ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	174/948	423/7206	3.5077271781e-50
ko05033	Nicotine addiction	45/948	56/7206	3.18297345264e-30
ko04724	Glutamatergic synapse	75/948	152/7206	1.07462076822e-27
ko04721	Synaptic vesicle cycle	46/948	80/7206	5.73409336932e-21
ko04728	Dopaminergic synapse	74/948	185/7206	2.0126979474e-20
ko05032	Morphine addiction	54/948	110/7206	4.40118505554e-20
ko04713	Circadian entrainment	61/948	136/7206	5.29224988691e-20
ko04727	GABAergic synapse	51/948	110/7206	1.13595851229e-17
ko04024	cAMP signaling pathway	90/948	279/7206	2.96558134686e-17
ko04725	Cholinergic synapse	63/948	160/7206	3.92113161201e-17
ko04723	Retrograde endocannabinoid signaling	64/948	175/7206	1.58524139206e-15
ko04020	Calcium signaling pathway	83/948	265/7206	4.61362800259e-15
ko04921	Oxytocin signaling pathway	67/948	209/7206	6.36526658179e-13
ko04911	Insulin secretion	46/948	117/7206	8.34496770587e-13
ko04726	Serotonergic synapse	50/948	137/7206	2.3704777393e-12
ko04742	Taste transduction	30/948	61/7206	9.69571114559e-12
ko04261	Adrenergic signaling in cardiomyocytes	63/948	205/7206	2.74785336348e-11
ko04720	Long-term potentiation	39/948	99/7206	4.39529501163e-11
ko05031	Amphetamine addiction	37/948	91/7206	4.65205263749e-11
ko04970	Salivary secretion	36/948	95/7206	8.88484145096e-10
ko03040	Spliceosome	1/948	145/7206	3.67457677411e-08
ko04022	cGMP-PKG signaling pathway	56/948	216/7206	3.19130826667e-07
ko04360	Axon guidance	59/948	233/7206	3.27749985946e-07
ko04060	Cytokine-cytokine receptor interaction	5/948	191/7206	6.06265028335e-07
ko05030	Cocaine addiction	26/948	73/7206	8.13409517358e-07
ko04730	Long-term depression	27/948	78/7206	9.60862674049e-07
ko05203	Viral carcinogenesis	12/948	277/7206	1.09783133425e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	26/948	74/7206	1.09978314502e-06
ko05164	Influenza A	4/948	167/7206	2.10348369603e-06
ko05322	Systemic lupus erythematosus	3/948	151/7206	2.12476519607e-06
ko04971	Gastric acid secretion	31/948	98/7206	2.34752798339e-06
ko04744	Phototransduction	16/948	36/7206	3.94479413468e-06
ko05168	Herpes simplex infection	6/948	182/7206	6.64554169027e-06
ko04925	Aldosterone synthesis and secretion	31/948	105/7206	7.63194959436e-06
ko04745	Phototransduction - fly	16/948	38/7206	9.27716731301e-06
ko04924	Renin secretion	27/948	86/7206	1.30365348552e-05
ko04010	MAPK signaling pathway	70/948	321/7206	1.35206889962e-05
ko04621	NOD-like receptor signaling pathway	5/948	157/7206	3.51860207443e-05
ko05169	Epstein-Barr virus infection	9/948	206/7206	3.57596963712e-05
ko04966	Collecting duct acid secretion	12/948	26/7206	4.11094402412e-05
ko04120	Ubiquitin mediated proteolysis	4/948	138/7206	5.84788698363e-05
ko04514	Cell adhesion molecules (CAMs)	34/948	130/7206	6.00497966201e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/948	79/7206	6.00522370594e-05
ko04740	Olfactory transduction	24/948	80/7206	7.00516581518e-05
ko04260	Cardiac muscle contraction	27/948	98/7206	0.000120498881132
ko03013	RNA transport	7/948	166/7206	0.000167405000515
ko04972	Pancreatic secretion	29/948	111/7206	0.000189767986609
ko04610	Complement and coagulation cascades	1/948	79/7206	0.000315300181148
ko04141	Protein processing in endoplasmic reticulum	9/948	184/7206	0.000345646612199
ko04612	Antigen processing and presentation	1/948	77/7206	0.000488290980662
ko04540	Gap junction	31/948	128/7206	0.000528916194078
ko05110	Vibrio cholerae infection	18/948	63/7206	0.00104697698953
ko04064	NF-kappa B signaling pathway	3/948	96/7206	0.00125263206388
ko00240	Pyrimidine metabolism	4/948	110/7206	0.00147748296139
ko04070	Phosphatidylinositol signaling system	27/948	112/7206	0.00162101659879
ko04110	Cell cycle	7/948	145/7206	0.00167991054322
ko03008	Ribosome biogenesis in eukaryotes	2/948	79/7206	0.00216644896014
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/948	182/7206	0.00254168685728
ko04072	Phospholipase D signaling pathway	41/948	197/7206	0.00255349598179
ko04014	Ras signaling pathway	54/948	279/7206	0.00278059773126
ko04964	Proximal tubule bicarbonate reclamation	10/948	29/7206	0.00278811572492
ko04350	TGF-beta signaling pathway	4/948	103/7206	0.00289491367963
ko05414	Dilated cardiomyopathy	26/948	112/7206	0.00289680108308
ko05140	Leishmaniasis	2/948	75/7206	0.00312390537326
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/948	59/7206	0.00335144175482
ko00330	Arginine and proline metabolism	1/948	61/7206	0.00352130550154
ko04146	Peroxisome	3/948	89/7206	0.00383780004292
ko04915	Estrogen signaling pathway	29/948	131/7206	0.00384918811719
ko04214	Apoptosis - fly	2/948	72/7206	0.00453730332804
ko04626	Plant-pathogen interaction	7/948	18/7206	0.00567961802036
ko05162	Measles	6/948	120/7206	0.00586733360661
ko05161	Hepatitis B	11/948	173/7206	0.00591442859979
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/948	14/7206	0.00598485155602
ko04750	Inflammatory mediator regulation of TRP channels	27/948	122/7206	0.00626074184283
ko00480	Glutathione metabolism	1/948	55/7206	0.00780637768271
ko05205	Proteoglycans in cancer	22/948	271/7206	0.0102133287345
ko04976	Bile secretion	19/948	80/7206	0.0111859741629
ko04722	Neurotrophin signaling pathway	32/948	160/7206	0.0127821503395
ko04330	Notch signaling pathway	2/948	62/7206	0.0136738938739
ko04668	TNF signaling pathway	7/948	120/7206	0.0136750349138
ko01524	Platinum drug resistance	3/948	76/7206	0.0153216484381
ko05166	HTLV-I infection	25/948	292/7206	0.0167314407796
ko01200	Carbon metabolism	8/948	128/7206	0.0169892991949
ko04071	Sphingolipid signaling pathway	32/948	162/7206	0.01793766767
ko03018	RNA degradation	4/948	84/7206	0.0214241263304
ko05145	Toxoplasmosis	8/948	126/7206	0.0227370062873
ko04371	Apelin signaling pathway	34/948	177/7206	0.0234980160006
ko03022	Basal transcription factors	1/948	44/7206	0.0246591274164
ko04930	Type II diabetes mellitus	13/948	54/7206	0.0247640830738
ko00071	Fatty acid degradation	1/948	45/7206	0.024833850276
ko00620	Pyruvate metabolism	1/948	46/7206	0.0254960761548
ko03420	Nucleotide excision repair	1/948	46/7206	0.0254960761548
ko04923	Regulation of lipolysis in adipocytes	17/948	77/7206	0.0266269765438
ko04630	Jak-STAT signaling pathway	9/948	132/7206	0.026820765685
ko05321	Inflammatory bowel disease (IBD)	2/948	56/7206	0.0281245248312
ko05146	Amoebiasis	6/948	99/7206	0.0350260598345
ko00140	Steroid hormone biosynthesis	1/948	41/7206	0.0363079432624
ko04657	IL-17 signaling pathway	5/948	87/7206	0.0374470315817
ko05222	Small cell lung cancer	5/948	89/7206	0.0382865060871
ko04640	Hematopoietic cell lineage	3/948	64/7206	0.040690627556
ko00280	Valine, leucine and isoleucine degradation	2/948	54/7206	0.0406912992302
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/948	92/7206	0.0420489357679
ko05214	Glioma	17/948	79/7206	0.0420798824232
ko04015	Rap1 signaling pathway	48/948	278/7206	0.0459631543632