ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	111/589	423/7206	4.41670981281e-31
ko04724	Glutamatergic synapse	53/589	152/7206	4.05761397215e-21
ko05033	Nicotine addiction	28/589	56/7206	1.64630842426e-16
ko04713	Circadian entrainment	42/589	136/7206	8.41940315641e-15
ko04727	GABAergic synapse	35/589	110/7206	5.82894034896e-13
ko04728	Dopaminergic synapse	46/589	185/7206	2.84996206373e-12
ko05032	Morphine addiction	33/589	110/7206	1.67564307275e-11
ko04972	Pancreatic secretion	33/589	111/7206	2.2044878232e-11
ko04024	cAMP signaling pathway	56/589	279/7206	1.50345918275e-10
ko04725	Cholinergic synapse	39/589	160/7206	2.63105426117e-10
ko04723	Retrograde endocannabinoid signaling	41/589	175/7206	3.35548111541e-10
ko04911	Insulin secretion	32/589	117/7206	4.87773983395e-10
ko04970	Salivary secretion	27/589	95/7206	4.5424364957e-09
ko04721	Synaptic vesicle cycle	24/589	80/7206	1.02241771649e-08
ko04976	Bile secretion	23/589	80/7206	5.06276639669e-08
ko04726	Serotonergic synapse	31/589	137/7206	1.19278605835e-07
ko05031	Amphetamine addiction	24/589	91/7206	1.58968823848e-07
ko04921	Oxytocin signaling pathway	38/589	209/7206	2.09720731059e-06
ko05030	Cocaine addiction	19/589	73/7206	3.88092101622e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	19/589	74/7206	4.83077257616e-06
ko04925	Aldosterone synthesis and secretion	23/589	105/7206	9.2226721865e-06
ko04978	Mineral absorption	13/589	40/7206	9.69415344146e-06
ko04744	Phototransduction	12/589	36/7206	1.59772181887e-05
ko04742	Taste transduction	16/589	61/7206	2.02607025117e-05
ko04060	Cytokine-cytokine receptor interaction	2/589	191/7206	2.17695889887e-05
ko05203	Viral carcinogenesis	6/589	277/7206	2.79416193802e-05
ko04971	Gastric acid secretion	21/589	98/7206	3.19682965142e-05
ko04730	Long-term depression	18/589	78/7206	4.13104155436e-05
ko04514	Cell adhesion molecules (CAMs)	25/589	130/7206	5.48665079789e-05
ko04964	Proximal tubule bicarbonate reclamation	10/589	29/7206	5.91332574979e-05
ko05322	Systemic lupus erythematosus	1/589	151/7206	6.16707392256e-05
ko04261	Adrenergic signaling in cardiomyocytes	34/589	205/7206	7.29533780426e-05
ko03040	Spliceosome	1/589	145/7206	9.02600915491e-05
ko04720	Long-term potentiation	20/589	99/7206	0.000117714904205
ko04020	Calcium signaling pathway	40/589	265/7206	0.00013099889684
ko05164	Influenza A	2/589	167/7206	0.000145784757992
ko05168	Herpes simplex infection	3/589	182/7206	0.000282370033984
ko04924	Renin secretion	17/589	86/7206	0.000491720975924
ko05162	Measles	1/589	120/7206	0.00063351961253
ko04540	Gap junction	22/589	128/7206	0.00082521409307
ko04022	cGMP-PKG signaling pathway	32/589	216/7206	0.000894085218146
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/589	182/7206	0.0013593870636
ko05205	Proteoglycans in cancer	9/589	271/7206	0.00144896346679
ko05016	Huntington's disease	6/589	215/7206	0.00147357408641
ko04350	TGF-beta signaling pathway	1/589	103/7206	0.00302972371815
ko04740	Olfactory transduction	14/589	80/7206	0.00595978728257
ko04010	MAPK signaling pathway	40/589	321/7206	0.00646398871681
ko04120	Ubiquitin mediated proteolysis	3/589	138/7206	0.00669424648613
ko04974	Protein digestion and absorption	16/589	96/7206	0.00705699463719
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/589	59/7206	0.00745508615525
ko04510	Focal adhesion	9/589	240/7206	0.00802885996194
ko05166	HTLV-I infection	12/589	292/7206	0.00839930860129
ko05169	Epstein-Barr virus infection	7/589	206/7206	0.00916740216636
ko04150	mTOR signaling pathway	6/589	184/7206	0.00931804344581
ko03013	RNA transport	5/589	166/7206	0.00948739806788
ko04550	Signaling pathways regulating pluripotency of stem cells	5/589	165/7206	0.0133815182734
ko05161	Hepatitis B	6/589	173/7206	0.0167903509843
ko05206	MicroRNAs in cancer	6/589	177/7206	0.0171002055844
ko04218	Cellular senescence	6/589	177/7206	0.0171002055844
ko04610	Complement and coagulation cascades	1/589	79/7206	0.0203386306413
ko03008	Ribosome biogenesis in eukaryotes	1/589	79/7206	0.0203386306413
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/589	14/7206	0.0228130636742
ko04142	Lysosome	5/589	151/7206	0.0235449986381
ko04915	Estrogen signaling pathway	18/589	131/7206	0.0241715249797
ko04630	Jak-STAT signaling pathway	4/589	132/7206	0.0241952522585
ko04918	Thyroid hormone synthesis	13/589	86/7206	0.027108042259
ko04110	Cell cycle	5/589	145/7206	0.0315645295674
ko04745	Phototransduction - fly	7/589	38/7206	0.032015547572
ko00190	Oxidative phosphorylation	4/589	127/7206	0.0329115840227
ko05215	Prostate cancer	3/589	111/7206	0.0339413379211
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/589	79/7206	0.0350944107571
ko04217	Necroptosis	7/589	178/7206	0.0365375225659
ko04621	NOD-like receptor signaling pathway	6/589	157/7206	0.039375952161
ko05200	Pathways in cancer	28/589	492/7206	0.0402323675254
ko03018	RNA degradation	2/589	84/7206	0.0454004340768
ko05220	Chronic myeloid leukemia	2/589	85/7206	0.0454006684776