ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 37/263 191/7206 1.67594365016e-17 ko05164 Influenza A 32/263 167/7206 4.19420370574e-15 ko04650 Natural killer cell mediated cytotoxicity 23/263 97/7206 3.30718539867e-13 ko05168 Herpes simplex infection 31/263 182/7206 3.35403071103e-13 ko05340 Primary immunodeficiency 14/263 30/7206 4.55684600081e-13 ko05140 Leishmaniasis 20/263 75/7206 1.13929859326e-12 ko04621 NOD-like receptor signaling pathway 28/263 157/7206 1.57425622776e-12 ko05152 Tuberculosis 30/263 187/7206 4.14162876899e-12 ko05162 Measles 24/263 120/7206 5.23142298165e-12 ko05330 Allograft rejection 12/263 24/7206 7.97997158666e-12 ko04612 Antigen processing and presentation 19/263 77/7206 1.91801257977e-11 ko04659 Th17 cell differentiation 22/263 106/7206 1.93404549924e-11 ko05145 Toxoplasmosis 23/263 126/7206 1.05406557987e-10 ko05332 Graft-versus-host disease 10/263 18/7206 1.19774583246e-10 ko05320 Autoimmune thyroid disease 12/263 29/7206 1.30044872095e-10 ko05321 Inflammatory bowel disease (IBD) 15/263 56/7206 7.75174799622e-10 ko04380 Osteoclast differentiation 22/263 134/7206 2.25224200839e-09 ko04620 Toll-like receptor signaling pathway 19/263 100/7206 2.3471502139e-09 ko04658 Th1 and Th2 cell differentiation 18/263 96/7206 7.8394258118e-09 ko04217 Necroptosis 24/263 178/7206 2.3407288345e-08 ko04640 Hematopoietic cell lineage 14/263 64/7206 4.91394365668e-08 ko04064 NF-kappa B signaling pathway 17/263 96/7206 5.04636796307e-08 ko05310 Asthma 8/263 17/7206 5.17564652305e-08 ko04062 Chemokine signaling pathway 25/263 201/7206 6.07548154004e-08 ko04145 Phagosome 22/263 162/7206 8.12408516815e-08 ko04660 T cell receptor signaling pathway 19/263 124/7206 9.22179785527e-08 ko04940 Type I diabetes mellitus 10/263 32/7206 1.12177075234e-07 ko04672 Intestinal immune network for IgA production 10/263 37/7206 5.15227488962e-07 ko04630 Jak-STAT signaling pathway 18/263 132/7206 1.2043892326e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 22/263 191/7206 1.48417547112e-06 ko05150 Staphylococcus aureus infection 9/263 36/7206 3.97029921481e-06 ko04622 RIG-I-like receptor signaling pathway 11/263 62/7206 1.20707727109e-05 ko04623 Cytosolic DNA-sensing pathway 9/263 41/7206 1.25868134479e-05 ko05133 Pertussis 13/263 87/7206 1.38453526715e-05 ko05161 Hepatitis B 19/263 173/7206 1.57845938968e-05 ko04662 B cell receptor signaling pathway 12/263 88/7206 7.52372152808e-05 ko05323 Rheumatoid arthritis 12/263 89/7206 8.41849841649e-05 ko03050 Proteasome 9/263 54/7206 0.000126074648202 ko05160 Hepatitis C 16/263 153/7206 0.000134456664044 ko05416 Viral myocarditis 9/263 55/7206 0.00014600703936 ko05144 Malaria 8/263 45/7206 0.000188548087561 ko05142 Chagas disease (American trypanosomiasis) 14/263 130/7206 0.000259216023355 ko04610 Complement and coagulation cascades 10/263 79/7206 0.000551327884281 ko04514 Cell adhesion molecules (CAMs) 13/263 130/7206 0.000873633715978 ko04666 Fc gamma R-mediated phagocytosis 12/263 122/7206 0.00158219988247 ko04664 Fc epsilon RI signaling pathway 9/263 77/7206 0.00184062361969 ko05016 Huntington's disease 1/263 215/7206 0.00495168551778 ko05166 HTLV-I infection 20/263 292/7206 0.00605750782122 ko04210 Apoptosis 14/263 180/7206 0.00711728566067 ko04611 Platelet activation 13/263 163/7206 0.00864778202038 ko05132 Salmonella infection 9/263 98/7206 0.00925783617554 ko05131 Shigellosis 8/263 82/7206 0.00977009876374 ko05146 Amoebiasis 9/263 99/7206 0.0098688215808 ko00590 Arachidonic acid metabolism 6/263 52/7206 0.0111188379185 ko04668 TNF signaling pathway 10/263 120/7206 0.0120476977357 ko04310 Wnt signaling pathway 1/263 181/7206 0.0150793439657 ko04390 Hippo signaling pathway 1/263 188/7206 0.0156556840596 ko04144 Endocytosis 21/263 342/7206 0.017303598762 ko04360 Axon guidance 2/263 233/7206 0.0186954366812 ko05169 Epstein-Barr virus infection 14/263 206/7206 0.0220772657876 ko05143 African trypanosomiasis 4/263 32/7206 0.0279320989582 ko04550 Signaling pathways regulating pluripotency of stem cells 1/263 165/7206 0.0322242282197 ko05010 Alzheimer's disease 2/263 202/7206 0.0351135917959 ko04080 Neuroactive ligand-receptor interaction 8/263 423/7206 0.0446361886895 ko04724 Glutamatergic synapse 1/263 152/7206 0.0456679247576