ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	189/971	423/7206	6.02566649998e-60
ko05033	Nicotine addiction	49/971	56/7206	6.8823735514e-36
ko04724	Glutamatergic synapse	84/971	152/7206	6.20761142952e-35
ko04727	GABAergic synapse	62/971	110/7206	1.24148587093e-26
ko05032	Morphine addiction	62/971	110/7206	1.24148587093e-26
ko04713	Circadian entrainment	68/971	136/7206	5.36171914112e-25
ko04728	Dopaminergic synapse	78/971	185/7206	1.59040590104e-22
ko04723	Retrograde endocannabinoid signaling	73/971	175/7206	8.26552342857e-21
ko04725	Cholinergic synapse	68/971	160/7206	5.48359565378e-20
ko04024	cAMP signaling pathway	95/971	279/7206	2.58743504823e-19
ko04721	Synaptic vesicle cycle	44/971	80/7206	1.17045443741e-18
ko04020	Calcium signaling pathway	88/971	265/7206	4.66957107257e-17
ko04921	Oxytocin signaling pathway	72/971	209/7206	3.67812600166e-15
ko04726	Serotonergic synapse	55/971	137/7206	4.47099879496e-15
ko04742	Taste transduction	34/971	61/7206	6.1742853824e-15
ko04911	Insulin secretion	49/971	117/7206	2.0292724593e-14
ko04744	Phototransduction	24/971	36/7206	2.47398998074e-13
ko05031	Amphetamine addiction	39/971	91/7206	4.07890803846e-12
ko04720	Long-term potentiation	41/971	99/7206	4.42017593604e-12
ko04261	Adrenergic signaling in cardiomyocytes	64/971	205/7206	2.29203739701e-11
ko04970	Salivary secretion	36/971	95/7206	1.73547020871e-09
ko03040	Spliceosome	1/971	145/7206	2.29970218416e-08
ko05030	Cocaine addiction	28/971	73/7206	8.32714724167e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	28/971	74/7206	1.17030863064e-07
ko05168	Herpes simplex infection	4/971	182/7206	1.31861347699e-07
ko04060	Cytokine-cytokine receptor interaction	5/971	191/7206	2.68666463761e-07
ko05203	Viral carcinogenesis	12/971	277/7206	5.46914438098e-07
ko04925	Aldosterone synthesis and secretion	34/971	105/7206	6.54287199074e-07
ko04971	Gastric acid secretion	32/971	98/7206	7.62407877217e-07
ko05164	Influenza A	4/971	167/7206	9.02203431092e-07
ko04010	MAPK signaling pathway	75/971	321/7206	9.14281903141e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/971	79/7206	2.05715588353e-06
ko04260	Cardiac muscle contraction	30/971	98/7206	8.06917921921e-06
ko04740	Olfactory transduction	26/971	80/7206	9.07666129584e-06
ko05322	Systemic lupus erythematosus	4/971	151/7206	9.22606727002e-06
ko04022	cGMP-PKG signaling pathway	52/971	216/7206	1.74518720403e-05
ko04730	Long-term depression	25/971	78/7206	2.93715773446e-05
ko04972	Pancreatic secretion	31/971	111/7206	5.60382866983e-05
ko04745	Phototransduction - fly	15/971	38/7206	5.8833731049e-05
ko05414	Dilated cardiomyopathy	31/971	112/7206	6.24811884282e-05
ko04070	Phosphatidylinositol signaling system	31/971	112/7206	6.24811884282e-05
ko04141	Protein processing in endoplasmic reticulum	8/971	184/7206	6.50128965492e-05
ko05169	Epstein-Barr virus infection	10/971	206/7206	6.85325088802e-05
ko04072	Phospholipase D signaling pathway	47/971	197/7206	7.22149474445e-05
ko04360	Axon guidance	53/971	233/7206	8.27413714906e-05
ko03013	RNA transport	7/971	166/7206	0.000118465296662
ko04924	Renin secretion	25/971	86/7206	0.000161727248585
ko04540	Gap junction	33/971	128/7206	0.00019201699317
ko04120	Ubiquitin mediated proteolysis	5/971	138/7206	0.00020309723613
ko04966	Collecting duct acid secretion	11/971	26/7206	0.000280169287933
ko04612	Antigen processing and presentation	1/971	77/7206	0.000307393924499
ko04514	Cell adhesion molecules (CAMs)	32/971	130/7206	0.000613598500644
ko04110	Cell cycle	7/971	145/7206	0.000842049199049
ko04621	NOD-like receptor signaling pathway	8/971	157/7206	0.000846238671969
ko05205	Proteoglycans in cancer	19/971	271/7206	0.00101370022402
ko05162	Measles	5/971	120/7206	0.00108102096844
ko04610	Complement and coagulation cascades	2/971	79/7206	0.00144778876838
ko03008	Ribosome biogenesis in eukaryotes	2/971	79/7206	0.00144778876838
ko05161	Hepatitis B	10/971	173/7206	0.00148002191545
ko05410	Hypertrophic cardiomyopathy (HCM)	25/971	100/7206	0.00168397753278
ko04750	Inflammatory mediator regulation of TRP channels	29/971	122/7206	0.00184316099025
ko04146	Peroxisome	3/971	89/7206	0.00256525653628
ko04915	Estrogen signaling pathway	30/971	131/7206	0.00275421824538
ko05166	HTLV-I infection	23/971	292/7206	0.00288587707263
ko00240	Pyrimidine metabolism	5/971	110/7206	0.00295261600667
ko04014	Ras signaling pathway	55/971	279/7206	0.00303226171818
ko00310	Lysine degradation	2/971	73/7206	0.00307471676181
ko05110	Vibrio cholerae infection	17/971	63/7206	0.00435848176155
ko00480	Glutathione metabolism	1/971	55/7206	0.00507314495906
ko04626	Plant-pathogen interaction	7/971	18/7206	0.00649684486327
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/971	14/7206	0.00674819956671
ko00590	Arachidonic acid metabolism	1/971	52/7206	0.00753246311074
ko04140	Autophagy - animal	11/971	164/7206	0.00758701860817
ko04350	TGF-beta signaling pathway	5/971	103/7206	0.00807069430323
ko04630	Jak-STAT signaling pathway	8/971	132/7206	0.00954474642613
ko05140	Leishmaniasis	3/971	75/7206	0.0103782246877
ko04142	Lysosome	10/971	151/7206	0.0108990056379
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/971	182/7206	0.0109017927279
ko04964	Proximal tubule bicarbonate reclamation	9/971	29/7206	0.0113599444521
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/971	59/7206	0.0117758028328
ko04976	Bile secretion	19/971	80/7206	0.0122349251216
ko04330	Notch signaling pathway	2/971	62/7206	0.0136952031238
ko04214	Apoptosis - fly	3/971	72/7206	0.0146517615045
ko05231	Choline metabolism in cancer	28/971	134/7206	0.0149216724884
ko04064	NF-kappa B signaling pathway	5/971	96/7206	0.0149925358044
ko03018	RNA degradation	4/971	84/7206	0.0150332321569
ko04550	Signaling pathways regulating pluripotency of stem cells	12/971	165/7206	0.0152240719991
ko04912	GnRH signaling pathway	26/971	122/7206	0.0153841206493
ko05034	Alcoholism	45/971	238/7206	0.0156273793942
ko03420	Nucleotide excision repair	1/971	46/7206	0.0165246136253
ko04670	Leukocyte transendothelial migration	11/971	151/7206	0.021766582782
ko05215	Prostate cancer	7/971	111/7206	0.0241488039106
ko05144	Malaria	1/971	45/7206	0.0253202126872
ko00071	Fatty acid degradation	1/971	45/7206	0.0253202126872
ko04510	Focal adhesion	21/971	240/7206	0.0269564576857
ko05222	Small cell lung cancer	5/971	89/7206	0.027581658916
ko05010	Alzheimer's disease	38/971	202/7206	0.0280689136329
ko05321	Inflammatory bowel disease (IBD)	2/971	56/7206	0.0283512798247
ko04015	Rap1 signaling pathway	50/971	278/7206	0.031063755948
ko04371	Apelin signaling pathway	34/971	177/7206	0.0332690876684
ko04658	Th1 and Th2 cell differentiation	6/971	96/7206	0.0346067584241
ko05145	Toxoplasmosis	9/971	126/7206	0.0346274372948
ko00140	Steroid hormone biosynthesis	1/971	41/7206	0.0363258756106
ko04657	IL-17 signaling pathway	5/971	87/7206	0.0380447508508
ko04115	p53 signaling pathway	4/971	74/7206	0.0392169631535
ko05200	Pathways in cancer	51/971	492/7206	0.0398602457288
ko01524	Platinum drug resistance	4/971	76/7206	0.0403564969957
ko04622	RIG-I-like receptor signaling pathway	3/971	62/7206	0.0404123424932
ko05418	Fluid shear stress and atherosclerosis	14/971	173/7206	0.0414663595482
ko04930	Type II diabetes mellitus	13/971	54/7206	0.0418772508623
ko05016	Huntington's disease	19/971	215/7206	0.0424239218178
ko04217	Necroptosis	15/971	178/7206	0.0452461982235
ko04210	Apoptosis	15/971	180/7206	0.0456746614572
ko04062	Chemokine signaling pathway	37/971	201/7206	0.0458019240743