7206 0.0243009173482 ko00966 Glucosinolate biosynthesis 1/190 1/7206 0.0263669164585 ko04145 Phagosome 9/190 162/7206 0.0396895405275 ko05320 Autoimmune thyroid disease 3/190 29/7206 0.0398802047151 ko04072 Phospholipase D signaling pathway 10/190 197/7206 0.0399798259354 ko05016 Huntington's disease 1/190 215/7206 0.0470311472758