ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	23/374	56/7206	9.49078997191e-16
ko04724	Glutamatergic synapse	36/374	152/7206	4.63706631698e-15
ko04080	Neuroactive ligand-receptor interaction	61/374	423/7206	8.39610115128e-14
ko04727	GABAergic synapse	26/374	110/7206	3.587318216e-11
ko04728	Dopaminergic synapse	34/374	185/7206	5.94345678727e-11
ko04723	Retrograde endocannabinoid signaling	31/374	175/7206	1.12758595956e-09
ko05032	Morphine addiction	24/374	110/7206	1.21428919011e-09
ko04721	Synaptic vesicle cycle	20/374	80/7206	2.43415051958e-09
ko04010	MAPK signaling pathway	43/374	321/7206	5.90898051226e-09
ko04514	Cell adhesion molecules (CAMs)	24/374	130/7206	3.99397541386e-08
ko04713	Circadian entrainment	24/374	136/7206	9.83056185584e-08
ko04360	Axon guidance	32/374	233/7206	3.33665784499e-07
ko04024	cAMP signaling pathway	35/374	279/7206	1.10518561895e-06
ko04911	Insulin secretion	20/374	117/7206	1.97455394484e-06
ko04261	Adrenergic signaling in cardiomyocytes	27/374	205/7206	6.41927127518e-06
ko05030	Cocaine addiction	14/374	73/7206	1.80791113102e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	14/374	74/7206	2.12640088433e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/374	14/7206	3.95229169361e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/374	79/7206	4.57693695138e-05
ko04725	Cholinergic synapse	21/374	160/7206	7.31792218861e-05
ko04260	Cardiac muscle contraction	15/374	98/7206	0.00014169911142
ko04921	Oxytocin signaling pathway	23/374	209/7206	0.000644980015772
ko04726	Serotonergic synapse	17/374	137/7206	0.000684226627811
ko04060	Cytokine-cytokine receptor interaction	1/374	191/7206	0.000729142139974
ko05031	Amphetamine addiction	13/374	91/7206	0.000771134963629
ko05414	Dilated cardiomyopathy	14/374	112/7206	0.00185964126057
ko05410	Hypertrophic cardiomyopathy (HCM)	13/374	100/7206	0.00187476904032
ko05203	Viral carcinogenesis	4/374	277/7206	0.00204644651345
ko04964	Proximal tubule bicarbonate reclamation	6/374	29/7206	0.00322263436726
ko04150	mTOR signaling pathway	2/374	184/7206	0.00621580431757
ko04217	Necroptosis	2/374	178/7206	0.00899003880189
ko05164	Influenza A	2/374	167/7206	0.0123946550526
ko04068	FoxO signaling pathway	2/374	167/7206	0.0123946550526
ko00190	Oxidative phosphorylation	1/374	127/7206	0.0146646938185
ko01200	Carbon metabolism	1/374	128/7206	0.0146851328265
ko04972	Pancreatic secretion	12/374	111/7206	0.0147038453802
ko00512	Mucin type O-glycan biosynthesis	5/374	29/7206	0.0155338943016
ko04970	Salivary secretion	11/374	95/7206	0.0159313684152
ko04621	NOD-like receptor signaling pathway	2/374	157/7206	0.0174173672995
ko04720	Long-term potentiation	11/374	99/7206	0.0181133365086
ko04140	Autophagy - animal	2/374	164/7206	0.0183690149642
ko05162	Measles	1/374	120/7206	0.0212181998421
ko04940	Type I diabetes mellitus	5/374	32/7206	0.0232101467072
ko05205	Proteoglycans in cancer	6/374	271/7206	0.0241273036854
ko05322	Systemic lupus erythematosus	2/374	151/7206	0.0246163127737
ko00430	Taurine and hypotaurine metabolism	3/374	14/7206	0.0329349395995
ko04072	Phospholipase D signaling pathway	17/374	197/7206	0.0337486103166
ko05169	Epstein-Barr virus infection	4/374	206/7206	0.035967369424
ko04218	Cellular senescence	3/374	177/7206	0.0367546471626
ko04742	Taste transduction	7/374	61/7206	0.0375037806277
ko02024	Quorum sensing	3/374	15/7206	0.0396254585375
ko04022	cGMP-PKG signaling pathway	18/374	216/7206	0.0419190488491
ko00250	Alanine, aspartate and glutamate metabolism	5/374	38/7206	0.0449983702635
ko04915	Estrogen signaling pathway	12/374	131/7206	0.0461385629463
ko00240	Pyrimidine metabolism	1/374	110/7206	0.0462992603225
ko00230	Purine metabolism	4/374	194/7206	0.0472059165112
ko04020	Calcium signaling pathway	21/374	265/7206	0.0475295672876
ko04611	Platelet activation	3/374	163/7206	0.0485102845831
ko04550	Signaling pathways regulating pluripotency of stem cells	3/374	165/7206	0.0488000177297
ko03013	RNA transport	3/374	166/7206	0.0490587718679
ko04120	Ubiquitin mediated proteolysis	2/374	138/7206	0.049220198892