ko pathway ratio_in_study ratio_in_pop p_value ko05200 Pathways in cancer 43/151 492/7206 1.44030862879e-16 ko04390 Hippo signaling pathway 25/151 188/7206 7.23437602946e-14 ko05217 Basal cell carcinoma 16/151 68/7206 3.5811227519e-13 ko04360 Axon guidance 26/151 233/7206 1.44499299289e-12 ko04550 Signaling pathways regulating pluripotency of stem cells 19/151 165/7206 1.14198515456e-09 ko05224 Breast cancer 19/151 174/7206 2.82732485987e-09 ko04310 Wnt signaling pathway 18/151 181/7206 3.36298221128e-08 ko05205 Proteoglycans in cancer 21/151 271/7206 1.7845313777e-07 ko05206 MicroRNAs in cancer 16/151 177/7206 7.60090669995e-07 ko04916 Melanogenesis 14/151 142/7206 1.37334975041e-06 ko04151 PI3K-Akt signaling pathway 24/151 390/7206 1.56797749354e-06 ko04391 Hippo signaling pathway - fly 11/151 90/7206 2.38405299152e-06 ko04392 Hippo signaling pathway -multiple species 7/151 31/7206 2.66169848785e-06 ko04340 Hedgehog signaling pathway 9/151 58/7206 2.72150170411e-06 ko05166 HTLV-I infection 19/151 292/7206 9.7474125845e-06 ko05222 Small cell lung cancer 10/151 89/7206 1.49222008922e-05 ko04150 mTOR signaling pathway 14/151 184/7206 2.82949756943e-05 ko05212 Pancreatic cancer 9/151 83/7206 5.37863652797e-05 ko04350 TGF-beta signaling pathway 10/151 103/7206 5.38813446701e-05 ko04520 Adherens junction 10/151 103/7206 5.38813446701e-05 ko05220 Chronic myeloid leukemia 9/151 85/7206 6.50169793959e-05 ko04933 AGE-RAGE signaling pathway in diabetic complications 11/151 135/7206 0.000114275841235 ko04014 Ras signaling pathway 16/151 279/7206 0.000227804787145 ko04512 ECM-receptor interaction 8/151 79/7206 0.000228782075425 ko05161 Hepatitis B 12/151 173/7206 0.000258588985693 ko04015 Rap1 signaling pathway 15/151 278/7206 0.00068492565657 ko04024 cAMP signaling pathway 15/151 279/7206 0.000710898433245 ko04330 Notch signaling pathway 6/151 62/7206 0.00179193240318 ko05215 Prostate cancer 8/151 111/7206 0.00220431571159 ko04919 Thyroid hormone signaling pathway 9/151 143/7206 0.00300734715437 ko04510 Focal adhesion 12/151 240/7206 0.00441125954781 ko05152 Tuberculosis 10/151 187/7206 0.00576505658415 ko04659 Th17 cell differentiation 7/151 106/7206 0.00666778384216 ko04530 Tight junction 11/151 228/7206 0.00821621978042 ko04068 FoxO signaling pathway 9/151 167/7206 0.0082627020824 ko05210 Colorectal cancer 6/151 86/7206 0.00909972026813 ko05223 Non-small cell lung cancer 5/151 66/7206 0.0121161526052 ko04080 Neuroactive ligand-receptor interaction 2/151 423/7206 0.0126282539139 ko04066 HIF-1 signaling pathway 7/151 123/7206 0.0144975305687 ko04658 Th1 and Th2 cell differentiation 6/151 96/7206 0.015144695279 ko05145 Toxoplasmosis 7/151 126/7206 0.0163679880862 ko05146 Amoebiasis 6/151 99/7206 0.0174000352981 ko05219 Bladder cancer 4/151 48/7206 0.0176524689316 ko04370 VEGF signaling pathway 5/151 77/7206 0.0223305500846 ko04931 Insulin resistance 7/151 137/7206 0.0246922517288 ko05230 Central carbon metabolism in cancer 5/151 81/7206 0.0271113131224 ko05321 Inflammatory bowel disease (IBD) 4/151 56/7206 0.0293280148347 ko04218 Cellular senescence 8/151 177/7206 0.0321774432892 ko04110 Cell cycle 7/151 145/7206 0.0323231178321 ko04668 TNF signaling pathway 6/151 120/7206 0.0398391792067 ko05221 Acute myeloid leukemia 4/151 63/7206 0.0425644335408 ko04211 Longevity regulating pathway 6/151 123/7206 0.0440774244489 ko04341 Hedgehog signaling pathway - fly 3/151 38/7206 0.0446049875903 ko04640 Hematopoietic cell lineage 4/151 64/7206 0.0446896800519 ko01522 Endocrine resistance 6/151 124/7206 0.0455506963582