ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	76/460	423/7206	1.95961933643e-17
ko05033	Nicotine addiction	26/460	56/7206	4.77877383921e-17
ko04724	Glutamatergic synapse	39/460	152/7206	1.87002537965e-14
ko04024	cAMP signaling pathway	45/460	279/7206	4.59107517401e-09
ko04728	Dopaminergic synapse	34/460	185/7206	1.41949384934e-08
ko04713	Circadian entrainment	27/460	136/7206	8.78742585185e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	19/460	74/7206	1.09813336334e-07
ko04725	Cholinergic synapse	29/460	160/7206	2.31577970674e-07
ko04727	GABAergic synapse	23/460	110/7206	3.04065131286e-07
ko04721	Synaptic vesicle cycle	19/460	80/7206	4.14950498532e-07
ko04974	Protein digestion and absorption	21/460	96/7206	4.51784689727e-07
ko04514	Cell adhesion molecules (CAMs)	25/460	130/7206	5.03681510127e-07
ko04911	Insulin secretion	23/460	117/7206	9.67678565858e-07
ko04723	Retrograde endocannabinoid signaling	28/460	175/7206	4.96479742156e-06
ko05031	Amphetamine addiction	18/460	91/7206	1.35014507114e-05
ko04020	Calcium signaling pathway	36/460	265/7206	1.47325712167e-05
ko04261	Adrenergic signaling in cardiomyocytes	30/460	205/7206	1.54501822504e-05
ko05032	Morphine addiction	20/460	110/7206	1.69450508647e-05
ko04512	ECM-receptor interaction	16/460	79/7206	2.98729629525e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/460	79/7206	0.000115023397145
ko05030	Cocaine addiction	14/460	73/7206	0.000173130191656
ko04742	Taste transduction	12/460	61/7206	0.000390869470544
ko04260	Cardiac muscle contraction	16/460	98/7206	0.000426107883093
ko04976	Bile secretion	14/460	80/7206	0.00046796276582
ko04060	Cytokine-cytokine receptor interaction	2/460	191/7206	0.000475519504313
ko04970	Salivary secretion	15/460	95/7206	0.000916895126716
ko04010	MAPK signaling pathway	36/460	321/7206	0.000927636179326
ko03040	Spliceosome	1/460	145/7206	0.00154469521792
ko05203	Viral carcinogenesis	6/460	277/7206	0.00156246335923
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/460	59/7206	0.0037774443516
ko00190	Oxidative phosphorylation	1/460	127/7206	0.00488228437163
ko05414	Dilated cardiomyopathy	15/460	112/7206	0.00539510805659
ko05410	Hypertrophic cardiomyopathy (HCM)	14/460	100/7206	0.00555691425424
ko04142	Lysosome	2/460	151/7206	0.00612387095041
ko05322	Systemic lupus erythematosus	2/460	151/7206	0.00612387095041
ko04930	Type II diabetes mellitus	9/460	54/7206	0.00659798729869
ko04964	Proximal tubule bicarbonate reclamation	6/460	29/7206	0.00883275570988
ko04921	Oxytocin signaling pathway	23/460	209/7206	0.00920470945112
ko04360	Axon guidance	25/460	233/7206	0.00922390739383
ko04140	Autophagy - animal	3/460	164/7206	0.0094416978068
ko03013	RNA transport	3/460	166/7206	0.00945801867836
ko05164	Influenza A	3/460	167/7206	0.00951057196829
ko04068	FoxO signaling pathway	3/460	167/7206	0.00951057196829
ko00240	Pyrimidine metabolism	1/460	110/7206	0.00979996023492
ko04971	Gastric acid secretion	13/460	98/7206	0.0105609990737
ko04720	Long-term potentiation	13/460	99/7206	0.0112497507791
ko04978	Mineral absorption	7/460	40/7206	0.0122415352386
ko04120	Ubiquitin mediated proteolysis	2/460	138/7206	0.012303403135
ko05168	Herpes simplex infection	4/460	182/7206	0.0135462788641
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/460	182/7206	0.0135462788641
ko05152	Tuberculosis	4/460	187/7206	0.0140001569439
ko04022	cGMP-PKG signaling pathway	23/460	216/7206	0.0152024102381
ko04972	Pancreatic secretion	14/460	111/7206	0.0160987511647
ko04218	Cellular senescence	4/460	177/7206	0.0185741062447
ko04726	Serotonergic synapse	16/460	137/7206	0.0195070018526
ko04916	Melanogenesis	16/460	142/7206	0.0230705820104
ko05016	Huntington's disease	6/460	215/7206	0.0232392322431
ko04924	Renin secretion	11/460	86/7206	0.0235494698233
ko04110	Cell cycle	3/460	145/7206	0.0251793525848
ko04730	Long-term depression	10/460	78/7206	0.0314418196227
ko04217	Necroptosis	5/460	178/7206	0.0436220870555
ko04621	NOD-like receptor signaling pathway	4/460	157/7206	0.0462362297455
ko04630	Jak-STAT signaling pathway	3/460	132/7206	0.0475569614449
ko04973	Carbohydrate digestion and absorption	6/460	42/7206	0.0486880621578