ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 23/348 68/7206 2.87538574525e-14 ko04340 Hedgehog signaling pathway 17/348 58/7206 9.24956114207e-10 ko05224 Breast cancer 29/348 174/7206 3.2405255656e-09 ko04550 Signaling pathways regulating pluripotency of stem cells 28/348 165/7206 4.03698154348e-09 ko05205 Proteoglycans in cancer 34/348 271/7206 2.25009285826e-07 ko04390 Hippo signaling pathway 27/348 188/7206 2.82999034199e-07 ko04080 Neuroactive ligand-receptor interaction 3/348 423/7206 1.76889907685e-06 ko05200 Pathways in cancer 48/348 492/7206 1.9075489412e-06 ko04330 Notch signaling pathway 13/348 62/7206 6.00193327302e-06 ko04950 Maturity onset diabetes of the young 8/348 29/7206 4.79563884817e-05 ko04310 Wnt signaling pathway 22/348 181/7206 5.43292137143e-05 ko04612 Antigen processing and presentation 13/348 77/7206 6.87690704655e-05 ko04350 TGF-beta signaling pathway 15/348 103/7206 0.000112807846904 ko05418 Fluid shear stress and atherosclerosis 19/348 173/7206 0.000815589953121 ko04020 Calcium signaling pathway 3/348 265/7206 0.00183467396676 ko01522 Endocrine resistance 14/348 124/7206 0.00250491212074 ko05222 Small cell lung cancer 11/348 89/7206 0.00352387551757 ko05202 Transcriptional misregulation in cancer 18/348 188/7206 0.00499790342374 ko05012 Parkinson's disease 1/348 155/7206 0.00707077043193 ko04341 Hedgehog signaling pathway - fly 6/348 38/7206 0.00904574989529 ko04144 Endocytosis 7/348 342/7206 0.00951955739265 ko04724 Glutamatergic synapse 1/348 152/7206 0.0108886043473 ko04391 Hippo signaling pathway - fly 10/348 90/7206 0.0111131456299 ko00514 Other types of O-glycan biosynthesis 5/348 30/7206 0.0134196141953 ko04931 Insulin resistance 1/348 137/7206 0.0147877270344 ko04120 Ubiquitin mediated proteolysis 1/348 138/7206 0.0148246481523 ko05206 MicroRNAs in cancer 16/348 177/7206 0.0186905705309 ko04062 Chemokine signaling pathway 3/348 201/7206 0.0187688380127 ko05034 Alcoholism 4/348 238/7206 0.0195228351121 ko04630 Jak-STAT signaling pathway 1/348 132/7206 0.0217421205399 ko04725 Cholinergic synapse 2/348 160/7206 0.0246753472019 ko04658 Th1 and Th2 cell differentiation 10/348 96/7206 0.0253648723126 ko04013 MAPK signaling pathway - fly 11/348 115/7206 0.0258634576225 ko04916 Melanogenesis 13/348 142/7206 0.0262968252227 ko04360 Axon guidance 19/348 233/7206 0.0275631743316 ko04110 Cell cycle 13/348 145/7206 0.0286966303505 ko00190 Oxidative phosphorylation 1/348 127/7206 0.0326465654149 ko03410 Base excision repair 5/348 38/7206 0.0345788726453 ko03030 DNA replication 5/348 38/7206 0.0345788726453 ko04022 cGMP-PKG signaling pathway 4/348 216/7206 0.0350331640087 ko03460 Fanconi anemia pathway 6/348 51/7206 0.0350421336157 ko05166 HTLV-I infection 22/348 292/7206 0.0354773727932 ko00590 Arachidonic acid metabolism 6/348 52/7206 0.0380687108947 ko03050 Proteasome 6/348 54/7206 0.0446094651352 ko04921 Oxytocin signaling pathway 4/348 209/7206 0.0474940760221