ko pathway ratio_in_study ratio_in_pop p_value ko04137 Mitophagy - animal 20/534 82/7206 1.40854528637e-06 ko04650 Natural killer cell mediated cytotoxicity 21/534 97/7206 6.02871838531e-06 ko04710 Circadian rhythm 13/534 43/7206 8.10147451862e-06 ko04146 Peroxisome 19/534 89/7206 2.06093597851e-05 ko05340 Primary immunodeficiency 9/534 30/7206 0.000219618473164 ko04138 Autophagy - yeast 16/534 81/7206 0.000240762669005 ko04136 Autophagy - other 9/534 31/7206 0.000289430820515 ko03040 Spliceosome 1/534 145/7206 0.000307881147296 ko00120 Primary bile acid biosynthesis 7/534 20/7206 0.000390005836212 ko04060 Cytokine-cytokine receptor interaction 28/534 191/7206 0.00040162958445 ko03013 RNA transport 2/534 166/7206 0.000454882358046 ko05034 Alcoholism 5/534 238/7206 0.000561885721606 ko00010 Glycolysis / Gluconeogenesis 14/534 74/7206 0.000914791682755 ko03010 Ribosome 1/534 129/7206 0.000981718516294 ko00071 Fatty acid degradation 10/534 45/7206 0.00137076447707 ko04022 cGMP-PKG signaling pathway 29/534 216/7206 0.00144302100362 ko04068 FoxO signaling pathway 24/534 167/7206 0.00146317248162 ko01200 Carbon metabolism 20/534 128/7206 0.00163456235061 ko00620 Pyruvate metabolism 10/534 46/7206 0.0016379540645 ko04610 Complement and coagulation cascades 14/534 79/7206 0.00177193805725 ko04110 Cell cycle 2/534 145/7206 0.00197612120563 ko04640 Hematopoietic cell lineage 12/534 64/7206 0.00226159721691 ko00051 Fructose and mannose metabolism 9/534 42/7206 0.00307755544798 ko04922 Glucagon signaling pathway 19/534 128/7206 0.00318592119549 ko01212 Fatty acid metabolism 11/534 60/7206 0.00408225899245 ko05150 Staphylococcus aureus infection 8/534 36/7206 0.00408614352733 ko04672 Intestinal immune network for IgA production 8/534 37/7206 0.00488321208251 ko04660 T cell receptor signaling pathway 18/534 124/7206 0.00504003404446 ko00362 Benzoate degradation 3/534 6/7206 0.0068311665919 ko05330 Allograft rejection 6/534 24/7206 0.00684569682723 ko05152 Tuberculosis 24/534 187/7206 0.00690391573727 ko04659 Th17 cell differentiation 16/534 106/7206 0.00729119902613 ko00592 alpha-Linolenic acid metabolism 5/534 19/7206 0.010662353523 ko05167 Kaposi's sarcoma-associated herpesvirus infection 24/534 191/7206 0.0107822685978 ko00640 Propanoate metabolism 7/534 34/7206 0.0109361525179 ko00680 Methane metabolism 7/534 34/7206 0.0109361525179 ko04380 Osteoclast differentiation 18/534 134/7206 0.0118061845052 ko00330 Arginine and proline metabolism 10/534 61/7206 0.0133424670126 ko04611 Platelet activation 21/534 163/7206 0.0141306293296 ko04140 Autophagy - animal 21/534 164/7206 0.0144531870343 ko05144 Malaria 8/534 45/7206 0.0161991830619 ko03320 PPAR signaling pathway 11/534 69/7206 0.0166939865907 ko05230 Central carbon metabolism in cancer 12/534 81/7206 0.0173749207299 ko05320 Autoimmune thyroid disease 6/534 29/7206 0.0176351989295 ko04371 Apelin signaling pathway 22/534 177/7206 0.0186493928725 ko00270 Cysteine and methionine metabolism 8/534 47/7206 0.0207648530038 ko04066 HIF-1 signaling pathway 16/534 123/7206 0.023221127133 ko05203 Viral carcinogenesis 11/534 277/7206 0.0254182501796 ko04070 Phosphatidylinositol signaling system 15/534 112/7206 0.0263276645518 ko04010 MAPK signaling pathway 14/534 321/7206 0.0292446165068 ko04658 Th1 and Th2 cell differentiation 13/534 96/7206 0.0292864506735 ko04921 Oxytocin signaling pathway 24/534 209/7206 0.0307940254164 ko00350 Tyrosine metabolism 6/534 33/7206 0.032030460422 ko05310 Asthma 4/534 17/7206 0.0326908453094 ko00360 Phenylalanine metabolism 4/534 17/7206 0.0326908453094 ko00950 Isoquinoline alkaloid biosynthesis 3/534 10/7206 0.0327808063624 ko01040 Biosynthesis of unsaturated fatty acids 5/534 25/7206 0.0337708811921 ko05321 Inflammatory bowel disease (IBD) 9/534 56/7206 0.0339978675068 ko05145 Toxoplasmosis 16/534 126/7206 0.0366522652908 ko05332 Graft-versus-host disease 4/534 18/7206 0.0396438510163 ko05224 Breast cancer 6/534 174/7206 0.0399346340013 ko00710 Carbon fixation in photosynthetic organisms 5/534 27/7206 0.0454665591278 ko03015 mRNA surveillance pathway 2/534 93/7206 0.046129869259 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/534 5/7206 0.0471623258998