ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 24/191 152/7206 9.95486045984e-13 ko05033 Nicotine addiction 13/191 56/7206 1.47583877021e-09 ko04721 Synaptic vesicle cycle 15/191 80/7206 1.89372512695e-09 ko04728 Dopaminergic synapse 19/191 185/7206 3.63317288429e-07 ko05030 Cocaine addiction 11/191 73/7206 2.8850645764e-06 ko05014 Amyotrophic lateral sclerosis (ALS) 10/191 74/7206 2.224323402e-05 ko04727 GABAergic synapse 12/191 110/7206 3.08676406614e-05 ko04514 Cell adhesion molecules (CAMs) 13/191 130/7206 3.66176772778e-05 ko04080 Neuroactive ligand-receptor interaction 26/191 423/7206 5.37518768734e-05 ko04713 Circadian entrainment 13/191 136/7206 5.89197629657e-05 ko04024 cAMP signaling pathway 19/191 279/7206 0.000139217075966 ko04261 Adrenergic signaling in cardiomyocytes 15/191 205/7206 0.000334561773025 ko05031 Amphetamine addiction 9/191 91/7206 0.000642729509039 ko04010 MAPK signaling pathway 19/191 321/7206 0.000963860579733 ko04911 Insulin secretion 10/191 117/7206 0.00103053607539 ko04723 Retrograde endocannabinoid signaling 12/191 175/7206 0.00229201002189 ko05032 Morphine addiction 8/191 110/7206 0.00860333026273 ko04725 Cholinergic synapse 10/191 160/7206 0.00987582337607 ko05010 Alzheimer's disease 12/191 202/7206 0.011337601394 ko04930 Type II diabetes mellitus 5/191 54/7206 0.0137295754641 ko04260 Cardiac muscle contraction 7/191 98/7206 0.0149748874618 ko04720 Long-term potentiation 7/191 99/7206 0.0157645383075 ko04020 Calcium signaling pathway 14/191 265/7206 0.0165627633748 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 6/191 79/7206 0.0179829148484 ko04072 Phospholipase D signaling pathway 11/191 197/7206 0.0200608636228 ko04921 Oxytocin signaling pathway 11/191 209/7206 0.0261883385615 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/191 1/7206 0.0265056897032 ko04726 Serotonergic synapse 8/191 137/7206 0.0288222013236 ko04970 Salivary secretion 6/191 95/7206 0.039887719668 ko05410 Hypertrophic cardiomyopathy (HCM) 6/191 100/7206 0.0491765997632